KEGG   Homo sapiens (human): 4144Help
Entry
4144              CDS       T01001                                 

Gene name
MAT2A, MATA2, MATII, SAMS2
Definition
methionine adenosyltransferase II, alpha (EC:2.5.1.6)
Orthology
K00789  
S-adenosylmethionine synthetase [EC:2.5.1.6]
Organism
hsa  Homo sapiens (human)
Pathway
Cysteine and methionine metabolism
Metabolic pathways
Biosynthesis of amino acids
Module
Methionine salvage pathway
Methionine degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01230 Biosynthesis of amino acids
    4144 (MAT2A)
  Amino acid metabolism
   00270 Cysteine and methionine metabolism
    4144 (MAT2A)
Enzymes [BR:hsa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.6  methionine adenosyltransferase
     4144 (MAT2A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
2p11.2
AA seq 395 aa AA seqDB search
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
NT seq 1188 nt NT seq  +upstreamnt  +downstreamnt
atgaacggacagctcaacggcttccacgaggcgttcatcgaggagggcacattccttttc
acctcagagtcggtcggggaaggccacccagataagatttgtgaccaaatcagtgatgct
gtccttgatgcccaccttcagcaggatcctgatgccaaagtagcttgtgaaactgttgct
aaaactggaatgatccttcttgctggggaaattacatccagagctgctgttgactaccag
aaagtggttcgtgaagctgttaaacacattggatatgatgattcttccaaaggttttgac
tacaagacttgtaacgtgctggtagccttggagcaacagtcaccagatattgctcaaggt
gttcatcttgacagaaatgaagaagacattggtgctggagaccagggcttaatgtttggc
tatgccactgatgaaactgaggagtgtatgcctttaaccattgtcttggcacacaagcta
aatgccaaactggcagaactacgccgtaatggcactttgccttggttacgccctgattct
aaaactcaagttactgtgcagtatatgcaggatcgaggtgctgtgcttcccatcagagtc
cacacaattgttatatctgttcagcatgatgaagaggtttgtcttgatgaaatgagggat
gccctaaaggagaaagtcatcaaagcagttgtgcctgcgaaataccttgatgaggataca
atctaccacctacagccaagtggcagatttgttattggtgggcctcagggtgatgctggt
ttgactggacgcaaaatcattgtggacacttatggcggttggggtgctcatggaggaggt
gccttttcaggaaaggattataccaaggtcgaccgttcagctgcttatgctgctcgttgg
gtggcaaaatcccttgttaaaggaggtctgtgccggagggttcttgttcaggtctcttat
gctattggagtttctcatccattatctatctccattttccattatggtacctctcagaag
agtgagagagagctattagagattgtgaagaagaatttcgatctccgccctggggtcatt
gtcagggatctggatctgaagaagccaatttatcagaggactgcagcctatggccacttt
ggtagggacagcttcccatgggaagtgcccaaaaagcttaaatattga

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