KEGG   Homo sapiens (human): 4988Help
Entry
4988              CDS       T01001                                 

Gene name
OPRM1, LMOR, M-OR-1, MOP, MOR, MOR1, OPRM
Definition
(RefSeq) opioid receptor mu 1
  KO
K04215  
mu-type opioid receptor
Organism
hsa  Homo sapiens (human)
Pathway
Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
Disease
H01611  
Alcohol dependence
Drug target
Trimebutine [DG:DG00031]: 
Methylnaltrexone bromide: 
Alvimopan: 
Naloxegol [DG:DG00078]: 
Diphenoxylate [DG:DG00090]: 
Loperamide [DG:DG00092]: 
Difenoxin: 
Loperamide oxide [DG:DG00092]: 
Fentanyl [DG:DG00791]: 
Alfentanil [DG:DG00792]: 
Sufentanil [DG:DG00793]: 
Remifentanil [DG:DG00795]: 
Morphine [DG:DG00810]: 
Hydromorphone [DG:DG00811]: 
Oxycodone [DG:DG00813]: 
Dihydrocodeine [DG:DG00814]: 
Pethidine [DG:DG00816]: 
Dextropropoxyphene [DG:DG00818]: 
Pentazocine [DG:DG00819]: 
Buprenorphine [DG:DG00820]: 
Butorphanol [DG:DG00821]: 
Nalbuphine [DG:DG00822]: 
Tilidine [DG:DG00823]: 
Tramadol [DG:DG00824]: 
Dezocine: 
Meptazinol [DG:DG00825]: 
Tapentadol [DG:DG00826]: 
Naltrexone [DG:DG00997]: 
Nalmefene [DG:DG00998]: 
Methadone [DG:DG00999]: 
Levacetylmethadol [DG:DG01000]: 
Levomethadone [DG:DG01002]: 
Diamorphine [DG:DG01003]: 
Ethylmorphine [DG:DG01074]: 
Hydrocodone [DG:DG01075]: 
Codeine [DG:DG01076]: 
Acetyldihydrocodeine: 
Nalorphine [DG:DG01151]: 
Naloxone [DG:DG01155]: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    4988 (OPRM1)
 Organismal Systems
  Endocrine system
   04915 Estrogen signaling pathway
    4988 (OPRM1)
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    4988 (OPRM1)
G protein-coupled receptors [BR:hsa04030]
 Class A. Rhodopsin family
  Neuropeptide
   Opioid
    4988 (OPRM1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
6q24-q25
AA seq 400 aa AA seqDB search
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
NT seq 1203 nt NT seq  +upstreamnt  +downstreamnt
atggacagcagcgctgcccccacgaacgccagcaattgcactgatgccttggcgtactca
agttgctccccagcacccagccccggttcctgggtcaacttgtcccacttagatggcaac
ctgtccgacccatgcggtccgaaccgcaccgacctgggcgggagagacagcctgtgccct
ccgaccggcagtccctccatgatcacggccatcacgatcatggccctctactccatcgtg
tgcgtggtggggctcttcggaaacttcctggtcatgtatgtgattgtcagatacaccaag
atgaagactgccaccaacatctacattttcaaccttgctctggcagatgccttagccacc
agtaccctgcccttccagagtgtgaattacctaatgggaacatggccatttggaaccatc
ctttgcaagatagtgatctccatagattactataacatgttcaccagcatattcaccctc
tgcaccatgagtgttgatcgatacattgcagtctgccaccctgtcaaggccttagatttc
cgtactccccgaaatgccaaaattatcaatgtctgcaactggatcctctcttcagccatt
ggtcttcctgtaatgttcatggctacaacaaaatacaggcaaggttccatagattgtaca
ctaacattctctcatccaacctggtactgggaaaacctgctgaagatctgtgttttcatc
ttcgccttcattatgccagtgctcatcattaccgtgtgctatggactgatgatcttgcgc
ctcaagagtgtccgcatgctctctggctccaaagaaaaggacaggaatcttcgaaggatc
accaggatggtgctggtggtggtggctgtgttcatcgtctgctggactcccattcacatt
tacgtcatcattaaagccttggttacaatcccagaaactacgttccagactgtttcttgg
cacttctgcattgctctaggttacacaaacagctgcctcaacccagtcctttatgcattt
ctggatgaaaacttcaaacgatgcttcagagagttctgtatcccaacctcttccaacatt
gagcaacaaaactccactcgaattcgtcagaacactagagaccacccctccacggccaat
acagtggatagaactaatcatcagctagaaaatctggaagcagaaactgctccgttgccc
taa

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