| Entry |
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| Gene name |
NAGLU, MPS-IIIB, MPS3B, NAG, UFHSD
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| Definition |
N-acetylglucosaminidase, alpha (EC:3.2.1.50)
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| Orthology |
| alpha-N-acetylglucosaminidase [EC: 3.2.1.50] |
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| Organism |
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| Pathway |
| Glycosaminoglycan degradation | | Metabolic pathways | | Lysosome |
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| Module |
| Heparan sulfate degradation |
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| Disease |
| Mucopolysaccharidosis type III (MPS3) |
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| Class |
Metabolism; Glycan biosynthesis and metabolism; Glycosaminoglycan degradation [PATH: hsa00531]
Cellular Processes; Transport and catabolism; Lysosome [PATH: hsa04142]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Position |
17q21
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| AA seq |
743 aa  
MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKP
GLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGE
LTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYL
ALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTP
VLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELI
KEFGTDHIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQF
WGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGAL
EAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAA
RRYGVSHPDAGAAWRLLLRSVYNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAW
RLLLTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKELASLLRAGGVLAY
ELLPALDEVLASDSRFLLGSWLEQARAAAVSEAEADFYEQNSRYQLTLWGPEGNILDYAN
KQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPR
GDTVDLAKKIFLKYYPRWVAGSW |
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| NT seq |
2232 nt  +upstreamnt +downstreamnt
atggaggcggtggcggtggccgcggcggtgggggtccttctcctggccggggccgggggc
gcggcaggcgacgaggcccgggaggcggcggccgtgcgggcgctcgtggcccggctgctg
gggccaggccccgcggccgacttctccgtgtcggtggagcgcgctctggctgccaagccg
ggcttggacacctacagcctgggcggcggcggcgcggcgcgcgtgcgggtgcgcggctcc
acgggcgtggcggccgccgcggggctgcaccgctacctgcgcgacttctgtggctgccac
gtggcctggtccggctctcagctgcgcctgccgcggccactgccagccgtgccgggggag
ctgaccgaggccacgcccaacaggtaccgctattaccagaatgtgtgcacgcaaagctac
tctttcgtgtggtgggactgggcccgctgggagcgagagatagactggatggcgctgaat
ggcatcaacctggcactggcctggagcggccaggaggccatctggcagcgggtgtacctg
gccttgggcctgacccaggcagagatcaatgagttctttactggtcctgccttcctggcc
tgggggcgaatgggcaacctgcacacctgggatggccccctgcccccctcctggcacatc
aagcagctttacctgcagcaccgggtcctggaccagatgcgctccttcggcatgacccca
gtgctgcctgcattcgcggggcatgttcccgaggctgtcaccagggtgttccctcaggtc
aatgtcacgaagatgggcagttggggccactttaactgttcctactcctgctccttcctt
ctggctccggaagaccccatattccccatcatcgggagcctcttcctgcgagagctgatc
aaagagtttggcacagaccacatctatggggccgacactttcaatgagatgcagccacct
tcctcagagccctcctaccttgccgcagccaccactgccgtctatgaggccatgactgca
gtggatactgaggctgtgtggctgctccaaggctggctcttccagcaccagccgcagttc
tgggggcccgcccagatcagggctgtgctgggagctgtgccccgtggccgcctcctggtt
ctggacctgtttgctgagagccagcctgtgtatacccgcactgcctccttccagggccag
cccttcatctggtgcatgctgcacaactttgggggaaaccatggtctttttggagcccta
gaggctgtgaacggaggcccagaagctgcccgcctcttccccaactccaccatggtaggc
acgggcatggcccccgagggcatcagccagaacgaagtggtctattccctcatggctgag
ctgggctggcgaaaggacccagtgccagatttggcagcctgggtgaccagctttgccgcc
cggcggtatggggtctcccacccggacgcaggggcagcgtggaggctactgctccggagt
gtgtacaactgctccggggaggcctgcaggggccacaatcgtagcccgctggtcaggcgg
ccgtccctacagatgaataccagcatctggtacaaccgatctgatgtgtttgaggcctgg
cggctgctgctcacatctgctccctccctggccaccagccccgccttccgctacgacctg
ctggacctcactcggcaggcagtgcaggagctggtcagcttgtactatgaggaggcaaga
agcgcctacctgagcaaggagctggcctccctgttgagggctggaggcgtcctggcctat
gagctgctgccggcactggacgaggtgctggctagtgacagccgcttcttgctgggcagc
tggctagagcaggcccgagcagcggcagtcagtgaggccgaggccgatttctacgagcag
aacagccgctaccagctgaccttgtgggggccagaaggcaacatcctggactatgccaac
aagcagctggcggggttggtggccaactactacacccctcgctggcggcttttcctggag
gcgctggttgacagtgtggcccagggcatccctttccaacagcaccagtttgacaaaaat
gtcttccaactggagcaggccttcgttctcagcaagcagaggtaccccagccagccgcga
ggagacactgtggacctggccaagaagatcttcctcaaatattacccccgctgggtggcc
ggctcttggtga |
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