KEGG   Homo sapiens (human): 3985Help
Entry
3985              CDS       T01001                                 

Gene name
LIMK2
Definition
LIM domain kinase 2 (EC:2.7.11.1)
Orthology
K05744  
LIM domain kinase 2 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
Axon guidance
Fc gamma R-mediated phagocytosis
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    3985 (LIMK2)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    3985 (LIMK2)
  Development
   04360 Axon guidance
    3985 (LIMK2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     3985 (LIMK2)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: TKL group
  LISK family [OT]
   3985 (LIMK2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
22q12.2
AA seq 686 aa AA seqDB search
MGSYLSVPAYFTSRDLFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTG
PFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTES
VQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPG
DRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAG
HPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSY
SQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMR
SLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAY
LHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK
KRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVK
LFWEKFVPTDCPPAFFPLAAICCRLEPESRAPPGAAGEGPGCADDEGPVRRQGKVTIKYD
PKELRKHLNLEEWILEQLTRLYDCQEEEISELEIDVDELLDMESDDAWASRVKELLVDCY
KPTEAFISGLLDKIRAMQKLSTPQKK
NT seq 2061 nt NT seq  +upstreamnt  +downstreamnt
atggggagttacttgtcagtcccggcttacttcacctccagagacctgtttcggtgttca
gaatgccaggattccctcaccaactggtactatgagaaggatgggaagctctactgcccc
aaggactactgggggaagtttggggagttctgtcatgggtgctccctgctgatgacaggg
ccttttatggtggctggggagttcaagtaccacccagagtgctttgcctgtatgagctgc
aaggtgatcattgaggatggggatgcatatgcactggtgcagcatgccaccctctactgt
gggaagtgccacaatgaggtggtgctggcacccatgtttgagagactctccacagagtct
gttcaggagcagctgccctactctgtcacgctcatctccatgccggccaccactgaaggc
aggcggggcttctccgtgtccgtggagagtgcctgctccaactacgccaccactgtgcaa
gtgaaagaggtcaaccggatgcacatcagtcccaacaatcgaaacgccatccaccctggg
gaccgcatcctggagatcaatgggacccccgtccgcacacttcgagtggaggaggtggag
gatgcaattagccagacgagccagacacttcagctgttgattgaacatgaccccgtctcc
caacgcctggaccagctgcggctggaggcccggctcgctcctcacatgcagaatgccgga
cacccccacgccctcagcaccctggacaccaaggagaatctggaggggacactgaggaga
cgttccctaaggcgcagtaacagtatctccaagtcccctggccccagctccccaaaggag
cccctgctgttcagccgtgacatcagccgctcagaatcccttcgttgttccagcagctat
tcacagcagatcttccggccctgtgacctaatccatggggaggtcctggggaagggcttc
tttgggcaggctatcaaggtgacacacaaagccacgggcaaagtgatggtcatgaaagag
ttaattcgatgtgatgaggagacccagaaaacttttctgactgaggtgaaagtgatgcgc
agcctggaccaccccaatgtgctcaagttcattggtgtgctgtacaaggataagaagctg
aacctcctgacagagtacattgaggggggcacactgaaggactttctgcgcagtatggat
ccgttcccctggcagcagaaggtcaggtttgccaaaggaatcgcctccggaatggcctat
ttgcactctatgtgcatcatccaccgggatctgaactcgcacaactgcctcatcaagttg
gacaagactgtggtggtggcagactttgggctgtcacggctcatagtggaagagaggaaa
agggcccccatggagaaggccaccaccaagaaacgcaccttgcgcaagaacgaccgcaag
aagcgctacacggtggtgggaaacccctactggatggcccctgagatgctgaacggaaag
agctatgatgagacggtggatatcttctcctttgggatcgttctctgtgagatcattggg
caggtgtatgcagatcctgactgccttccccgaacactggactttggcctcaacgtgaag
cttttctgggagaagtttgttcccacagattgtcccccggccttcttcccgctggccgcc
atctgctgcagactggagcctgagagcagagccccccccggggccgcaggagagggcccg
ggctgcgcggatgatgagggcccagtgaggcgccaagggaaggtcaccatcaagtatgac
cccaaggagctacggaagcacctcaacctagaggagtggatcctggagcagctcacgcgc
ctctacgactgccaggaagaggagatctcagaactagagattgacgtggatgagctcctg
gacatggagagtgacgatgcctgggcttccagggtcaaggagctgctggttgactgttac
aaacccacagaggccttcatctctggcctgctggacaagatccgggccatgcagaagctg
agcacaccccagaagaagtga

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