KEGG   Homo sapiens (human): 4190Help
Entry
4190              CDS       T01001                                 

Gene name
MDH1, HEL-S-32, MDH-s, MDHA, MGC:1375, MOR2
Definition
(RefSeq) malate dehydrogenase 1
  KO
K00025  
malate dehydrogenase [EC:1.1.1.37]
Organism
hsa  Homo sapiens (human)
Pathway
Citrate cycle (TCA cycle)
Cysteine and methionine metabolism
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Metabolic pathways
Carbon metabolism
Proximal tubule bicarbonate reclamation
Module
Citrate cycle (TCA cycle, Krebs cycle)
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    4190 (MDH1)
  Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    4190 (MDH1)
   00620 Pyruvate metabolism
    4190 (MDH1)
   00630 Glyoxylate and dicarboxylate metabolism
    4190 (MDH1)
  Amino acid metabolism
   00270 Cysteine and methionine metabolism
    4190 (MDH1)
 Organismal Systems
  Excretory system
   04964 Proximal tubule bicarbonate reclamation
    4190 (MDH1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.37  malate dehydrogenase
     4190 (MDH1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
2p13.3
AA seq 334 aa AA seqDB search
MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC
ALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYA
KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKN
VIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKL
SSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFV
EGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
NT seq 1005 nt NT seq  +upstreamnt  +downstreamnt
atgtctgaaccaatcagagtccttgtgactggagcagctggtcaaattgcatattcactg
ctgtacagtattggaaatggatctgtctttggtaaagatcagcctataattcttgtgctg
ttggatatcacccccatgatgggtgtcctggacggtgtcctaatggaactgcaagactgt
gcccttcccctcctgaaagatgtcatcgcaacagataaagaagacgttgccttcaaagac
ctggatgtggccattcttgtgggctccatgccaagaagggaaggcatggagagaaaagat
ttactgaaagcaaatgtgaaaatcttcaaatcccagggtgcagccttagataaatacgcc
aagaagtcagttaaggttattgttgtgggtaatccagccaataccaactgcctgactgct
tccaagtcagctccatccatccccaaggagaacttcagttgcttgactcgtttggatcac
aaccgagctaaagctcaaattgctcttaaacttggtgtgactgctaatgatgtaaagaat
gtcattatctggggaaaccattcctcgactcagtatccagatgtcaaccatgccaaggtg
aaattgcaaggaaaggaagttggtgtttatgaagctctgaaagatgacagctggctcaag
ggagaatttgtcacgactgtgcagcagcgtggcgctgctgtcatcaaggctcgaaaacta
tccagtgccatgtctgctgcaaaagccatctgtgaccacgtcagggacatctggtttgga
accccagagggagagtttgtgtccatgggtgttatctctgatggcaactcctatggtgtt
cctgatgatctgctctactcattccctgttgtaatcaagaataagacctggaagtttgtt
gaaggtctccctattaatgatttctcacgtgagaagatggatcttactgcaaaggaactg
acagaagaaaaagaaagtgcttttgaatttctttcctctgcctga

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