KEGG   Homo sapiens (human): 427Help
Entry
427               CDS       T01001                                 

Gene name
ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME
Definition
(RefSeq) N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23)
  KO
K12348  
acid ceramidase [EC:3.5.1.23]
Organism
hsa  Homo sapiens (human)
Pathway
Sphingolipid metabolism
Metabolic pathways
Sphingolipid signaling pathway
Lysosome
Module
Sphingosine biosynthesis
Disease
H00138  
Farber lipogranulomatosis
H00424  
Defects in the degradation of sphingomyelin
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    427 (ASAH1)
 Environmental Information Processing
  Signal transduction
   04071 Sphingolipid signaling pathway
    427 (ASAH1)
 Cellular Processes
  Transport and catabolism
   04142 Lysosome
    427 (ASAH1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.23  ceramidase
     427 (ASAH1)
Peptidases [BR:hsa01002]
 Cysteine Peptidases
  Family C89
   427 (ASAH1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   427 (ASAH1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
8p22
AA seq 389 aa AA seqDB search
MNCCIGLGEKARGSHRASYPSLSALFTEASILGFGSFAVKAQWTEDCRKSTYPPSGPTVF
PAVIRYRGAVPWYTINLDLPPYKRWHELMLDKAPVPGLLGNFPGPFEEEMKGIAAVTDIP
LGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLT
VNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDV
MWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYE
LDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVLNK
LTVYTTLIDVTKGQFETYLRDCPDPCIGW
NT seq 1170 nt NT seq  +upstreamnt  +downstreamnt
atgaactgctgcatcgggctgggagagaaagctcgcgggtcccaccgggcctcctaccca
agtctcagcgcgcttttcaccgaggcctcaattctgggatttggcagctttgctgtgaaa
gcccaatggacagaggactgcagaaaatcaacctatcctccttcaggaccaactgtcttc
cctgctgttataaggtacagaggtgcagttccatggtacaccataaatcttgacttacca
ccctacaaaagatggcatgaattgatgcttgacaaggcaccagtgcctggcctacttggc
aactttcctggcccttttgaagaggaaatgaagggtattgccgctgttactgatatacct
ttaggagagattatttcattcaatattttttatgaattatttaccatttgtacttcaata
gtagcagaagacaaaaaaggtcatctaatacatgggagaaacatggattttggagtattt
cttgggtggaacataaataatgatacctgggtcataactgagcaactaaaacctttaaca
gtgaatttggatttccaaagaaacaacaaaactgtcttcaaggcttcaagctttgctggc
tatgtgggcatgttaacaggattcaaaccaggactgttcagtcttacactgaatgaacgt
ttcagtataaatggtggttatctgggtattctagaatggattctgggaaagaaagatgtc
atgtggatagggttcctcactagaacagttctggaaaatagcacaagttatgaagaagcc
aagaatttattgaccaagaccaagatattggccccagcctactttatcctgggaggcaac
cagtctggggaaggttgtgtgattacacgagacagaaaggaatcattggatgtatatgaa
ctcgatgctaagcagggtagatggtatgtggtacaaacaaattatgaccgttggaaacat
cccttcttccttgatgatcgcagaacgcctgcaaagatgtgtctgaaccgcaccagccaa
gagaatatctcatttgaaaccatgtatgatgtcctgtcaacaaaacctgtcctcaacaag
ctgaccgtatacacaaccttgatagatgttaccaaaggtcaattcgaaacttacctgcgg
gactgccctgacccttgtataggttggtga

DBGET integrated database retrieval system