KEGG T01001: 51478

Homo sapiens (human): 51478

Entry

51478 CDS T01001

Gene name

HSD17B7, PRAP, SDR37C1

Definition

hydroxysteroid (17-beta) dehydrogenase 7 (EC:1.1.1.62 1.1.1.270)

Orthology

K13373

17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]

Organism

hsa Homo sapiens (human)

Pathway

hsa00100	Steroid biosynthesis
hsa00140	Steroid hormone biosynthesis
hsa01100	Metabolic pathways
hsa04913	Ovarian steroidogenesis

Module

hsa_M00101

Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol

Class

Metabolism; Lipid metabolism; Steroid biosynthesis [PATH:hsa00100]
Metabolism; Lipid metabolism; Steroid hormone biosynthesis [PATH:hsa00140]
Organismal Systems; Endocrine system; Ovarian Steroidogenesis [PATH:hsa04913]

SSDB

Motif

Pfam:

adh_short KR Epimerase NAD_binding_10 Saccharop_dh Eno-Rase_NADH_b 3Beta_HSD Polysacc_synt_2

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

UniProt:

Position

1q23

AA seq 341 aa
MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV
QVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTA
EGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFS
LEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIW
TLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYIMTQ
KMDLDEDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL

NT seq 1026 nt +upstreamnt +downstreamnt
atgcgaaaggtggttttgatcaccggggctagcagtggcattggcctggccctctgcaag
cggctgctggcggaagatgatgagcttcatctgtgtttggcgtgcaggaacatgagcaag
gcagaagctgtctgtgctgctctgctggcctctcaccccactgctgaggtcaccattgtc
caggtggatgtcagcaacctgcagtcggtcttccgggcctccaaggaacttaagcaaagg
tttcagagattagactgtatatatctaaatgctgggatcatgcctaatccacaactaaat
atcaaagcacttttctttggcctcttttcaagaaaagtgattcatatgttctccacagct
gaaggcctgctgacccagggtgataagatcactgctgatggacttcaggaggtgtttgag
accaatgtctttggccattttatcctgattcgggaactggagcctctcctctgtcacagt
gacaatccatctcagctcatctggacatcatctcgcagtgcaaggaaatctaatttcagc
ctcgaggacttccagcacagcaaaggcaaggaaccctacagctcttccaaatatgccact
gaccttttgagtgtggctttgaacaggaacttcaaccagcagggtctctattccaatgtg
gcctgtccaggtacagcattgaccaatttgacatatggaattctgcctccgtttatatgg
acgctgttgatgccggcaatattgctacttcgcttttttgcaaatgcattcactttgaca
ccatataatggaacagaagctctggtatggcttttccaccaaaagcctgaatctctcaat
cctctgatcaaatatctgagtgccaccactggctttggaagaaattacattatgacccag
aagatggacctagatgaagacactgctgaaaaattttatcaaaagttactggaactggaa
aagcacattagggtcactattcaaaaaacagataatcaggccaggctcagtggctcatgc
ctataa

All links

Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (12)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
Protein domain (8)   
   Pfam (8)   
All databases (81)   

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