KEGG   Homo sapiens (human): 3984Help
Entry
3984              CDS       T01001                                 

Gene name
LIMK1, LIMK, LIMK-1
Definition
(RefSeq) LIM domain kinase 1
  KO
K05743  
LIM domain kinase 1 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
Axon guidance
Fc gamma R-mediated phagocytosis
Regulation of actin cytoskeleton
Disease
H01439  
Williams-Beuren syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    3984 (LIMK1)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    3984 (LIMK1)
  Development
   04360 Axon guidance
    3984 (LIMK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     3984 (LIMK1)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: TKL group
  LISK family [OT]
   3984 (LIMK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P53667(Tchem)
UniProt: 
Structure
PDB: 

Jmol
Position
7q11.23
AA seq 647 aa AA seqDB search
MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLS
HQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGD
GDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSV
SIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEID
LLIQETSRLLQLTLEHDPHDTLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSID
RSPGAGSLGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRE
TGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGT
LRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFG
LARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLC
EIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL
EHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD
NT seq 1944 nt NT seq  +upstreamnt  +downstreamnt
atgaggttgacgctactttgttgcacctggagggaagaacgtatgggagaggaaggaagc
gagttgcccgtgtgtgcaagctgcggccagaggatctatgatggccagtacctccaggcc
ctgaacgcggactggcacgcagactgcttcaggtgttgtgactgcagtgcctccctgtcg
caccagtactatgagaaggatgggcagctcttctgcaagaaggactactgggcccgctat
ggcgagtcctgccatgggtgctctgagcaaatcaccaagggactggttatggtggctggg
gagctgaagtaccaccccgagtgtttcatctgcctcacgtgtgggacctttatcggtgac
ggggacacctacacgctggtggagcactccaagctgtactgcgggcactgctactaccag
actgtggtgacccccgtcatcgagcagatcctgcctgactcccctggctcccacctgccc
cacaccgtcaccctggtgtccatcccagcctcatctcatggcaagcgtggactttcagtc
tccattgaccccccgcacggcccaccgggctgtggcaccgagcactcacacaccgtccgc
gtccagggagtggatccgggctgcatgagcccagatgtgaagaattccatccacgtcgga
gaccggatcttggaaatcaatggcacgcccatccgaaatgtgcccctggacgagattgac
ctgctgattcaggaaaccagccgcctgctccagctgaccctcgagcatgaccctcacgat
acactgggccacgggctggggcctgagaccagccccctgagctctccggcttatactccc
agcggggaggcgggcagctctgcccggcagaaacctgtcttgaggagctgcagcatcgac
aggtctccgggcgctggctcactgggctccccggcctcccagcgcaaggacctgggtcgc
tctgagtccctccgcgtagtctgccggccacaccgcatcttccggccgtcggacctcatc
cacggggaggtgctgggcaagggctgcttcggccaggctatcaaggtgacacaccgtgag
acaggtgaggtgatggtgatgaaggagctgatccggttcgacgaggagacccagaggacg
ttcctcaaggaggtgaaggtcatgcgatgcctggaacaccccaacgtgctcaagttcatc
ggggtgctctacaaggacaagaggctcaacttcatcactgagtacatcaagggcggcacg
ctccggggcatcatcaagagcatggacagccagtacccatggagccagagagtgagcttt
gccaaggacatcgcatcagggatggcctacctccactccatgaacatcatccaccgagac
ctcaactcccacaactgcctggtccgcgagaacaagaatgtggtggtggctgacttcggg
ctggcgcgtctcatggtggacgagaagactcagcctgagggcctgcggagcctcaagaag
ccagaccgcaagaagcgctacaccgtggtgggcaacccctactggatggcacctgagatg
atcaacggccgcagctatgatgagaaggtggatgtgttctcctttgggatcgtcctgtgc
gagatcatcgggcgggtgaacgcagaccctgactacctgccccgcaccatggactttggc
ctcaacgtgcgaggattcctggaccgctactgccccccaaactgccccccgagcttcttc
cccatcaccgtgcgctgttgcgatctggaccccgagaagaggccatcctttgtgaagctg
gaacactggctggagaccctccgcatgcacctggccggccacctgccactgggcccacag
ctggagcagctggacagaggtttctgggagacctaccggcgcggcgagagcggactgcct
gcccaccctgaggtccccgactga

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