KEGG   Homo sapiens (human): 5209Help
Entry
5209              CDS       T01001                                 

Gene name
PFKFB3, IPFK2, PFK2
Definition
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (EC:2.7.1.105 3.1.3.46)
Orthology
K01103  
6-phosphofructo-2-kinase / fructose-2,6-bisphosphatase [EC:2.7.1.105 3.1.3.46]
Organism
hsa  Homo sapiens (human)
Pathway
Fructose and mannose metabolism
HIF-1 signaling pathway
AMPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    5209 (PFKFB3)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    5209 (PFKFB3)
   04152 AMPK signaling pathway
    5209 (PFKFB3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.105  6-phosphofructo-2-kinase
     5209 (PFKFB3)
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.46  fructose-2,6-bisphosphate 2-phosphatase
     5209 (PFKFB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
10p15.1
AA seq 500 aa AA seqDB search
MPFRKACGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVK
QYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHF
AKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQP
LDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHN
LQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKA
LNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQ
ENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVC
THRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPT
QLPGQNMKGSRSSADSSRKH
NT seq 1503 nt NT seq  +upstreamnt  +downstreamnt
atgcccttcaggaaagcctgtgggccaaagctgaccaactcccccaccgtcatcgtcatg
gtgggcctccccgcccggggcaagacctacatctccaagaagctgactcgctacctcaac
tggattggcgtccccacaaaagtgttcaacgtcggggagtatcgccgggaggctgtgaag
cagtacagctcctacaacttcttccgccccgacaatgaggaagccatgaaagtccggaag
caatgtgccttagctgccttgagagatgtcaaaagctacctggcgaaagaagggggacaa
attgcggttttcgatgccaccaatactactagagagaggagacacatgatccttcatttt
gccaaagaaaatgactttaaggcgtttttcatcgagtcggtgtgcgacgaccctacagtt
gtggcctccaatatcatggaagttaaaatctccagcccggattacaaagactgcaactcg
gcagaagccatggacgacttcatgaagaggatcagttgctatgaagccagctaccagccc
ctcgaccccgacaaatgcgacagggacttgtcgctgatcaaggtgattgacgtgggccgg
aggttcctggtgaaccgggtgcaggaccacatccagagccgcatcgtgtactacctgatg
aacatccacgtgcagccgcgtaccatctacctgtgccggcacggcgagaacgagcacaac
ctccagggccgcatcgggggcgactcaggcctgtccagccggggcaagaagtttgccagt
gctctgagcaagttcgtggaggagcagaacctgaaggacctgcgcgtgtggaccagccag
ctgaagagcaccatccagacggccgaggcgctgcggctgccctacgagcagtggaaggcg
ctcaatgagatcgacgcgggcgtctgtgaggagctgacctacgaggagatcagggacacc
taccctgaggagtatgcgctgcgggagcaggacaagtactattaccgctaccccaccggg
gagtcctaccaggacctggtccagcgcttggagccagtgatcatggagctggagcggcag
gagaatgtgctggtcatctgccaccaggccgtcctgcgctgcctgcttgcctacttcctg
gataagagtgcagaggagatgccctacctgaaatgccctcttcacaccgtcctgaaactg
acgcctgtcgcttatggctgccgtgtggaatccatctacctgaacgtggagtccgtctgc
acacaccgggagaggtcagaggatgcaaagaagggacctaacccgctcatgagacgcaat
agtgtcaccccgctagccagccccgaacccaccaaaaagcctcgcatcaacagctttgag
gagcatgtggcctccacctcggccgccctgcccagctgcctgcccccggaggtgcccacg
cagctgcctggacaaaacatgaaaggctcccggagcagcgctgactcctccaggaaacac
tga

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