KEGG   Homo sapiens (human): 4301Help
Entry
4301              CDS       T01001                                 

Gene name
MLLT4, AF6
Definition
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
Orthology
K05702  
afadin
Organism
hsa  Homo sapiens (human)
Pathway
Ras signaling pathway
Rap1 signaling pathway
cAMP signaling pathway
Adherens junction
Tight junction
Leukocyte transendothelial migration
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    4301 (MLLT4)
   04015 Rap1 signaling pathway
    4301 (MLLT4)
   04024 cAMP signaling pathway
    4301 (MLLT4)
 Cellular Processes
  Cellular commiunity
   04520 Adherens junction
    4301 (MLLT4)
   04530 Tight junction
    4301 (MLLT4)
 Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    4301 (MLLT4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
6q27
AA seq 1651 aa AA seqDB search
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA
SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS
DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV
MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE
GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR
LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET
TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI
HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI
LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT
HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA
HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA
ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD
CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE
NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC
QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL
SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR
TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS
PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV
STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT
DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE
HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD
GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK
LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV
SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL
MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKR
EAEDRARQEEERRRQEEERTKRDAEEKVMVL
NT seq 4956 nt NT seq  +upstreamnt  +downstreamnt
atgtcggcgggcggccgtgacgaggagcggcggaagctggccgacatcatccaccactgg
aacgccaaccggctggacctgttcgagatcagccagccgaccgaggatttggagttccat
ggagtgatgagattttattttcaagataaagctgctggaaactttgcaacaaaatgtatt
cgggtctctagtactgccaccactcaagatgtaatcgaaacgctcgcggagaaatttcga
cctgatatgcgaatgctgtcctctcccaagtattcactctatgaagtgcatgtcagcgga
gaaagaagattggatatagatgagaaacctctagttgtacaactgaattggaacaaagat
gatcgggaaggcagatttgttcttaagaatgagaatgacgccattcctcctaagaaggct
caaagtaatggacctgaaaagcaggaaaaagaaggggttatccagaacttcaagagaact
ctctcaaagaaagaaaagaaggaaaaaaagaagagagaaaaagaggcattgcgacaggca
tctgataaagatgatagacctttccaaggggaggatgttgaaaattctcgactggctgct
gaggtttacaaagacatgccggaaaccagctttactcgaaccatttctaatcctgaggtg
gttatgaaacgacggaggcagcaaaaattggaaaagagaatgcaggaatttcggagctca
gatgggcggcctgattcaggtggaacattgagaatttatgcagatagtttaaaaccaaat
attccctacaagacaatcctgctgtctactacagatcctgcagactttgctgtggctgaa
gctttagagaagtatggtctggaaaaagaaaaccctaaggattactgcatcgcccgggtt
atgcttcctcctggagcccagcattctgatgaaaagggtgctaaagaaattattcttgat
gatgatgagtgtcctttacaaatcttcagggaatggccaagtgacaaagggattttagtc
tttcagttgaagaggaggccaccagaccacatcccaaagaaaaccaagaaacacttggaa
ggcaagacacccaagggaaaggagagagctgacgggtctggctatggctccacccttcct
ccggagaagctgccctatttagtagagttaagcccagggagaaggaatcactttgcctac
tacaactatcacacttacgaagatggttctgactctagagataagccaaagctttaccgc
cttcagttaagtgttactgaagttgggacagaaaagttggatgacaactctatccagttg
tttggcccaggaattcagccccatcactgtgaccttaccaacatggatggagtggtcact
gtgacgcccagaagtatggacgcagaaacctacgtggaaggccagcgcatctcagaaacc
accatgctgcagagtggcatgaaagtgcagtttggggcgtcccatgtatttaagtttgtg
gaccccagtcaggatcatgctcttgcaaaaagatctgtggatggaggcctgatggttaag
ggcccaagacataaacctggaattgttcaggagacaacttttgatttgggaggagatatt
catagtgggacagcattaccgacaagcaagagcaccactaggctggacagcgacagagtg
tcgtctgcctctagcacagccgagcggggaatggtgaagccgatgatcagagtagaacag
cagccagattatcgcaggcaagaaagcagaacacaggatgcttctgggcctgagctgata
ctacctgcaagcattgaattcagggaaagttctgaagattcatttttgtctgccattata
aattatactaatagctctacagtccactttaagttgtcccctacatatgtattatatatg
gcatgccggtatgtattgtccaaccagtacagacctgacatcagccctacagagcgcaca
cataaagtcattgcagtcgtcaacaagatggtgagcatgatggagggtgtcatccagaaa
cagaagaatattgcaggggcacttgccttctggatggcaaatgcatctgaacttctcaac
ttcattaagcaagaccgagaccttagtcggatcacactggatgctcaagatgttttagca
catttggttcaaatggcatttaaatacttggttcactgtcttcaatcagaacttaataat
tacatgccagcctttctagatgaccctgaagagaacagtctgcaacgaccaaaaatagat
gatgtgctgcacacgctcacaggagccatgtccttgctacgacgctgcagagtcaatgcc
gccctgaccatccagctcttctctcagctcttccacttcatcaatatgtggctgttcaat
agattggtgaccgacccagattcggggctgtgctcccattactggggtgcgattatccgt
cagcagttgggccatattgaagcctgggctgagaagcaggggctggaactggctgcggac
tgtcatctgagcaggatcgtgcaggcaacgactttgcttaccatggataagtatgcacct
gatgacattccaaatataaacagcacctgctttaagttaaattcattacaacttcaagcc
ttattacagaactatcactgtgcacctgatgagccttttatcccaacggatcttatagaa
aatgtagtgactgtggctgaaaacactgccgatgagctggcccgcagtgatggaagggaa
gtgcagttggaggaggatcctgatctgcagctgccgtttcttttgccagaagatggttat
tcttgtgatgttgtcagaaacattccaaatggtttacaagaatttttagaccctctgtgc
cagagaggattttgcaggttaattcctcacacacgttcaccaggtacttggacaatatat
tttgaaggtgcagattatgaaagtcaccttctgcgtgagaacacagagctggctcagcct
ctgaggaaagaacctgaaataatcactgtgaccctaaaaaagcagaatggaatgggcctt
agcattgttgcagcaaagggtgctggtcaagataaactaggaatctatgtgaagtcggtt
gtgaaaggaggtgctgcagatgtggatggacgtctagctgcaggtgatcagctcctcagt
gtggatggacgaagtctggttggactctctcaggaaagggcggcagaactcatgacaaga
acaagctctgtggtgacactggaagtagcaaagcagggtgccatctaccacggtctggcc
acccttctcaatcagccatcccccatgatgcagagaatttcagatcgtcgtggctcaggt
aaaccccgaccaaagagtgaaggctttgagctctataataattcaactcaaaatgggtct
cctgagagtcctcagctgccttgggcagaatatagtgaaccaaagaaattgcctggtgat
gacagactgatgaaaaatagagctgatcaccgttccagccccaacgtagcaaatcagcct
cctagtcctggagggaaaagtgcatatgcctctggaacaacagcgaagataacatctgtc
tctactggaaacctctgcactgaggagcagacgcctccgcctagacctgaagcctacccc
atccccactcagacgtacaccagagagtattttaccttcccagcttccaaatcccaggat
cggatggctcctcctcagaaccagtggccaaattatgaggaaaagccacatatgcacaca
gatagtaatcattccagtattgcaattcagcgtgttacacgttcccaagaagaacttcga
gaagataaagcttaccaacttgagcggcatcgaatagaggcagctatggaccgaaagtct
gatagtgatatgtggataaatcagagctcctcactggactccagtacctctagccaggag
catctgaaccattcctctaagtcggtcacccctgcttccacactgaccaaaagtggccct
ggccgttggaaaacaccagcagccataccggccacccctgtggccgtctcccagccaatc
cgaacagacctgcctccgccacccccgccacctccagtccactatgccggtgatttcgat
ggaatgtccatggatttgcctctcccaccacccccttccgccaaccagatagggctgccg
tctgcgcaggtggctgctgctgaacggagaaagagagaagaacatcagcgttggtatgag
aaggagaaggcccgcctggaggaggagcgggagaggaagcggagagagcaggagaggaag
ttgggccagatgcgcactcagtccttaaaccctgctccgttttctcccctgactgcacag
cagatgaagcccgaaaagccttccacactccagcggccacaggaaacagtcattcgggag
ctgcagcctcagcagcagccccgcacgatcgagcgcagagacttgcagtacattacagtc
agcaaagaggagctttcctcgggggacagtctgtcccccgacccgtggaagcgggacgcc
aaggagaagctggagaagcagcagcagatgcacatcgtggacatgctgagcaaggagatc
caggagctccagagcaaaccggaccgcagcgccgaggagagcgaccggctgcgcaagctc
atgctggagtggcagttccagaagagactccaggagtcgaagcagaaggacgaagatgac
gaggaggaggaggacgatgatgtggacaccatgctgatcatgcagcgcctggaggctgaa
cgaagagcgagggacgaggagcggaggcggcagcagcagttagaagagatgcgcaagcgg
gaagcggaagaccgagcgaggcaagaggaagagcgccggcggcaggaggaggagcgaaca
aaacgagacgctgaagaaaaggttatggtcctttaa

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