KEGG T01001: 4144

Homo sapiens (human): 4144

Entry

4144 CDS T01001

Gene name

MAT2A, MATA2, MATII, SAMS2

Definition

methionine adenosyltransferase II, alpha (EC:2.5.1.6)

Orthology

K00789

S-adenosylmethionine synthetase [EC:2.5.1.6]

Organism

hsa Homo sapiens (human)

Pathway

hsa00270	Cysteine and methionine metabolism
hsa01100	Metabolic pathways

Module

hsa_M00034	Methionine salvage pathway
hsa_M00035	Methionine degradation

Class

Metabolism; Amino acid metabolism; Cysteine and methionine metabolism [PATH:hsa00270]

SSDB

Motif

Pfam:

S-AdoMet_synt_C S-AdoMet_synt_M S-AdoMet_synt_N AdoMet_Synthase

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2P02

Position

2p11.2

AA seq 395 aa
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY

NT seq 1188 nt +upstreamnt +downstreamnt
atgaacggacagctcaacggcttccacgaggcgttcatcgaggagggcacattccttttc
acctcagagtcggtcggggaaggccacccagataagatttgtgaccaaatcagtgatgct
gtccttgatgcccaccttcagcaggatcctgatgccaaagtagcttgtgaaactgttgct
aaaactggaatgatccttcttgctggggaaattacatccagagctgctgttgactaccag
aaagtggttcgtgaagctgttaaacacattggatatgatgattcttccaaaggttttgac
tacaagacttgtaacgtgctggtagccttggagcaacagtcaccagatattgctcaaggt
gttcatcttgacagaaatgaagaagacattggtgctggagaccagggcttaatgtttggc
tatgccactgatgaaactgaggagtgtatgcctttaaccattgtcttggcacacaagcta
aatgccaaactggcagaactacgccgtaatggcactttgccttggttacgccctgattct
aaaactcaagttactgtgcagtatatgcaggatcgaggtgctgtgcttcccatcagagtc
cacacaattgttatatctgttcagcatgatgaagaggtttgtcttgatgaaatgagggat
gccctaaaggagaaagtcatcaaagcagttgtgcctgcgaaataccttgatgaggataca
atctaccacctacagccaagtggcagatttgttattggtgggcctcagggtgatgctggt
ttgactggacgcaaaatcattgtggacacttatggcggttggggtgctcatggaggaggt
gccttttcaggaaaggattataccaaggtcgaccgttcagctgcttatgctgctcgttgg
gtggcaaaatcccttgttaaaggaggtctgtgccggagggttcttgttcaggtctcttat
gctattggagtttctcatccattatctatctccattttccattatggtacctctcagaag
agtgagagagagctattagagattgtgaagaagaatttcgatctccgccctggggtcatt
gtcagggatctggatctgaagaagccaatttatcagaggactgcagcctatggccacttt
ggtagggacagcttcccatgggaagtgcccaaaaagcttaaatattga

All links

Pathway (4)   
   KEGG PATHWAY (2)   
   KEGG MODULE (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (12)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (33)   
   RefSeq(nuc) (1)   
   GenBank (16)   
   EMBL (16)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (78)   

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