KEGG   Homo sapiens (human): 4719Help
Entry
4719              CDS       T01001                                 
Gene name
NDUFS1, CI-75Kd, CI-75k, PRO1304
Definition
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)
Orthology
K03934  
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
Organism
hsa  Homo sapiens (human)
Pathway
Oxidative phosphorylation
Metabolic pathways
Alzheimer's disease
Parkinson's disease
Huntington's disease
Module
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Disease
H00473  
Mitochondrial respiratory chain deficiencies (MRCD)
Class
Metabolism; Energy metabolism; Oxidative phosphorylation [PATH:hsa00190]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:hsa05010]
Human Diseases; Neurodegenerative diseases; Parkinson's disease [PATH:hsa05012]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:hsa05016]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
UniProt: 
Position
2q33-q34
AA seq 691 aa AA seqDB search
MLRIPVRKALVGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQVVAACAMPV
MKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLEG
KRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMS
ELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPR
MHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGK
DVAAIAGGLVDAEALVALKDLLNRVDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEE
ADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYTYDHLGDSPKILQDIA
SGSHPFSQVLKEAKKPMVVLGSSALQRNDGAAILAAVSSIAQKIRMTSGVTGDWKVMNIL
HRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVG
APIADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPY
DTLDQVRNRLEEVSPNLVRYDDIEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYM
TDSISRASQTMAKCVKAVTEGAQAVEEPSIC
NT seq 2076 nt NT seq  +upstreamnt  +downstreamnt
atgttaaggatacctgtaagaaaggccttagtaggcctttctaagtctcctaaaggatgt
gttcgaacaactgccacagcagcaagcaacttgattgaagtatttgttgatggtcagtct
gtcatggtggaaccgggaacgaccgtcctccaagttgtagctgcttgtgccatgccagta
atgaagggttggaatatcctaacaaactcagaaaaatccaaaaaagccagggaaggtgtg
atggagttcttattagcaaatcacccattggactgtcctatttgtgaccagggaggtgaa
tgtgatctgcaggaccagtccatgatgtttggaaatgataggagccgatttttagagggg
aagcgtgctgtggaagacaagaacattgggccattggtaaagaccatcatgacaagatgt
atacagtgtactcgctgcatcaggtttgcaagtgagattgcaggagtagatgatttggga
acaacaggcagaggaaatgatatgcaagttggcacatacattgaaaagatgttcatgtct
gaactgtctgggaatatcattgatatctgccctgtaggtgccctaacctctaagccctat
gcctttactgcccggccttgggaaacaagaaagacagaatccattgatgtaatggatgcg
gttggaagtaatattgtggttagcacaagaactggagaagtgatgaggattttgccacgt
atgcatgaggacatcaatgaagagtggatctctgataaaaccagatttgcctatgatggg
ctaaaacgtcaaagacttaccgagccaatggtcagaaatgaaaaagggcttttaacctat
acttcttgggaggatgcgctctctcgcgtagctggaatgttgcagagttttcaaggcaaa
gatgtggcagcaattgcaggtggcttggtggatgctgaagccctggtagctctcaaagat
ttgcttaatagagtggactctgacaccttatgcactgaagaggtcttccccactgcagga
gctggcacagatttgcgttccaattatcttcttaatactacaattgctggtgtggaagag
gcagatgttgttcttctggttggtacaaacccacgttttgaggcaccactgtttaatgct
agaattcgaaagagctggctgcataatgacttaaaagtggcccttataggcagtccagtg
gacctcacttacacatatgaccacctgggagactcccccaaaattcttcaagacattgct
tcgggaagccatccatttagccaggtcctaaaggaagctaaaaaaccaatggtggtttta
ggcagttctgcactccaaagaaatgatggagcagcaattcttgcagctgtttctagcatt
gcacaaaagattcggatgactagtggtgttactggtgattggaaagttatgaatatcctt
cataggattgcaagtcaagtagctgctttggaccttggctataagcctggggtggaagca
attcggaagaaccctcccaaggtgctgtttctcctgggagcagatggaggttgtatcaca
cgacaggatttgccaaaggattgtttcattatttatcaaggacatcatggtgatgttggg
gctcccatagctgatgttattctcccaggagctgcttacacagagaagtctgctacatat
gtcaacactgagggtagagctcagcagactaaggtagcagtgacacctcctggcttggca
agagaagactggaaaattataagagcactctctgagattgctggaatgactcttccatat
gatactctggatcaagtaaggaacagattggaagaagtctctcctaatcttgttcgatat
gatgatattgaaggggctaattacttccagcaagcaaatgagctctcaaagctagtgaac
cagcagcttcttgctgacccacttgttccacctcagctaactataaaagacttctacatg
acagattcaattagcagagcctcacagacaatggccaaatgtgtcaaagctgtcacagag
ggtgcccaggcagtagaggaaccatccatatgctga
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