KEGG   Homo sapiens (human): 4126Help
Entry
4126              CDS       T01001                                 

Gene name
MANBA, MANB1
Definition
mannosidase, beta A, lysosomal (EC:3.2.1.25)
Orthology
K01192  
beta-mannosidase [EC:3.2.1.25]
Organism
hsa  Homo sapiens (human)
Pathway
Other glycan degradation
Lysosome
Disease
H00140  
beta-Mannosidosis
H00422  
Glycoproteinoses
Class
Metabolism; Glycan biosynthesis and metabolism; Other glycan degradation [PATH:hsa00511]
Cellular Processes; Transport and catabolism; Lysosome [PATH:hsa04142]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
4q24
AA seq 879 aa AA seqDB search
MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQD
SYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETD
NMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNF
VRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFD
VVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTG
YNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPA
DSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACA
LYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKD
YVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDC
WNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAG
LHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLN
DIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSV
RVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHE
LLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFS
DNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTSLTDIY
NT seq 2640 nt NT seq  +upstreamnt  +downstreamnt
atgcgcctccacctgctcctgctgctcgcgctgtgcggtgcaggcaccaccgccgcggag
ctcagttacagcttgcgtggcaactggagcatctgcaatgggaacggctcgctggagctg
cccggggcggtccctggctgcgtgcacagcgccttgttccagcagggcctgatccaggat
tcttactacagatttaatgaccttaactacagatgggtctctttggataactggacctat
agcaaagaatttaaaatcccctttgaaattagcaaatggcaaaaagtaaatttgattctt
gagggagtggatacggtttcaaaaatcctgttcaatgaagtcactattggggaaacagac
aatatgttcaatagatatagctttgatattaccaacgtggtcagggacgtgaactccatt
gagctgcgtttccagtcagcggtgttgtatgcagcacagcagagcaaagctcacactcgc
taccaggttcccccagactgccctccacttgtgcagaagggtgaatgccatgtcaacttt
gttcggaaggagcaatgttcctttagttgggactgggggccttcctttcctacccaggga
atctggaaagatgttagaattgaagcctataatatttgtcacctgaactacttcacattt
tccccaatatatgataagagtgcccaggagtggaatctggaaatagagtctacatttgat
gttgtcagctcaaagccagttggtggtcaagtgatcgtagccatccctaagttgcaaaca
caacagacatacagcattgaacttcaacctgggaaaaggattgttgagctatttgtgaac
attagcaagaatattactgtagaaacttggtggcctcatggacatggaaaccagactggg
tacaacatgactgttctttttgaactggatggaggcttaaatattgaaaaatcagctaag
gtttattttaggacagtggaacttatagaagagcctataaaagggtctcctggtttgagt
ttctatttcaaaattaatggatttcccatatttctaaaaggctcaaactggatcccagca
gattcattccaggaccgagtaacctctgagttgttacggctccttttacagtctgttgtg
gatgctaatatgaatactcttcgggtttggggaggaggaatttatgagcaggatgaattc
tatgaactctgtgatgaactaggaataatggtatggcaggattttatgtttgcctgtgcc
ctttatccaactgatcagggcttcctggattcagtgacagcagaagttgcctaccagatc
aagagactgaaatctcatccttctatcatcatatggagtggcaataatgaaaatgaggag
gcgctgatgatgaattggtatcatatcagtttcactgaccggccaatctacatcaaggac
tatgtgacactctatgtgaaaaacatcagagagctcgtactggcaggagacaagagtcgt
ccttttattacgtccagtcctacaaatggggctgaaactgttgcagaagcctgggtctct
caaaaccctaatagcaattattttggtgatgtacatttttatgactatatcagtgattgc
tggaactggaaagttttcccaaaagctcgatttgcatctgaatatggatatcagtcctgg
ccgtccttcagtacattagaaaaggtctcgtctacagaggactggtctttcaatagcaag
ttttcacttcatcgacaacatcacgaaggtggtaacaaacaaatgctttatcaggctgga
cttcatttcaaactcccccaaagcacagatccattacgcacatttaaagataccatctac
cttactcaggtgatgcaggcccagtgtgtcaaaacagaaactgaattctaccgccgtagt
cgcagcgagatagtggatcagcaagggcacacgatgggggcactttattggcagttgaat
gacatctggcaagctccttcctgggcttctcttgagtacggaggaaagtggaaaatgctt
cattactttgctcagaatttctttgctccactgttgccagtaggctttgagaatgaaaac
acgttctatatctatggtgtgtcagatcttcactcggattattcgatgacactcagtgtg
agagtccatacatggagctccctggagcccgtgtgctctcgtgtgactgaacgttttgtg
atgaaaggaggagaggctgtctgcctttatgaggagccagtgtctgaattgctgaggaga
tgtgggaattgcacacgggaaagctgtgtggtttccttttacctttcagctgaccatgaa
ctcctgagcccgaccaactaccacttcttgtcctcaccgaaggaggccgtggggctctgc
aaggcgcagatcactgccatcatctctcagcaaggtgacatatttgtttttgacctggag
acctcagctgtcgctccctttgtttggttggatgtaggaagcatcccagggagatttagt
gacaatggtttcctcatgactgagaagacacgaactatattattttacccttgggagccc
accagcaagaatgagttggagcaatcttttcatgtgacctccttaacagatatttactga

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