KEGG   Homo sapiens (human): 5214Help
Entry
5214              CDS       T01001                                 

Gene name
PFKP, ATP-PFK, PFK-C, PFK-P, PFKF
Definition
(RefSeq) phosphofructokinase, platelet (EC:2.7.1.11)
  KO
K00850  
6-phosphofructokinase 1 [EC:2.7.1.11]
Organism
hsa  Homo sapiens (human)
Pathway
Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Fructose and mannose metabolism
Galactose metabolism
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
RNA degradation
AMPK signaling pathway
Thyroid hormone signaling pathway
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    5214 (PFKP)
   01230 Biosynthesis of amino acids
    5214 (PFKP)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    5214 (PFKP)
   00030 Pentose phosphate pathway
    5214 (PFKP)
   00051 Fructose and mannose metabolism
    5214 (PFKP)
   00052 Galactose metabolism
    5214 (PFKP)
 Genetic Information Processing
  Folding, sorting and degradation
   03018 RNA degradation
    5214 (PFKP)
 Environmental Information Processing
  Signal transduction
   04152 AMPK signaling pathway
    5214 (PFKP)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    5214 (PFKP)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    5214 (PFKP)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.11  6-phosphofructokinase
     5214 (PFKP)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     5214 (PFKP)
Messenger RNA biogenesis [BR:hsa03019]
 Prokaryotic Type
  Bacterial mRNA degradation factors
   RNA degradosome components
    Other RNA degradosome components
     5214 (PFKP)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
10p15.3-p15.2
AA seq 784 aa AA seqDB search
MDADDSRAPKGSLRKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFI
YEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGIT
NLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCG
TDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLP
ESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDT
RVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMEC
VQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGA
PAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTK
RVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVS
NNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGA
DAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKG
VFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGRGKKFTTDDSICVL
GISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ
PWSV
NT seq 2355 nt NT seq  +upstreamnt  +downstreamnt
atggacgcggacgactcccgggcccccaagggctccttgcggaagttcctggagcacctc
tccggggccggcaaggccatcggcgtgctgaccagcggcggggatgctcaaggtatgaac
gctgccgtccgtgccgtggtgcgcatgggtatctacgtgggggccaaggtgtacttcatc
tacgagggctaccagggcatggtggacggaggctcaaacatcgcagaggccgactgggag
agtgtctccagcatcctgcaagtgggcgggacgatcattggcagtgcgcggtgccaggcc
ttccgcacgcgggaaggccgcctgaaggctgcttgcaacctgctgcagcgcggcatcacc
aacctgtgtgtgatcggcggggacgggagcctcaccggggccaacctcttccggaaggag
tggagtgggctgctggaggagctggccaggaacggccagatcgataaggaggccgtgcag
aagtacgcctacctcaacgtggtgggcatggtgggctccatcgacaatgatttctgcggc
accgacatgaccatcggcacggactccgccctgcacaggatcatcgaggtcgtcgacgcc
atcatgaccacggcccagagccaccagaggaccttcgttctggaggtgatgggacgacac
tgtgggtacctggccctggtgagtgccttggcctgcggtgcggactgggtgttccttcca
gaatctccaccagaggaaggctgggaggagcagatgtgtgtcaaactctcggagaaccgt
gcccggaaaaaaaggctgaatattattattgtggctgaaggagcaattgatacccaaaat
aaacccatcacctctgagaaaatcaaagagcttgtcgtcacgcagctgggctatgacaca
cgtgtgaccatcctcgggcacgtgcagagaggagggaccccttcggcattcgacaggatc
ttggccagccgcatgggagtggaggcagtcatcgccttgctagaggccaccccggacacc
ccagcttgcgtcgtgtcactgaacgggaaccacgccgtgcgcctgccgctgatggagtgc
gtgcagatgactcaggatgtgcagaaggcgatggacgagaggagatttcaagatgcggtt
cgactccgagggaggagctttgcgggcaacctgaacacctacaagcgacttgccatcaag
ctgccggatgatcagatcccaaagaccaattgcaacgtagctgtcatcaacgtgggggca
cccgcggctgggatgaacgcagccgtacgctcagctgtgcgcgtgggcattgccgacggc
cacaggatgctcgccatctatgatggctttgacggcttcgccaagggccagatcaaagaa
atcggctggacagatgtcgggggctggaccggccaaggaggctccattcttgggacaaaa
cgcgttctcccggggaagtacttggaagagatcgccacacagatgcgcacgcacagcatc
aacgcgctgctgatcatcggtggattcgaggcctacctgggactcctggagctgtcagcc
gcccgggagaagcacgaggagttctgtgtccccatggtcatggttcccgctactgtgtcc
aacaatgtgccgggttccgatttcagcatcggggcagacaccgccctgaacactatcacc
gacacctgcgaccgcatcaagcagtccgccagcggaaccaagcggcgcgtgttcatcatc
gagaccatgggcggctactgtggctacctggccaacatgggggggctcgcggccggagct
gatgccgcatacattttcgaagagcccttcgacatcagggatctgcagtccaacgtggag
cacctgacggagaaaatgaagaccaccatccagagaggccttgtgctcagaaatgagagc
tgcagtgaaaactacaccaccgacttcatttaccagctgtattcagaagagggcaaaggc
gtgtttgactgcaggaagaacgtgctgggtcacatgcagcagggtggggcaccctctcca
tttgatagaaactttggaaccaaaatctctgccagagctatggagtggatcactgcaaaa
ctcaaggaggcccggggcagaggaaaaaaatttaccaccgatgattccatttgtgtgctg
ggaataagcaaaagaaacgttatttttcaacctgtggcagagctgaagaagcaaacggat
tttgagcacaggattcccaaagaacagtggtggctcaagctacggcccctcatgaaaatc
ctggccaagtacaaggccagctatgacgtgtcggactcaggccagctggaacatgtgcag
ccctggagtgtctga

DBGET integrated database retrieval system