KEGG T01001: 4301

Homo sapiens (human): 4301

Entry

4301 CDS T01001

Gene name

MLLT4, AF6, RP3-431P23.3

Definition

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4

Orthology

K05702

afadin

Organism

hsa Homo sapiens (human)

Pathway

hsa04520	Adherens junction
hsa04530	Tight junction
hsa04670	Leukocyte transendothelial migration

Class

Cellular Processes; Cell communication; Adherens junction [PATH:hsa04520]
Cellular Processes; Cell communication; Tight junction [PATH:hsa04530]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:hsa04670]

SSDB

Motif

Pfam:

RA DIL PDZ FHA PDZ_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2EXG 2AIN 1XZ9 1T2M

Position

6q27

AA seq 1651 aa
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA
SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS
DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV
MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE
GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR
LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET
TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI
HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI
LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT
HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA
HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA
ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD
CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE
NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC
QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL
SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR
TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS
PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV
STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT
DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE
HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD
GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK
LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV
SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL
MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKR
EAEDRARQEEERRRQEEERTKRDAEEKVMVL

NT seq 4956 nt +upstreamnt +downstreamnt
atgtcggcgggcggccgtgacgaggagcggcggaagctggccgacatcatccaccactgg
aacgccaaccggctggacctgttcgagatcagccagccgaccgaggatttggagttccat
ggagtgatgagattttattttcaagataaagctgctggaaactttgcaacaaaatgtatt
cgggtctctagtactgccaccactcaagatgtaatcgaaacgctcgcggagaaatttcga
cctgatatgcgaatgctgtcctctcccaagtattcactctatgaagtgcatgtcagcgga
gaaagaagattggatatagatgagaaacctctagttgtacaactgaattggaacaaagat
gatcgggaaggcagatttgttcttaagaatgagaatgacgccattcctcctaagaaggct
caaagtaatggacctgaaaagcaggaaaaagaaggggttatccagaacttcaagagaact
ctctcaaagaaagaaaagaaggaaaaaaagaagagagaaaaagaggcattgcgacaggca
tctgataaagatgatagacctttccaaggggaggatgttgaaaattctcgactggctgct
gaggtttacaaagacatgccggaaaccagctttactcgaaccatttctaatcctgaggtg
gttatgaaacgacggaggcagcaaaaattggaaaagagaatgcaggaatttcggagctca
gatgggcggcctgattcaggtggaacattgagaatttatgcagatagtttaaaaccaaat
attccctacaagacaatcctgctgtctactacagatcctgcagactttgctgtggctgaa
gctttagagaagtatggtctggaaaaagaaaaccctaaggattactgcatcgcccgggtt
atgcttcctcctggagcccagcattctgatgaaaagggtgctaaagaaattattcttgat
gatgatgagtgtcctttacaaatcttcagggaatggccaagtgacaaagggattttagtc
tttcagttgaagaggaggccaccagaccacatcccaaagaaaaccaagaaacacttggaa
ggcaagacacccaagggaaaggagagagctgacgggtctggctatggctccacccttcct
ccggagaagctgccctatttagtagagttaagcccagggagaaggaatcactttgcctac
tacaactatcacacttacgaagatggttctgactctagagataagccaaagctttaccgc
cttcagttaagtgttactgaagttgggacagaaaagttggatgacaactctatccagttg
tttggcccaggaattcagccccatcactgtgaccttaccaacatggatggagtggtcact
gtgacgcccagaagtatggacgcagaaacctacgtggaaggccagcgcatctcagaaacc
accatgctgcagagtggcatgaaagtgcagtttggggcgtcccatgtatttaagtttgtg
gaccccagtcaggatcatgctcttgcaaaaagatctgtggatggaggcctgatggttaag
ggcccaagacataaacctggaattgttcaggagacaacttttgatttgggaggagatatt
catagtgggacagcattaccgacaagcaagagcaccactaggctggacagcgacagagtg
tcgtctgcctctagcacagccgagcggggaatggtgaagccgatgatcagagtagaacag
cagccagattatcgcaggcaagaaagcagaacacaggatgcttctgggcctgagctgata
ctacctgcaagcattgaattcagggaaagttctgaagattcatttttgtctgccattata
aattatactaatagctctacagtccactttaagttgtcccctacatatgtattatatatg
gcatgccggtatgtattgtccaaccagtacagacctgacatcagccctacagagcgcaca
cataaagtcattgcagtcgtcaacaagatggtgagcatgatggagggtgtcatccagaaa
cagaagaatattgcaggggcacttgccttctggatggcaaatgcatctgaacttctcaac
ttcattaagcaagaccgagaccttagtcggatcacactggatgctcaagatgttttagca
catttggttcaaatggcatttaaatacttggttcactgtcttcaatcagaacttaataat
tacatgccagcctttctagatgaccctgaagagaacagtctgcaacgaccaaaaatagat
gatgtgctgcacacgctcacaggagccatgtccttgctacgacgctgcagagtcaatgcc
gccctgaccatccagctcttctctcagctcttccacttcatcaatatgtggctgttcaat
agattggtgaccgacccagattcggggctgtgctcccattactggggtgcgattatccgt
cagcagttgggccatattgaagcctgggctgagaagcaggggctggaactggctgcggac
tgtcatctgagcaggatcgtgcaggcaacgactttgcttaccatggataagtatgcacct
gatgacattccaaatataaacagcacctgctttaagttaaattcattacaacttcaagcc
ttattacagaactatcactgtgcacctgatgagccttttatcccaacggatcttatagaa
aatgtagtgactgtggctgaaaacactgccgatgagctggcccgcagtgatggaagggaa
gtgcagttggaggaggatcctgatctgcagctgccgtttcttttgccagaagatggttat
tcttgtgatgttgtcagaaacattccaaatggtttacaagaatttttagaccctctgtgc
cagagaggattttgcaggttaattcctcacacacgttcaccaggtacttggacaatatat
tttgaaggtgcagattatgaaagtcaccttctgcgtgagaacacagagctggctcagcct
ctgaggaaagaacctgaaataatcactgtgaccctaaaaaagcagaatggaatgggcctt
agcattgttgcagcaaagggtgctggtcaagataaactaggaatctatgtgaagtcggtt
gtgaaaggaggtgctgcagatgtggatggacgtctagctgcaggtgatcagctcctcagt
gtggatggacgaagtctggttggactctctcaggaaagggcggcagaactcatgacaaga
acaagctctgtggtgacactggaagtagcaaagcagggtgccatctaccacggtctggcc
acccttctcaatcagccatcccccatgatgcagagaatttcagatcgtcgtggctcaggt
aaaccccgaccaaagagtgaaggctttgagctctataataattcaactcaaaatgggtct
cctgagagtcctcagctgccttgggcagaatatagtgaaccaaagaaattgcctggtgat
gacagactgatgaaaaatagagctgatcaccgttccagccccaacgtagcaaatcagcct
cctagtcctggagggaaaagtgcatatgcctctggaacaacagcgaagataacatctgtc
tctactggaaacctctgcactgaggagcagacgcctccgcctagacctgaagcctacccc
atccccactcagacgtacaccagagagtattttaccttcccagcttccaaatcccaggat
cggatggctcctcctcagaaccagtggccaaattatgaggaaaagccacatatgcacaca
gatagtaatcattccagtattgcaattcagcgtgttacacgttcccaagaagaacttcga
gaagataaagcttaccaacttgagcggcatcgaatagaggcagctatggaccgaaagtct
gatagtgatatgtggataaatcagagctcctcactggactccagtacctctagccaggag
catctgaaccattcctctaagtcggtcacccctgcttccacactgaccaaaagtggccct
ggccgttggaaaacaccagcagccataccggccacccctgtggccgtctcccagccaatc
cgaacagacctgcctccgccacccccgccacctccagtccactatgccggtgatttcgat
ggaatgtccatggatttgcctctcccaccacccccttccgccaaccagatagggctgccg
tctgcgcaggtggctgctgctgaacggagaaagagagaagaacatcagcgttggtatgag
aaggagaaggcccgcctggaggaggagcgggagaggaagcggagagagcaggagaggaag
ttgggccagatgcgcactcagtccttaaaccctgctccgttttctcccctgactgcacag
cagatgaagcccgaaaagccttccacactccagcggccacaggaaacagtcattcgggag
ctgcagcctcagcagcagccccgcacgatcgagcgcagagacttgcagtacattacagtc
agcaaagaggagctttcctcgggggacagtctgtcccccgacccgtggaagcgggacgcc
aaggagaagctggagaagcagcagcagatgcacatcgtggacatgctgagcaaggagatc
caggagctccagagcaaaccggaccgcagcgccgaggagagcgaccggctgcgcaagctc
atgctggagtggcagttccagaagagactccaggagtcgaagcagaaggacgaagatgac
gaggaggaggaggacgatgatgtggacaccatgctgatcatgcagcgcctggaggctgaa
cgaagagcgagggacgaggagcggaggcggcagcagcagttagaagagatgcgcaagcgg
gaagcggaagaccgagcgaggcaagaggaagagcgccggcggcaggaggaggagcgaaca
aaacgagacgctgaagaaaaggttatggtcctttaa

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (3)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (44)   
   RefSeq(nuc) (4)   
   GenBank (20)   
   EMBL (20)   
3D Structure (4)   
   PDB (4)   
Protein domain (5)   
   Pfam (5)   
All databases (79)   

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