| Entry |
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| Gene name |
MMP14, 1, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1
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| Definition |
matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80)
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| Orthology |
| matrix metalloproteinase-14 (membrane-inserted) [EC: 3.4.24.80] |
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| Organism |
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| Pathway |
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| Drug target |
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| Class |
Environmental Information Processing; Signal transduction; TNF signaling pathway
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH: hsa04912]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Structure |
PDB: |
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| Position |
14q11-q12
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| AA seq |
582 aa  
MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS
LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ
HNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIF
FAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHE
LGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTT
SRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQF
WRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALF
WMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKG
NKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAA
AVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV |
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| NT seq |
1749 nt  +upstreamnt +downstreamnt
atgtctcccgccccaagacccccccgttgtctcctgctccccctgctcacgctcggcacc
gcgctcgcctccctcggctcggcccaaagcagcagcttcagccccgaagcctggctacag
caatatggctacctgcctcccggggacctacgtacccacacacagcgctcaccccagtca
ctctcagcggccatcgctgccatgcagaagttttacggcttgcaagtaacaggcaaagct
gatgcagacaccatgaaggccatgaggcgcccccgatgtggtgttccagacaagtttggg
gctgagatcaaggccaatgttcgaaggaagcgctacgccatccagggtctcaaatggcaa
cataatgaaatcactttctgcatccagaattacacccccaaggtgggcgagtatgccaca
tacgaggccattcgcaaggcgttccgcgtgtgggagagtgccacaccactgcgcttccgc
gaggtgccctatgcctacatccgtgagggccatgagaagcaggccgacatcatgatcttc
tttgccgagggcttccatggcgacagcacgcccttcgatggtgagggcggcttcctggcc
catgcctacttcccaggccccaacattggaggagacacccactttgactctgccgagcct
tggactgtcaggaatgaggatctgaatggaaatgacatcttcctggtggctgtgcacgag
ctgggccatgccctggggctcgagcattccagtgacccctcggccatcatggcacccttt
taccagtggatggacacggagaattttgtgctgcccgatgatgaccgccggggcatccag
caactttatgggggtgagtcagggttccccaccaagatgccccctcaacccaggactacc
tcccggccttctgttcctgataaacccaaaaaccccacctatgggcccaacatctgtgac
gggaactttgacaccgtggccatgctccgaggggagatgtttgtcttcaaggagcgctgg
ttctggcgggtgaggaataaccaagtgatggatggatacccaatgcccattggccagttc
tggcggggcctgcctgcgtccatcaacactgcctacgagaggaaggatggcaaattcgtc
ttcttcaaaggagacaagcattgggtgtttgatgaggcgtccctggaacctggctacccc
aagcacattaaggagctgggccgagggctgcctaccgacaagattgatgctgctctcttc
tggatgcccaatggaaagacctacttcttccgtggaaacaagtactaccgtttcaacgaa
gagctcagggcagtggatagcgagtaccccaagaacatcaaagtctgggaagggatccct
gagtctcccagagggtcattcatgggcagcgatgaagtcttcacttacttctacaagggg
aacaaatactggaaattcaacaaccagaagctgaaggtagaaccgggctaccccaagtca
gccctgagggactggatgggctgcccatcgggaggccggccggatgaggggactgaggag
gagacggaggtgatcatcattgaggtggacgaggagggcggcggggcggtgagcgcggct
gccgtggtgctgcccgtgctgctgctgctcctggtgctggcggtgggccttgcagtcttc
ttcttcagacgccatgggacccccaggcgactgctctactgccagcgttccctgctggac
aaggtctga |
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