KEGG T01001: 4688

Homo sapiens (human): 4688

Entry

4688 CDS T01001

Gene name

NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX

Definition

neutrophil cytosolic factor 2

Orthology

K08010

neutrophil cytosolic factor 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04145	Phagosome
hsa04380	Osteoclast differentiation
hsa04670	Leukocyte transendothelial migration
hsa05140	Leishmaniasis

Disease

H00098

Chronic granulomatous disease

Class

Cellular Processes; Transport and catabolism; Phagosome [PATH:hsa04145]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:hsa04670]
Organismal Systems; Development; Osteoclast differentiation [PATH:hsa04380]
Human Diseases; Infectious diseases; Leishmaniasis [PATH:hsa05140]

SSDB

Motif

Pfam:

SH3_1 SH3_9 SH3_2 TPR_2 TPR_1 TPR_11 TPR_12 PB1 TPR_8 TPR_16 TPR_17 TPR_9 TPR_6

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1WM5 2DMO 1OEY 1K4U 1HH8 1E96

Position

1q25

AA seq 526 aa
MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV

NT seq 1581 nt +upstreamnt +downstreamnt
atgtccctggtggaggccatcagcctctggaatgaaggggtgctggcagcggacaagaag
gactggaagggagccctggatgccttcagtgccgtccaggacccccactcccggatttgc
ttcaacattggctgcatgtacactatcctgaagaacatgactgaagcagagaaggccttt
accagaagcattaaccgagacaagcacttggcagtggcttacttccaacgagggatgctc
tactaccagacagagaaatatgatttggctatcaaagaccttaaagaagccttgattcag
cttcgagggaaccagctgatagactataagatcctggggctccagttcaagctgtttgcc
tgtgaggtgttatataacattgctttcatgtatgccaagaaggaggaatggaaaaaagct
gaagaacagttagcattggccacgagcatgaagtctgagcccagacattccaaaatcgac
aaggcgatggagtgtgtctggaagcagaagctatatgagccagtggtgatccctgtgggc
aagctgtttcgaccaaatgagagacaagtggctcagctggccaagaaggattacctaggc
aaggcgacggtcgtggcatctgtggtggatcaagacagtttctctgggtttgcccctctg
caaccacaggcagctgagcctccacccagaccgaaaaccccagagatcttcagggctctg
gaaggggaggctcaccgtgtgctatttgggtttgtgcctgagacaaaagaagagctccag
gtcatgccagggaacattgtctttgtcttgaagaagggcaatgataactgggccacggtc
atgttcaacgggcagaaggggcttgttccctgcaactaccttgaaccagttgagctgcgg
atccaccctcagcagcagccccaggaggaaagctctccgcagtccgacatcccagctcct
cctagttccaaagcccctggaagaccccagctgtcaccaggccagaaacaaaaagaagag
cctaaggaagtgaagctcagtgttcccatgccctacacactcaaggtgcactacaagtac
acggtagtcatgaagactcagcccgggctcccctacagccaggtccgggacatggtgtct
aagaaactggagctccggctggaacacactaagctgagctatcggcctcgggacagcaat
gagctggtgcccctttcagaagacagcatgaaggatgcctggggccaggtgaaaaactac
tgcctgactctgtggtgtgagaacacagtgggtgaccaaggctttccagatgaacccaag
gaaagtgaaaaagctgatgctaataaccagacaacagaacctcagcttaagaaaggcagc
caagtggaggcactcttcagttatgaggctacccaaccagaggacctggagtttcaggaa
ggggatataatcctggtgttatcaaaggtgaatgaagaatggctggaaggggagtgcaaa
gggaaggtgggcattttccccaaagtttttgttgaagactgcgcaactacagatttggaa
agcactcggagagaagtctag

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (11)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (40)   
   RefSeq(nuc) (4)   
   GenBank (18)   
   EMBL (18)   
3D Structure (6)   
   PDB (6)   
Protein domain (13)   
   Pfam (13)   
All databases (92)   

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