KEGG T01001: 4126

Homo sapiens (human): 4126

Entry

4126 CDS T01001

Gene name

MANBA, MANB1

Definition

mannosidase, beta A, lysosomal (EC:3.2.1.25)

Orthology

K01192

beta-mannosidase [EC:3.2.1.25]

Organism

hsa Homo sapiens (human)

Pathway

hsa00511	Other glycan degradation
hsa04142	Lysosome

Disease

H00140

beta-Mannosidosis

Class

Metabolism; Glycan biosynthesis and metabolism; Other glycan degradation [PATH:hsa00511]
Cellular Processes; Transport and catabolism; Lysosome [PATH:hsa04142]

SSDB

Motif

Pfam:

Glyco_hydro_2_N Glyco_hydro_2_C DUF4131 PTPLA

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

4q22-q25

AA seq 879 aa
MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQD
SYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETD
NMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNF
VRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFD
VVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTG
YNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPA
DSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACA
LYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKD
YVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDC
WNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAG
LHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLN
DIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSV
RVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHE
LLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFS
DNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTSLTDIY

NT seq 2640 nt +upstreamnt +downstreamnt
atgcgcctccacctgctcctgctgctcgcgctgtgcggtgcaggcaccaccgccgcggag
ctcagttacagcttgcgtggcaactggagcatctgcaatgggaacggctcgctggagctg
cccggggcggtccctggctgcgtgcacagcgccttgttccagcagggcctgatccaggat
tcttactacagatttaatgaccttaactacagatgggtctctttggataactggacctat
agcaaagaatttaaaatcccctttgaaattagcaaatggcaaaaagtaaatttgattctt
gagggagtggatacggtttcaaaaatcctgttcaatgaagtcactattggggaaacagac
aatatgttcaatagatatagctttgatattaccaacgtggtcagggacgtgaactccatt
gagctgcgtttccagtcagcggtgttgtatgcagcacagcagagcaaagctcacactcgc
taccaggttcccccagactgccctccacttgtgcagaagggtgaatgccatgtcaacttt
gttcggaaggagcaatgttcctttagttgggactgggggccttcctttcctacccaggga
atctggaaagatgttagaattgaagcctataatatttgtcacctgaactacttcacattt
tccccaatatatgataagagtgcccaggagtggaatctggaaatagagtctacatttgat
gttgtcagctcaaagccagttggtggtcaagtgatcgtagccatccctaagttgcaaaca
caacagacatacagcattgaacttcaacctgggaaaaggattgttgagctatttgtgaac
attagcaagaatattactgtagaaacttggtggcctcatggacatggaaaccagactggg
tacaacatgactgttctttttgaactggatggaggcttaaatattgaaaaatcagctaag
gtttattttaggacagtggaacttatagaagagcctataaaagggtctcctggtttgagt
ttctatttcaaaattaatggatttcccatatttctaaaaggctcaaactggatcccagca
gattcattccaggaccgagtaacctctgagttgttacggctccttttacagtctgttgtg
gatgctaatatgaatactcttcgggtttggggaggaggaatttatgagcaggatgaattc
tatgaactctgtgatgaactaggaataatggtatggcaggattttatgtttgcctgtgcc
ctttatccaactgatcagggcttcctggattcagtgacagcagaagttgcctaccagatc
aagagactgaaatctcatccttctatcatcatatggagtggcaataatgaaaatgaggag
gcgctgatgatgaattggtatcatatcagtttcactgaccggccaatctacatcaaggac
tatgtgacactctatgtgaaaaacatcagagagctcgtactggcaggagacaagagtcgt
ccttttattacgtccagtcctacaaatggggctgaaactgttgcagaagcctgggtctct
caaaaccctaatagcaattattttggtgatgtacatttttatgactatatcagtgattgc
tggaactggaaagttttcccaaaagctcgatttgcatctgaatatggatatcagtcctgg
ccgtccttcagtacattagaaaaggtctcgtctacagaggactggtctttcaatagcaag
ttttcacttcatcgacaacatcacgaaggtggtaacaaacaaatgctttatcaggctgga
cttcatttcaaactcccccaaagcacagatccattacgcacatttaaagataccatctac
cttactcaggtgatgcaggcccagtgtgtcaaaacagaaactgaattctaccgccgtagt
cgcagcgagatagtggatcagcaagggcacacgatgggggcactttattggcagttgaat
gacatctggcaagctccttcctgggcttctcttgagtacggaggaaagtggaaaatgctt
cattactttgctcagaatttctttgctccactgttgccagtaggctttgagaatgaaaac
acgttctatatctatggtgtgtcagatcttcactcggattattcgatgacactcagtgtg
agagtccatacatggagctccctggagcccgtgtgctctcgtgtgactgaacgttttgtg
atgaaaggaggagaggctgtctgcctttatgaggagccagtgtctgaattgctgaggaga
tgtgggaattgcacacgggaaagctgtgtggtttccttttacctttcagctgaccatgaa
ctcctgagcccgaccaactaccacttcttgtcctcaccgaaggaggccgtggggctctgc
aaggcgcagatcactgccatcatctctcagcaaggtgacatatttgtttttgacctggag
acctcagctgtcgctccctttgtttggttggatgtaggaagcatcccagggagatttagt
gacaatggtttcctcatgactgagaagacacgaactatattattttacccttgggagccc
accagcaagaatgagttggagcaatcttttcatgtgacctccttaacagatatttactga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
Protein domain (4)   
   Pfam (4)   
All databases (48)   

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