KEGG   Homo sapiens (human): 51176Help
Entry
51176             CDS       T01001                                 

Gene name
LEF1, LEF-1, TCF10, TCF1ALPHA, TCF7L3
Definition
(RefSeq) lymphoid enhancer binding factor 1
  KO
K04492  
lymphoid enhancer-binding factor 1
Organism
hsa  Homo sapiens (human)
Pathway
Wnt signaling pathway
Hippo signaling pathway
Adherens junction
Melanogenesis
Pathways in cancer
Colorectal cancer
Endometrial cancer
Prostate cancer
Thyroid cancer
Basal cell carcinoma
Acute myeloid leukemia
Breast cancer
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Module
Wnt signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    51176 (LEF1)
   04390 Hippo signaling pathway
    51176 (LEF1)
 Cellular Processes
  Cellular community
   04520 Adherens junction
    51176 (LEF1)
 Organismal Systems
  Endocrine system
   04916 Melanogenesis
    51176 (LEF1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    51176 (LEF1)
   05210 Colorectal cancer
    51176 (LEF1)
   05216 Thyroid cancer
    51176 (LEF1)
   05221 Acute myeloid leukemia
    51176 (LEF1)
   05217 Basal cell carcinoma
    51176 (LEF1)
   05215 Prostate cancer
    51176 (LEF1)
   05213 Endometrial cancer
    51176 (LEF1)
   05224 Breast cancer
    51176 (LEF1)
  Cardiovascular diseases
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    51176 (LEF1)
Transcription factors [BR:hsa03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    51176 (LEF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
4q25
AA seq 399 aa AA seqDB search
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS
RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI
NT seq 1200 nt NT seq  +upstreamnt  +downstreamnt
atgccccaactctccggaggaggtggcggcggcgggggggacccggaactctgcgccacg
gacgagatgatccccttcaaggacgagggcgatcctcagaaggaaaagatcttcgccgag
atcagtcatcccgaagaggaaggcgatttagctgacatcaagtcttccttggtgaacgag
tctgaaatcatcccggccagcaacggacacgaggtggccagacaagcacaaacctctcag
gagccctaccacgacaaggccagagaacaccccgatgacggaaagcatccagatggaggc
ctctacaacaagggaccctcctactcgagttattccgggtacataatgatgccaaatatg
aataacgacccatacatgtcaaatggatctctttctccacccatcccgagaacatcaaat
aaagtgcccgtggtgcagccatcccatgcggtccatcctctcacccccctcatcacttac
agtgacgagcacttttctccaggatcacacccgtcacacatcccatcagatgtcaactcc
aaacaaggcatgtccagacatcctccagctcctgatatccctactttttatcccttgtct
ccgggtggtgttggacagatcaccccacctcttggctggcaaggtcagcctgtatatccc
atcacgggtggattcaggcaaccctacccatcctcactgtcagtcgacacttccatgtcc
aggttttcccatcatatgattcccggtcctcctggtccccacacaactggcatccctcat
ccagctattgtaacacctcaggtcaaacaggaacatccccacactgacagtgacctaatg
cacgtgaagcctcagcatgaacagagaaaggagcaggagccaaaaagacctcacattaag
aagcctctgaatgcttttatgttatacatgaaagaaatgagagcgaatgtcgttgctgag
tgtactctaaaagaaagtgcagctatcaaccagattcttggcagaaggtggcatgccctc
tcccgtgaagagcaggctaaatattatgaattagcacggaaagaaagacagctacatatg
cagctttatccaggctggtctgcaagagacaattatggtaagaaaaagaagaggaagaga
gagaaactacaggaatctgcatcaggtacaggtccaagaatgacagctgcctacatctga

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