KEGG   Homo sapiens (human): 5211Help
Entry
5211              CDS       T01001                                 

Gene name
PFKL, PFK-B
Definition
phosphofructokinase, liver (EC:2.7.1.11)
Orthology
K00850  
6-phosphofructokinase 1 [EC:2.7.1.11]
Organism
hsa  Homo sapiens (human)
Pathway
Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Fructose and mannose metabolism
Galactose metabolism
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
HIF-1 signaling pathway
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Class
Metabolism; Overview; Carbon metabolism [PATH:hsa01200]
Metabolism; Overview; Biosynthesis of amino acids [PATH:hsa01230]
Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:hsa00010]
Metabolism; Carbohydrate metabolism; Pentose phosphate pathway [PATH:hsa00030]
Metabolism; Carbohydrate metabolism; Fructose and mannose metabolism [PATH:hsa00051]
Metabolism; Carbohydrate metabolism; Galactose metabolism [PATH:hsa00052]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:hsa04066]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
21q22.3
AA seq 780 aa AA seqDB search
MAAVDLEKLRASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVE
GGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDG
SLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDS
ALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWE
NFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQ
RGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQK
AMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRS
AVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESI
VENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLG
SDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFN
IHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGH
LQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFS
PVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRRTLSMDKGF
NT seq 2343 nt NT seq  +upstreamnt  +downstreamnt
atggccgcggtggacctggagaagctgcgggcgtcgggcgcgggcaaggccatcggcgtc
ctgaccagcggcggcgacgcgcaaggcatgaacgctgctgtccgggctgtgacgcgcatg
ggcatttatgtgggtgccaaagtcttcctcatctacgagggctatgagggcctcgtggag
ggaggtgagaacatcaagcaggccaactggctgagcgtctccaacatcatccagctgggc
ggcactatcattggcagcgctcgctgcaaggcctttaccaccagggaggggcgccgggca
gcggcctacaacctggtccagcacggcatcaccaacctgtgcgtcatcggcggggatggc
agcctcacaggtgccaacatcttccgcagcgagtggggcagcctgctggaggagctggtg
gcggaaggtaagatctcagagactacagcccggacctactcgcacctgaacatcgcgggc
ctagtgggctccatcgataacgacttctgcggcaccgacatgaccatcggcacggactcg
gccctccaccgcatcatggaggtcatcgatgccatcaccaccactgcccagagccaccag
aggaccttcgtgctggaagtgatgggccggcactgcgggtacctggcgctggtatctgca
ctggcctcaggggccgactggctgttcatccccgaggctccacccgaggacggctgggag
aacttcatgtgtgagaggctgggtgagactcggagccgtgggtcccgactgaacatcatc
atcatcgctgagggtgccattgaccgcaacgggaagcccatctcgtccagctacgtgaag
gacctggtggttcagaggctgggcttcgacacccgtgtaactgtgctgggccacgtgcag
cggggagggacgccctctgccttcgaccggatcctgagcagcaagatgggcatggaggcg
gtgatggcgctgctggaagccacgcctgacacgccggcctgcgtggtcaccctctcgggg
aaccagtcagtgcggctgcccctcatggagtgcgtgcagatgaccaaggaagtgcagaaa
gccatggatgacaagaggtttgacgaggccacccagctccgtggtgggagcttcgagaac
aactggaacatttacaagctcctcgcccaccagaagccccccaaggagaagtctaacttc
tccctggccatcctgaatgtgggggccccggcggctggcatgaatgcggccgtgcgctcg
gcggtgcggaccggcatctcccatggacacacagtatacgtggtgcacgatggcttcgaa
ggcctagccaagggtcaggtgcaagaagtaggctggcacgacgtggccggctggttgggg
cgtggtggctccatgctggggaccaagaggaccctgcccaagggccagctggagtccatt
gtggagaacatccgcatctatggtattcacgccctgctggtggtcggtgggtttgaggcc
tatgaaggggtgctgcagctggtggaggctcgcgggcgctacgaggagctctgcatcgtc
atgtgtgtcatcccagccaccatcagcaacaacgtccctggcaccgacttcagcctgggc
tccgacactgctgtaaatgccgccatggagagctgtgaccgcatcaaacagtctgcctcg
gggaccaagcgccgtgtgttcatcgtggagaccatggggggttactgtggctacctggcc
accgtgactggcattgctgtgggggccgacgccgcctacgtcttcgaggaccctttcaac
atccacgacttaaaggtcaacgtggagcacatgacggagaagatgaagacagacattcag
aggggcctggtgctgcggaacgagaagtgccatgactactacaccacggagttcctgtac
aacctgtactcatcagagggcaagggcgtcttcgactgcaggaccaatgtcctgggccac
ctgcagcagggtggcgctccaaccccctttgaccggaactatgggaccaagctgggggtg
aaggccatgctgtggttgtcggagaagctgcgcgaggtttaccgcaagggacgggtgttc
gccaatgccccagactcggcctgcgtgatcggcctgaagaagaaggcggtggccttcagc
cccgtcactgagctcaagaaagacactgatttcgagcaccgcatgccacgggagcagtgg
tggctgagcctgcggctcatgctgaagatgctggcacaataccgcatcagtatggccgcc
tacgtgtcaggggagctggagcacgtgacccgccgcaccctgagcatggacaagggcttc
tga

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