| Entry |
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| Gene name |
ARSA, MLD
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| Definition |
arylsulfatase A (EC:3.1.6.8)
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| Orthology |
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| Organism |
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| Pathway |
| Sphingolipid metabolism | | Lysosome |
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| Disease |
| Metachromatic leukodystrophy (MLD) |
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| Class |
Metabolism; Lipid metabolism; Sphingolipid metabolism [PATH: hsa00600]
Cellular Processes; Transport and catabolism; Lysosome [PATH: hsa04142]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: UniProt: |
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| Structure |
PDB: |
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| Position |
22q13.33
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| AA seq |
509 aa  
MSMGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLR
FTDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLT
GMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVP
IPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSF
AERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLL
RCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDL
SPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASS
SLTAHEPPLLYDLSKDPGENYNLLGGVAGATPEVLQALKQLQLLKAQLDAAVTFGPSQVA
RGEDPALQICCHPGCTPRPACCHCPDPHA |
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| NT seq |
1530 nt  +upstreamnt +downstreamnt
atgtccatgggggcaccgcggtccctcctcctggccctggctgctggcctggccgttgcc
cgtccgcccaacatcgtgctgatctttgccgacgacctcggctatggggacctgggctgc
tatgggcaccccagctctaccactcccaacctggaccagctggcggcgggagggctgcgg
ttcacagacttctacgtgcctgtgtctctgtgcacaccctctagggccgccctcctgacc
ggccggctcccggttcggatgggcatgtaccctggcgtcctggtgcccagctcccggggg
ggcctgcccctggaggaggtgaccgtggccgaagtcctggctgcccgaggctacctcaca
ggaatggccggcaagtggcaccttggggtggggcctgagggggccttcctgcccccccat
cagggcttccatcgatttctaggcatcccgtactcccacgaccagggcccctgccagaac
ctgacctgcttcccgccggccactccttgcgacggtggctgtgaccagggcctggtcccc
atcccactgttggccaacctgtccgtggaggcgcagcccccctggctgcccggactagag
gcccgctacatggctttcgcccatgacctcatggccgacgcccagcgccaggatcgcccc
ttcttcctgtactatgcctctcaccacacccactaccctcagttcagtgggcagagcttt
gcagagcgttcaggccgcgggccatttggggactccctgatggagctggatgcagctgtg
gggaccctgatgacagccataggggacctggggctgcttgaagagacgctggtcatcttc
actgcagacaatggacctgagaccatgcgtatgtcccgaggcggctgctccggtctcttg
cggtgtggaaagggaacgacctacgagggcggtgtccgagagcctgccttggccttctgg
ccaggtcatatcgctcccggcgtgacccacgagctggccagctccctggacctgctgcct
accctggcagccctggctggggccccactgcccaatgtcaccttggatggctttgacctc
agccccctgctgctgggcacaggcaagagccctcggcagtctctcttcttctacccgtcc
tacccagacgaggtccgtggggtttttgctgtgcggactggaaagtacaaggctcacttc
ttcacccagggctctgcccacagtgataccactgcagaccctgcctgccacgcctccagc
tctctgactgctcatgagcccccgctgctctatgacctgtccaaggaccctggtgagaac
tacaacctgctggggggtgtggccggggccaccccagaggtgctgcaagccctgaaacag
cttcagctgctcaaggcccagttagacgcagctgtgaccttcggccccagccaggtggcc
cggggcgaggaccccgccctgcagatctgctgtcatcctggctgcaccccccgcccagct
tgctgccattgcccagatccccatgcctga |
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