KEGG T01001: 4543

Homo sapiens (human): 4543

Entry

4543 CDS T01001

Gene name

MTNR1A, MEL-1A-R, MT1

Definition

melatonin receptor 1A

Orthology

K04285

melatonin receptor type 1A

Organism

hsa Homo sapiens (human)

Pathway

hsa04080	Neuroactive ligand-receptor interaction
hsa04713	Circadian entrainment

Drug target

Melatonin:

D08170

Ramelteon:

D02689

Other:

D01438 D09388

Class

Environmental Information Processing; Signaling molecules and interaction; Neuroactive ligand-receptor interaction [PATH:hsa04080]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:hsa04713]

SSDB

Motif

Pfam:

7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx PHO4

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

4q35.1

AA seq 350 aa
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV

NT seq 1053 nt +upstreamnt +downstreamnt
atgcagggcaacggcagcgcgctgcccaacgcctcccagcccgtgctccgcggggacggc
gcgcggccctcgtggctggcgtccgccctggcctgcgtcctcatcttcaccatcgtggtg
gacatcctgggcaacctcctggtcatcctgtcggtgtatcggaacaagaagctcaggaac
gcaggaaacatctttgtggtgagcttagcggtggcagacctggtggtggccatttatccg
tacccgttggtgctgatgtcgatatttaacaacgggtggaacctgggctatctgcactgc
caagtcagtgggttcctgatgggcctgagcgtcatcggctccatattcaacatcaccggc
atcgccatcaaccgctactgctacatctgccacagtctcaagtacgacaaactgtacagc
agcaagaactccctctgctacgtgctcctcatatggctcctgacgctggcggccgtcctg
cccaacctccgtgcagggactctccagtacgacccgaggatctactcgtgcaccttcgcc
cagtccgtcagctccgcctacaccatcgccgtggtggttttccacttcctcgtccccatg
atcatagtcatcttctgttacctgagaatatggatcctggttctccaggtcagacagagg
gtgaaacctgaccgcaaacccaaactgaaaccacaggacttcaggaattttgtcaccatg
tttgtggtttttgtcctttttgccatttgctgggctcctctgaacttcattggcctggcc
gtggcctctgaccccgccagcatggtgcctaggatcccagagtggctgtttgtggccagt
tactacatggcgtatttcaacagctgcctcaatgccattatatacgggctactgaaccaa
aatttcaggaaggaatacaggagaattatagtctcgctctgtacagccagggtgttcttt
gtggacagctctaacgacgtggccgatagggttaaatggaaaccgtctccactgatgacc
aacaataatgtagtaaaggtggactccgtttaa

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (4)   
   KEGG DRUG (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (10)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
Protein domain (4)   
   Pfam (4)   
All databases (55)   

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