KEGG T01001: 4297

Homo sapiens (human): 4297

Entry

4297 CDS T01001

Gene name

MLL, ALL-1, CXXC7, HRX, HTRX1, KMT2A, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS

Definition

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) (EC:2.1.1.43)

Orthology

K09186

histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43]

Organism

hsa Homo sapiens (human)

Pathway

hsa00310	Lysine degradation
hsa05202	Transcriptional misregulation in cancer

Disease

H00001	Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
H00002	Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)

Class

Metabolism; Amino acid metabolism; Lysine degradation [PATH:hsa00310]
Human Diseases; Cancers; Transcriptional misregulation in cancers [PATH:hsa05202]

SSDB

Motif

Pfam:

FYRC SET FYRN PHD zf-HC5HC2H zf-CXXC zf-HC5HC2H_2 PHD_2 Bromodomain

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3LQH 3LQJ 3LQI 2W5Y 2W5Z 3U88 2KYU 2KKF 2JYI 2J2S 2AGH

Position

11q23

AA seq 3972 aa
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAV
AAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSA
AIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKD
ISELPKGNKEDSLKKIKRTPSATFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIV
RRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSR
IIKTPRRFIEDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSS
SPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPAS
TAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPED
VGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSL
SISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFT
PGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKI
LIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTD
KRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKA
PQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWM
PSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVP
KTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNIL
STLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASS
GHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNK
CRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCA
KLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYEILSNLPESV
AYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETE
ESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAA
INSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPS
LDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSRED
SPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGS
LKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRH
RDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDL
SDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAH
SPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSP
GCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGN
TYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKN
SHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHN
TTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDT
EVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEE
GNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRK
RTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNN
TSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGV
RSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERL
ASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDR
PEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSD
KNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNL
GEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTR
SPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQG
HMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPS
QISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMET
NTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNI
SNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPS
STPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFE
PAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSAS
VPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPST
AAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASG
PQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPK
PKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVE
QSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRK
ESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGL
RMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDM
FNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSP
IHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATM
HGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPC
NCGAKKCRKFLN

NT seq 11919 nt +upstreamnt +downstreamnt
atggcgcacagctgtcggtggcgcttccccgcccgacccgggaccaccgggggcggcggc
ggcggggggcgccggggcctagggggcgccccgcggcaacgcgtcccggccctgctgctt
ccccccgggcccccggtcggcggtggcggccccggggcgcccccctcccccccggctgtg
gcggccgcggcggcggcggcgggaagcagcggggctggggttccagggggagcggccgcc
gcctcagcagcctcctcgtcgtccgcctcgtcttcgtcttcgtcatcgtcctcagcctct
tcagggccggccctgctccgggtgggcccgggcttcgacgcggcgctgcaggtctcggcc
gccatcggcaccaacctgcgccggttccgggccgtgtttggggagagcggcgggggaggc
ggcagcggagaggatgagcaattcttaggttttggctcagatgaagaagtcagagtgcga
agtcccacaaggtctccttcagttaaaactagtcctcgaaaacctcgtgggagacctaga
agtggctctgaccgaaattcagctatcctctcagatccatctgtgttttcccctctaaat
aaatcagagaccaaatctggagataagatcaagaagaaagattctaaaagtatagaaaag
aagagaggaagacctcccaccttccctggagtaaaaatcaaaataacacatggaaaggac
atttcagagttaccaaagggaaacaaagaagatagcctgaaaaaaattaaaaggacacct
tctgctacgtttcagcaagccacaaagattaaaaaattaagagcaggtaaactctctcct
ctcaagtctaagtttaagacagggaagcttcaaataggaaggaagggggtacaaattgta
cgacggagaggaaggcctccatcaacagaaaggataaagaccccttcgggtctcctcatt
aattctgaactggaaaagccccagaaagtccggaaagacaaggaaggaacacctccactt
acaaaagaagataagacagttgtcagacaaagccctcgaaggattaagccagttaggatt
attccttcttcaaaaaggacagatgcaaccattgctaagcaactcttacagagggcaaaa
aagggggctcaaaagaaaattgaaaaagaagcagctcagctgcagggaagaaaggtgaag
acacaggtcaaaaatattcgacagttcatcatgcctgttgtcagtgctatctcctcgcgg
atcattaagacccctcggcggtttatagaggatgaggattatgaccctccaattaaaatt
gcccgattagagtctacaccgaatagtagattcagtgccccgtcctgtggatcttctgaa
aaatcaagtgcagcttctcagcactcctctcaaatgtcttcagactcctctcgatctagt
agccccagtgttgatacctccacagactctcaggcttctgaggagattcaggtacttcct
gaggagcggagcgatacccctgaagttcatcctccactgcccatttcccagtccccagaa
aatgagagtaatgataggagaagcagaaggtattcagtgtcggagagaagttttggatct
agaacgacgaaaaaattatcaactctacaaagtgccccccagcagcagacctcctcgtct
ccacctccacctctgctgactccaccgccaccactgcagccagcctccagtatctctgac
cacacaccttggcttatgcctccaacaatccccttagcatcaccatttttgcctgcttcc
actgctcctatgcaagggaagcgaaaatctattttgcgagaaccgacatttaggtggact
tctttaaagcattctaggtcagagccacaatacttttcctcagcaaagtatgccaaagaa
ggtcttattcgcaaaccaatatttgataatttccgaccccctccactaactcccgaggac
gttggctttgcatctggtttttctgcatctggtaccgctgcttcagcccgattgttttcg
ccactccattctggaacaaggtttgatatgcacaaaaggagccctcttctgagagctcca
agatttactccaagtgaggctcactctagaatatttgagtctgtaaccttgcctagtaat
cgaacttctgctggaacatcttcttcaggagtatccaatagaaaaaggaaaagaaaagtg
tttagtcctattcgatctgaaccaagatctccttctcactccatgaggacaagaagtgga
aggcttagtagttctgagctctcacctctcacccccccgtcttctgtctcttcctcgtta
agcatttctgttagtcctcttgccactagtgccttaaacccaacttttacttttccttct
cattccctgactcagtctggggaatctgcagagaaaaatcagagaccaaggaagcagact
agtgctccggcagagccattttcatcaagtagtcctactcctctcttcccttggtttacc
ccaggctctcagactgaaagagggagaaataaagacaaggcccccgaggagctgtccaaa
gatcgagatgctgacaagagcgtggagaaggacaagagtagagagagagaccgggagaga
gaaaaggagaataagcgggagtcaaggaaagagaaaaggaaaaagggatcagaaattcag
agtagttctgctttgtatcctgtgggtagggtttccaaagagaaggttgttggtgaagat
gttgccacttcatcttctgccaaaaaagcaacagggcggaagaagtcttcatcacatgat
tctgggactgatattacttctgtgactcttggggatacaacagctgtcaaaaccaaaata
cttataaagaaagggagaggaaatctggaaaaaaccaacttggacctcggcccaactgcc
ccatccctggagaaggagaaaaccctctgcctttccactccttcatctagcactgttaaa
cattccacttcctccataggctccatgttggctcaggcagacaagcttccaatgactgac
aagagggttgccagcctcctaaaaaaggccaaagctcagctctgcaagattgagaagagt
aagagtcttaaacaaaccgaccagcccaaagcacagggtcaagaaagtgactcatcagag
acctctgtgcgaggaccccggattaaacatgtctgcagaagagcagctgttgcccttggc
cgaaaacgagctgtgtttcctgatgacatgcccaccctgagtgccttaccatgggaagaa
cgagaaaagattttgtcttccatggggaatgatgacaagtcatcaattgctggctcagaa
gatgctgaacctcttgctccacccatcaaaccaattaaacctgtcactagaaacaaggca
ccccaggaacctccagtaaagaaaggacgtcgatcgaggcggtgtgggcagtgtcccggc
tgccaggtgcctgaggactgtggtgtttgtactaattgcttagataagcccaagtttggt
ggtcgcaatataaagaagcagtgctgcaagatgagaaaatgtcagaatctacaatggatg
ccttccaaagcctacctgcagaagcaagctaaagctgtgaaaaagaaagagaaaaagtct
aagaccagtgaaaagaaagacagcaaagagagcagtgttgtgaagaacgtggtggactct
agtcagaaacctaccccatcagcaagagaggatcctgccccaaagaaaagcagtagtgag
cctcctccacgaaagcccgtcgaggaaaagagtgaagaagggaatgtctcggcccctggg
cctgaatccaaacaggccaccactccagcttccaggaagtcaagcaagcaggtctcccag
ccagcactggtcatcccgcctcagccacctactacaggaccgccaagaaaagaagttccc
aaaaccactcctagtgagcccaagaaaaagcagcctccaccaccagaatcaggtccagag
cagagcaaacagaaaaaagtggctccccgcccaagtatccctgtaaaacaaaaaccaaaa
gaaaaggaaaaaccacctccggtcaataagcaggagaatgcaggcactttgaacatcctc
agcactctctccaatggcaatagttctaagcaaaaaattccagcagatggagtccacagg
atcagagtggactttaaggaggattgtgaagcagaaaatgtgtgggagatgggaggctta
ggaatcttgacttctgttcctataacacccagggtggtttgctttctctgtgccagtagt
gggcatgtagagtttgtgtattgccaagtctgttgtgagcccttccacaagttttgttta
gaggagaacgagcgccctctggaggaccagctggaaaattggtgttgtcgtcgttgcaaa
ttctgtcacgtttgtggaaggcaacatcaggctacaaagcagctgctggagtgtaataag
tgccgaaacagctatcaccctgagtgcctgggaccaaactaccccaccaaacccacaaag
aagaagaaagtctggatctgtaccaagtgtgttcgctgtaagagctgtggatccacaact
ccaggcaaagggtgggatgcacagtggtctcatgatttctcactgtgtcatgattgcgcc
aagctctttgctaaaggaaacttctgccctctctgtgacaaatgttatgatgatgatgac
tatgagagtaagatgatgcaatgtggaaagtgtgatcgctgggtccattccaaatgtgag
aatctttcaggtacagaagatgagatgtatgagattctatctaatctgccagaaagtgtg
gcctacacttgtgtgaactgtactgagcggcaccctgcagagtggcgactggcccttgaa
aaagagctgcagatttctctgaagcaagttctgacagctttgttgaattctcggactacc
agccatttgctacgctaccggcaggctgccaagcctccagacttaaatcccgagacagag
gagagtataccttcccgcagctcccccgaaggacctgatccaccagttcttactgaggtc
agcaaacaggatgatcagcagcctttagatctagaaggagtcaagaggaagatggaccaa
gggaattacacatctgtgttggagttcagtgatgatattgtgaagatcattcaagcagcc
attaattcagatggaggacagccagaaattaaaaaagccaacagcatggtcaagtccttc
ttcattcggcaaatggaacgtgtttttccatggttcagtgtcaaaaagtccaggttttgg
gagccaaataaagtatcaagcaacagtgggatgttaccaaacgcagtgcttccaccttca
cttgaccataattatgctcagtggcaggagcgagaggaaaacagccacactgagcagcct
cctttaatgaagaaaatcattccagctcccaaacccaaaggtcctggagaaccagactca
ccaactcctctgcatcctcctacaccaccaattttgagtactgataggagtcgagaagac
agtccagagctgaacccacccccaggcatagaagacaatagacagtgtgcgttatgtttg
acttatggtgatgacagtgctaatgatgctggtcgtttactatatattggccaaaatgag
tggacacatgtaaattgtgctttgtggtcagcggaagtgtttgaagatgatgacggatca
ctaaagaatgtgcatatggctgtgatcaggggcaagcagctgagatgtgaattctgccaa
aagccaggagccaccgtgggttgctgtctcacatcctgcaccagcaactatcacttcatg
tgttcccgagccaagaactgtgtctttctggatgataaaaaagtatattgccaacgacat
cgggatttgatcaaaggcgaagtggttcctgagaatggatttgaagttttcagaagagtg
tttgtggactttgaaggaatcagcttgagaaggaagtttctcaatggcttggaaccagaa
aatatccacatgatgattgggtctatgacaatcgactgcttaggaattctaaatgatctc
tccgactgtgaagataagctctttcctattggatatcagtgttccagggtatactggagc
accacagatgctcgcaagcgctgtgtatatacatgcaagatagtggagtgccgtcctcca
gtcgtagagccggatatcaacagcactgttgaacatgatgaaaacaggaccattgcccat
agtccaacatcttttacagaaagttcatcaaaagagagtcaaaacacagctgaaattata
agtcctccatcaccagaccgacctcctcattcacaaacctctggctcctgttattatcat
gtcatctcaaaggtccccaggattcgaacacccagttattctccaacacagagatcccct
ggctgtcgaccgttgccttctgcaggaagtcctaccccaaccactcatgaaatagtcaca
gtaggtgatcctttactctcctctggacttcgaagcattggctccaggcgtcacagtacc
tcttccttatcaccccagcggtccaaactccggataatgtctccaatgagaactgggaat
acttactctaggaataatgtttcctcagtctccaccaccgggaccgctactgatcttgaa
tcaagtgccaaagtagttgatcatgtcttagggccactgaattcaagtactagtttaggg
caaaacacttccacctcttcaaatttgcaaaggacagtggttactgtaggcaataaaaac
agtcacttggatggatcttcatcttcagaaatgaagcagtccagtgcttcagacttggtg
tccaagagctcctctttaaagggagagaagaccaaagtgctgagttccaagagctcagag
ggatctgcacataatgtggcttaccctggaattcctaaactggccccacaggttcataac
acaacatctagagaactgaatgttagtaaaatcggctcctttgctgaaccctcttcagtg
tcgttttcttctaaagaggccctctccttcccacacctccatttgagagggcaaaggaat
gatcgagaccaacacacagattctacccaatcagcaaactcctctccagatgaagatact
gaagtcaaaaccttgaagctatctggaatgagcaacagatcatccattatcaacgaacat
atgggatctagttccagagataggagacagaaagggaaaaaatcctgtaaagaaactttc
aaagaaaagcattccagtaaatcttttttggaacctggtcaggtgacaactggtgaggaa
ggaaacttgaagccagagtttatggatgaggttttgactcctgagtatatgggccaacga
ccatgtaacaatgtttcttctgataagattggtgataaaggcctttctatgccaggagtc
cccaaagctccacccatgcaagtagaaggatctgccaaggaattacaggcaccacggaaa
cgcacagtcaaagtgacactgacacctctaaaaatggaaaatgagagtcaatccaaaaat
gccctgaaagaaagtagtcctgcttcccctttgcaaatagagtcaacatctcccacagaa
ccaatttcagcctctgaaaatccaggagatggtccagtggcccaaccaagccccaataat
acctcatgccaggattctcaaagtaacaactatcagaatcttccagtacaggacagaaac
ctaatgcttccagatggccccaaacctcaggaggatggctcttttaaaaggaggtatccc
cgtcgcagtgcccgtgcacgttctaacatgttttttgggcttaccccactctatggagta
agatcctatggtgaagaagacattccattctacagcagctcaactgggaagaagcgaggc
aagagatcagctgaaggacaggtggatggggccgatgacttaagcacttcagatgaagac
gacttatactattacaacttcactagaacagtgatttcttcaggtggagaggaacgactg
gcatcccataatttatttcgggaggaggaacagtgtgatcttccaaaaatctcacagttg
gatggtgttgatgatgggacagagagtgatactagtgtcacagccacaacaaggaaaagc
agccagattccaaaaagaaatggtaaagaaaatggaacagagaacttaaagattgataga
cctgaagatgctggggagaaagaacatgtcactaagagttctgttggccacaaaaatgag
ccaaagatggataactgccattctgtaagcagagttaaaacacagggacaagattccttg
gaagctcagctcagctcattggagtcaagccgcagagtccacacaagtaccccctccgac
aaaaatttactggacacctataatactgagctcctgaaatcagattcagacaataacaac
agtgatgactgtgggaatatcctgccttcagacattatggactttgtactaaagaatact
ccatccatgcaggctttgggtgagagcccagagtcatcttcatcagaactcctgaatctt
ggtgaaggattgggtcttgacagtaatcgtgaaaaagacatgggtctttttgaagtattt
tctcagcagctgcctacaacagaacctgtggatagtagtgtctcttcctctatctcagca
gaggaacagtttgagttgcctctagagctaccatctgatctgtctgtcttgaccacccgg
agtcccactgtccccagccagaatcccagtagactagctgttatctcagactcaggggag
aagagagtaaccatcacagaaaaatctgtagcctcctctgaaagtgacccagcactgctg
agcccaggagtagatccaactcctgaaggccacatgactcctgatcattttatccaagga
cacatggatgcagaccacatctctagccctccttgtggttcagtagagcaaggtcatggc
aacaatcaggatttaactaggaacagtagcacccctggccttcaggtacctgtttcccca
actgttcccatccagaaccagaagtatgtgcccaattctactgatagtcctggcccgtct
cagatttccaatgcagctgtccagaccactccaccccacctgaagccagccactgagaaa
ctcatagttgttaaccagaacatgcagccactttatgttctccaaactcttccaaatgga
gtgacccaaaaaatccaattgacctcttctgttagttctacacccagtgtgatggagaca
aatacttcagtattgggacccatgggaggtggtctcacccttaccacaggactaaatcca
agcttgccaacttctcaatctttgttcccttctgctagcaaaggattgctacccatgtct
catcaccagcacttacattccttccctgcagctactcaaagtagtttcccaccaaacatc
agcaatcctccttcaggcctgcttattggggttcagcctcctccggatccccaacttttg
gtttcagaatccagccagaggacagacctcagtaccacagtagccactccatcctctgga
ctcaagaaaagacccatatctcgtctacagacccgaaagaataaaaaacttgctccctct
agtaccccttcaaacattgccccttctgatgtggtttctaatatgacattgattaacttc
acaccctcccagcttcctaatcatccaagtctgttagatttggggtcacttaatacttca
tctcaccgaactgtccccaacatcataaaaagatctaaatctagcatcatgtattttgaa
ccggcacccctgttaccacagagtgtgggaggaactgctgccacagcggcaggcacatca
acaataagccaggatactagccacctcacatcagggtctgtgtctggcttggcatccagt
tcctctgtcttgaatgttgtatccatgcaaactaccacaacccctacaagtagtgcgtca
gttccaggacacgtcaccttaaccaacccaaggttgcttggtaccccagatattggctca
ataagcaatcttttaatcaaagctagccagcagagcctggggattcaggaccagcctgtg
gctttaccgccaagttcaggaatgtttccacaactggggacatcacagaccccctctact
gctgcaataacagcggcatctagcatctgtgtgctcccctccactcagactacgggcata
acagccgcttcaccttctggggaagcagacgaacactatcagcttcagcatgtgaaccag
ctccttgccagcaaaactgggattcattcttcccagcgtgatcttgattctgcttcaggg
ccccaggtatccaactttacccagacggtagacgctcctaatagcatgggactggagcag
aacaaggctttatcctcagctgtgcaagccagccccacctctcctgggggttctccatcc
tctccatcttctggacagcggtcagcaagcccttcagtgccgggtcccactaaacccaaa
ccaaaaaccaaacggtttcagctgcctctagacaaagggaatggcaagaagcacaaagtt
tcccatttgcggaccagttcttctgaagcacacattccagaccaagaaacgacatccctg
acctcaggcacagggactccaggagcagaggctgagcagcaggatacagctagcgtggag
cagtcctcccagaaggagtgtgggcaacctgcagggcaagtcgctgttcttccggaagtt
caggtgacccaaaatccagcaaatgaacaagaaagtgcagaacctaaaacagtggaagaa
gaggaaagtaatttcagctccccactgatgctttggcttcagcaagaacaaaagcggaag
gaaagcattactgagaaaaaacccaagaaaggacttgtttttgaaatttccagtgatgat
ggctttcagatctgtgcagaaagtattgaagatgcctggaagtcattgacagataaagtc
caggaagctcgatcaaatgcccgcctaaagcagctctcatttgcaggtgttaacggtttg
aggatgctggggattctccatgatgcagttgtgttcctcattgagcagctgtctggtgcc
aagcactgtcgaaattacaaattccgtttccacaagccagaggaggccaatgaacccccc
ttgaaccctcacggctcagccagggctgaagtccacctcaggaagtcagcatttgacatg
tttaacttcctggcttctaaacatcgtcagcctcctgaatacaaccccaatgatgaagaa
gaggaggaggtacagctgaagtcagctcggagggcaactagcatggatctgccaatgccc
atgcgcttccggcacttaaaaaagacttctaaggaggcagttggtgtctacaggtctccc
atccatggccggggtcttttctgtaagagaaacattgatgcaggtgagatggtgattgag
tatgccggcaacgtcatccgctccatccagactgacaagcgggaaaagtattacgacagc
aagggcattggttgctatatgttccgaattgatgactcagaggtagtggatgccaccatg
catggaaatgctgcacgcttcatcaatcactcgtgtgagcctaactgctattctcgggtc
atcaatattgatgggcagaagcacattgtcatctttgccatgcgtaagatctaccgagga
gaggaactcacttacgactataagttccccattgaggatgccagcaacaagctgccctgc
aactgtggcgccaagaaatgccggaagttcctaaactaa

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (25)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (69)   
   RefSeq(nuc) (3)   
   GenBank (33)   
   EMBL (33)   
3D Structure (11)   
   PDB (11)   
Protein domain (9)   
   Pfam (9)   
All databases (144)   

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