| Entry |
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| Gene name |
PFKFB1, F6PK, HL2K, PFRX
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| Definition |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (EC:2.7.1.105 3.1.3.46)
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| Orthology |
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| Organism |
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| Pathway |
| Fructose and mannose metabolism | | HIF-1 signaling pathway |
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| Class |
Metabolism; Carbohydrate metabolism; Fructose and mannose metabolism [PATH: hsa00051]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH: hsa04066]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| Structure |
PDB: |
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| Position |
Xp11.21
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| AA seq |
449 aa  
MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
KLTRYLNWIGTPTKDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSL
ILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEV
NYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGES
ELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQ
WKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMEL
ERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVE
AVNTHREKPENVDITREPEEALDTVPAHY |
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| NT seq |
1350 nt  +upstreamnt +downstreamnt
atgtctccagagatgggagagctcacccaaaccaggttgcagaagatctggattccacac
agcagcggcagcagcaggctgcaacggagaaggggctcatccataccccagtttaccaat
tcccccacaatggtgatcatggtgggtttaccagctcgaggcaagacctatatctccaca
aagctcacacgatatctcaactggataggaacaccaactaaagacaacatggaagccctg
caaatcaggaagcagtgcgccctggcagccctgaaggatgttcacaactatctcagccat
gaggaaggtcatgttgcggtttttgatgccaccaacactaccagagaacgacggtcactg
atcctgcagtttgcaaaagaacatggttacaaggtgtttttcattgagtccatttgtaat
gaccctggcataattgcagaaaacatcaggcaagtgaaacttggcagccctgattatata
gactgtgaccgggaaaaggttctggaagactttctaaagagaattgagtgctatgaggtc
aactaccaacccttggatgaggaactggacagccacctgtcctacatcaagatcttcgac
gtgggcacacgctacatggtgaaccgagtgcaggatcacatccagagccgcacagtctac
tacctcatgaatatccatgtcacacctcgctccatctacctttgccgacatggcgagagt
gaactcaacatcagaggccgcatcggaggtgactctggcctctcagttcgcggcaagcag
tatgcctatgccctggccaacttcattcagtcccagggcatcagctccctgaaggtgtgg
accagtcacatgaagaggaccatccagacagctgaggccctgggtgtcccctatgagcag
tggaaggccctgaatgagattgatgcgggtgtctgtgaggagatgacctatgaagaaatc
caggaacattaccctgaagaatttgcactgcgagaccaagataaatatcgctaccgctat
cccaagggagagtcctatgaggatctggttcagcgtctggagccagtgataatggagcta
gaacgacaggagaatgtactggtgatctgccaccaggctgtcatgcggtgcctcctggcc
tatttcctggataaaagttcagatgagcttccatatctcaagtgccctctgcacacagtg
ctcaaactcactcctgtggcttatggctgcaaagtggaatccatctacctgaatgtggag
gccgtgaacacacaccgggagaagcctgagaatgtggacatcacccgggaacctgaggaa
gccctggatactgtcccagcccactactga |
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