| Entry |
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| Gene name |
PGAM1, HEL-S-35, PGAM-B, PGAMA
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| Definition |
(RefSeq) phosphoglycerate mutase 1
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| KO |
| K01834 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] |
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| Organism |
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| Pathway |
| hsa00260 | Glycine, serine and threonine metabolism |
| hsa05230 | Central carbon metabolism in cancer |
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| Module |
| hsa_M00001 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate |
| hsa_M00002 | Glycolysis, core module involving three-carbon compounds |
| hsa_M00003 | Gluconeogenesis, oxaloacetate => fructose-6P |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
Metabolism
Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
5223 (PGAM1)
Amino acid metabolism
00260 Glycine, serine and threonine metabolism
5223 (PGAM1)
Organismal Systems
Endocrine system
04922 Glucagon signaling pathway
5223 (PGAM1)
Human Diseases
Cancers
05230 Central carbon metabolism in cancer
5223 (PGAM1)
Enzymes [BR:hsa01000]
5. Isomerases
5.4 Intramolecular transferases
5.4.2 Phosphotransferases (phosphomutases)
5.4.2.11 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
5223 (PGAM1)
Membrane trafficking [BR:hsa04131]
Autophagy
Chaperone mediated autophagy (CMA)
Selective cargos
5223 (PGAM1)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of bladder cancer cells
5223 (PGAM1)
Exosomal proteins of melanoma cells
5223 (PGAM1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
10q24.1
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| AA seq |
254 aa  
MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ
KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR
VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVR
KAMEAVAAQGKAKK |
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| NT seq |
765 nt  +upstreamnt +downstreamnt
atggccgcctacaaactggtgctgatccggcacggcgagagcgcatggaacctggagaac
cgcttcagcggctggtacgacgccgacctgagcccggcgggccacgaggaggcgaagcgc
ggcgggcaggcgctacgagatgctggctatgagtttgacatctgcttcacctcagtgcag
aagagagcgatccggaccctctggacagtgctagatgccattgatcagatgtggctgcca
gtggtgaggacttggcgcctcaatgagcggcactatgggggtctaaccggtctcaataaa
gcagaaactgctgcaaagcatggtgaggcccaggtgaagatctggaggcgctcctatgat
gtcccaccacctccgatggagcccgaccatcctttctacagcaacatcagtaaggatcgc
aggtatgcagacctcacagaagatcagctaccctcctgtgagagtctgaaggatactatt
gccagagctctgcccttctggaatgaagaaatagttccccagatcaaggaggggaaacgt
gtactgattgcagcccatggcaacagcctccggggcattgtcaagcatctggagggtctc
tctgaagaggctatcatggagctgaacctgccgactggtattcccattgtctatgaattg
gacaagaacttgaagcctatcaagcccatgcagtttctgggggatgaagagacggtgcgc
aaagccatggaagctgtggctgcccagggcaaggccaagaagtga |
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