KEGG   Homo sapiens (human): 4537Help
Entry
4537              CDS       T01001                                 

Gene name
ND3, MTND3, MT-ND3
Definition
(RefSeq) NADH dehydrogenase, subunit 3 (complex I)
  KO
K03880  
NADH-ubiquinone oxidoreductase chain 3 [EC:1.6.5.3]
Organism
hsa  Homo sapiens (human)
Pathway
Oxidative phosphorylation
Metabolic pathways
Retrograde endocannabinoid signaling
Parkinson's disease
Module
NADH:ubiquinone oxidoreductase, mitochondria
Disease
H00473  
Mitochondrial respiratory chain deficiencies (MRCD)
H01355  
Kearns-Sayre Syndrome
H01365  
Leber hereditary optic neuropathy and dystonia (LDYT)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Energy metabolism
   00190 Oxidative phosphorylation
    4537 (ND3)
 Organismal Systems
  Nervous system
   04723 Retrograde endocannabinoid signaling
    4537 (ND3)
 Human Diseases
  Neurodegenerative diseases
   05012 Parkinson's disease
    4537 (ND3)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.5  With a quinone or similar compound as acceptor
    1.6.5.3  NADH:ubiquinone reductase (H+-translocating)
     4537 (ND3)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    4537 (ND3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Pharos: 
P03897(Tclin)
UniProt: 
Position
MT
AA seq 115 aa AA seqDB search
MNFALILMINTLLALLLMIITFWLPQLNGYMEKSTPYECGFDPMSPARVPFSMKFFLVAI
TFLLFDLEIALLLPLPWALQTTNLPLMVMSSLLLIIILALSLAYEWLQKGLDWTE
NT seq 346 nt NT seq  +upstreamnt  +downstreamnt
ataaacttcgccttaattttaataatcaacaccctcctagccttactactaataattatt
acattttgactaccacaactcaacggctacatagaaaaatccaccccttacgagtgcggc
ttcgaccctatatcccccgcccgcgtccctttctccataaaattcttcttagtagctatt
accttcttattatttgatctagaaattgccctccttttacccctaccatgagccctacaa
acaactaacctgccactaatagttatgtcatccctcttattaatcatcatcctagcccta
agtctggcctatgagtgactacaaaaaggattagactgaaccgaat

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