KEGG   Homo sapiens (human): 4988Help
Entry
4988              CDS       T01001                                 

Gene name
OPRM1, LMOR, M-OR-1, MOP, MOR, MOR1, OPRM
Definition
(RefSeq) opioid receptor mu 1
  KO
K04215  
mu-type opioid receptor
Organism
hsa  Homo sapiens (human)
Pathway
Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
Disease
H01611  
Alcohol dependence
Drug target
Alfentanil (DG00792): 
Alvimopan: 
Buprenorphine (DG00820): 
Butorphanol (DG00821): 
Carfentanil (DG01339): 
Codeine (DG01076): 
Diamorphine (DG01003): 
Dihydrocodeine (DG00814): 
Diphenoxylate (DG00090): 
Diprenorphine (DG01273): 
Eluxadoline: 
Eptazocine (DG01340): 
Ethoheptazine citrate: 
Ethylmorphine (DG01074): 
Fentanyl (DG00791): 
Hydrocodone (DG01075): 
Hydromorphone (DG00811): 
Levallorphan (DG02409): 
Levomethadone (DG01002): 
Levorphanol (DG01341): 
Loperamide (DG00092): 
Loperamide oxide (DG00092): 
Meptazinol (DG00825): 
Methadone (DG00999): 
Methylnaltrexone bromide: 
Morphine (DG00810): 
Nalbuphine (DG00822): 
Naldemedine (DG01342): 
Naloxone (DG01155): 
Naltrexone (DG00997): 
Oxycodone (DG00813): 
Oxymorphone (DG01343): 
Pentazocine (DG00819): 
Pethidine (DG00816): 
Remifentanil (DG00795): 
Samidorphan (DG01538): 
Sufentanil (DG00793): 
Tapentadol (DG00826): 
Tilidine (DG00823): 
Tramadol (DG00824): 
Trefentanil hydrochloride: 
Trimebutine (DG00031): 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    4988 (OPRM1)
 Organismal Systems
  Endocrine system
   04915 Estrogen signaling pathway
    4988 (OPRM1)
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    4988 (OPRM1)
G protein-coupled receptors [BR:hsa04030]
 Class A. Rhodopsin family
  Neuropeptide
   Opioid
    4988 (OPRM1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
OMIM: 
HGNC: 
Ensembl: 
Vega: 
Pharos: 
P35372(Tclin)
UniProt: 
Position
6q25.2
AA seq 400 aa AA seqDB search
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
NT seq 1203 nt NT seq  +upstreamnt  +downstreamnt
atggacagcagcgctgcccccacgaacgccagcaattgcactgatgccttggcgtactca
agttgctccccagcacccagccccggttcctgggtcaacttgtcccacttagatggcaac
ctgtccgacccatgcggtccgaaccgcaccgacctgggcgggagagacagcctgtgccct
ccgaccggcagtccctccatgatcacggccatcacgatcatggccctctactccatcgtg
tgcgtggtggggctcttcggaaacttcctggtcatgtatgtgattgtcagatacaccaag
atgaagactgccaccaacatctacattttcaaccttgctctggcagatgccttagccacc
agtaccctgcccttccagagtgtgaattacctaatgggaacatggccatttggaaccatc
ctttgcaagatagtgatctccatagattactataacatgttcaccagcatattcaccctc
tgcaccatgagtgttgatcgatacattgcagtctgccaccctgtcaaggccttagatttc
cgtactccccgaaatgccaaaattatcaatgtctgcaactggatcctctcttcagccatt
ggtcttcctgtaatgttcatggctacaacaaaatacaggcaaggttccatagattgtaca
ctaacattctctcatccaacctggtactgggaaaacctgctgaagatctgtgttttcatc
ttcgccttcattatgccagtgctcatcattaccgtgtgctatggactgatgatcttgcgc
ctcaagagtgtccgcatgctctctggctccaaagaaaaggacaggaatcttcgaaggatc
accaggatggtgctggtggtggtggctgtgttcatcgtctgctggactcccattcacatt
tacgtcatcattaaagccttggttacaatcccagaaactacgttccagactgtttcttgg
cacttctgcattgctctaggttacacaaacagctgcctcaacccagtcctttatgcattt
ctggatgaaaacttcaaacgatgcttcagagagttctgtatcccaacctcttccaacatt
gagcaacaaaactccactcgaattcgtcagaacactagagaccacccctccacggccaat
acagtggatagaactaatcatcagctagaaaatctggaagcagaaactgctccgttgccc
taa

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