KEGG T01001: 51284

Homo sapiens (human): 51284

Entry

51284 CDS T01001

Gene name

TLR7, TLR7-like

Definition

toll-like receptor 7

Orthology

K05404

toll-like receptor 7

Organism

hsa Homo sapiens (human)

Pathway

hsa04620	Toll-like receptor signaling pathway
hsa05162	Measles
hsa05164	Influenza A

Drug target

Imiquimod:

D02500

Other:

D04619 D04787

Class

Organismal Systems; Immune system; Toll-like receptor signaling pathway [PATH:hsa04620]
Human Diseases; Infectious diseases; Measles [PATH:hsa05162]
Human Diseases; Infectious diseases; Influenza A [PATH:hsa05164]

SSDB

Motif

Pfam:

LRR_8 LRR_4 LRR_1 TIR LRR_7 LRR_6 TIR_2 LRR_9

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

Xp22.3

AA seq 1049 aa
MVFPMWTLKRQILILFNIILISKLLGARWFPKTLPCDVTLDVPKNHVIVDCTDKHLTEIP
GGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVPIPLGSKNNMCIKRLQIKP
RSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFSIRKENLTELANIEILYLG
QNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTAVPTVLPSTLTELYLYNNMIAKI
QEDDFNNLNQLQILDLSGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALTELKVLRLHSN
SLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLDLSFNFELQVYRASM
NLSQAFSSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIANLSMFKQF
KRLKVIDLSVNKISPSGDSSEVGFCSNARTSVESYEPQVLEQLHYFRYDKYARSCRFKNK
EASFMSVNESCYKYGQTLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQP
LAELRYLDFSNNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQK
LMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKLEELDISKN
SLSFLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSN
CSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLL
HHNRFLCTCDAVWFVWWVNHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNL
ILFSLSISVSLFLMVMMTASHLYFWDVWYIYHFCKAKIKGYQRLISPDCCYDAFIVYDTK
DPAVTEWVLAELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDK
YAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQ
AHPYFWQCLKNALATDNHVAYSQVFKETV

NT seq 3150 nt +upstreamnt +downstreamnt
atggtgtttccaatgtggacactgaagagacaaattcttatcctttttaacataatccta
atttccaaactccttggggctagatggtttcctaaaactctgccctgtgatgtcactctg
gatgttccaaagaaccatgtgatcgtggactgcacagacaagcatttgacagaaattcct
ggaggtattcccacgaacaccacgaacctcaccctcaccattaaccacataccagacatc
tccccagcgtcctttcacagactggaccatctggtagagatcgatttcagatgcaactgt
gtacctattccactggggtcaaaaaacaacatgtgcatcaagaggctgcagattaaaccc
agaagctttagtggactcacttatttaaaatccctttacctggatggaaaccagctacta
gagataccgcagggcctcccgcctagcttacagcttctcagccttgaggccaacaacatc
ttttccatcagaaaagagaatctaacagaactggccaacatagaaatactctacctgggc
caaaactgttattatcgaaatccttgttatgtttcatattcaatagagaaagatgccttc
ctaaacttgacaaagttaaaagtgctctccctgaaagataacaatgtcacagccgtccct
actgttttgccatctactttaacagaactatatctctacaacaacatgattgcaaaaatc
caagaagatgattttaataacctcaaccaattacaaattcttgacctaagtggaaattgc
cctcgttgttataatgccccatttccttgtgcgccgtgtaaaaataattctcccctacag
atccctgtaaatgcttttgatgcgctgacagaattaaaagttttacgtctacacagtaac
tctcttcagcatgtgcccccaagatggtttaagaacatcaacaaactccaggaactggat
ctgtcccaaaacttcttggccaaagaaattggggatgctaaatttctgcattttctcccc
agcctcatccaattggatctgtctttcaattttgaacttcaggtctatcgtgcatctatg
aatctatcacaagcattttcttcactgaaaagcctgaaaattctgcggatcagaggatat
gtctttaaagagttgaaaagctttaacctctcgccattacataatcttcaaaatcttgaa
gttcttgatcttggcactaactttataaaaattgctaacctcagcatgtttaaacaattt
aaaagactgaaagtcatagatctttcagtgaataaaatatcaccttcaggagattcaagt
gaagttggcttctgctcaaatgccagaacttctgtagaaagttatgaaccccaggtcctg
gaacaattacattatttcagatatgataagtatgcaaggagttgcagattcaaaaacaaa
gaggcttctttcatgtctgttaatgaaagctgctacaagtatgggcagaccttggatcta
agtaaaaatagtatattttttgtcaagtcctctgattttcagcatctttctttcctcaaa
tgcctgaatctgtcaggaaatctcattagccaaactcttaatggcagtgaattccaacct
ttagcagagctgagatatttggacttctccaacaaccggcttgatttactccattcaaca
gcatttgaagagcttcacaaactggaagttctggatataagcagtaatagccattatttt
caatcagaaggaattactcatatgctaaactttaccaagaacctaaaggttctgcagaaa
ctgatgatgaacgacaatgacatctcttcctccaccagcaggaccatggagagtgagtct
cttagaactctggaattcagaggaaatcacttagatgttttatggagagaaggtgataac
agatacttacaattattcaagaatctgctaaaattagaggaattagacatctctaaaaat
tccctaagtttcttgccttctggagtttttgatggtatgcctccaaatctaaagaatctc
tctttggccaaaaatgggctcaaatctttcagttggaagaaactccagtgtctaaagaac
ctggaaactttggacctcagccacaaccaactgaccactgtccctgagagattatccaac
tgttccagaagcctcaagaatctgattcttaagaataatcaaatcaggagtctgacgaag
tattttctacaagatgccttccagttgcgatatctggatctcagctcaaataaaatccag
atgatccaaaagaccagcttcccagaaaatgtcctcaacaatctgaagatgttgcttttg
catcataatcggtttctgtgcacctgtgatgctgtgtggtttgtctggtgggttaaccat
acggaggtgactattccttacctggccacagatgtgacttgtgtggggccaggagcacac
aagggccaaagtgtgatctccctggatctgtacacctgtgagttagatctgactaacctg
attctgttctcactttccatatctgtatctctctttctcatggtgatgatgacagcaagt
cacctctatttctgggatgtgtggtatatttaccatttctgtaaggccaagataaagggg
tatcagcgtctaatatcaccagactgttgctatgatgcttttattgtgtatgacactaaa
gacccagctgtgaccgagtgggttttggctgagctggtggccaaactggaagacccaaga
gagaaacattttaatttatgtctcgaggaaagggactggttaccagggcagccagttctg
gaaaacctttcccagagcatacagcttagcaaaaagacagtgtttgtgatgacagacaag
tatgcaaagactgaaaattttaagatagcattttacttgtcccatcagaggctcatggat
gaaaaagttgatgtgattatcttgatatttcttgagaagccctttcagaagtccaagttc
ctccagctccggaaaaggctctgtgggagttctgtccttgagtggccaacaaacccgcaa
gctcacccatacttctggcagtgtctaaagaacgccctggccacagacaatcatgtggcc
tatagtcaggtgttcaaggaaacggtctag

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Drug (3)   
   KEGG DRUG (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (8)   
   Pfam (8)   
All databases (57)   

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