KEGG T01001: 5226

Homo sapiens (human): 5226

Entry

5226 CDS T01001

Gene name

PGD, 6PGD

Definition

phosphogluconate dehydrogenase (EC:1.1.1.44)

Orthology

K00033

6-phosphogluconate dehydrogenase [EC:1.1.1.44]

Organism

hsa Homo sapiens (human)

Pathway

hsa00030	Pentose phosphate pathway
hsa00480	Glutathione metabolism
hsa01100	Metabolic pathways

Module

hsa_M00004	Pentose phosphate pathway (Pentose phosphate cycle)
hsa_M00006	Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P

Class

Metabolism; Carbohydrate metabolism; Pentose phosphate pathway [PATH:hsa00030]
Metabolism; Metabolism of other amino acids; Glutathione metabolism [PATH:hsa00480]

SSDB

Motif

Pfam:

6PGD NAD_binding_2 NAD_binding_11 F420_oxidored ApbA

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

4GWG 4GWK 2JKV

Position

1p36.22

AA seq 483 aa
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE
MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG
ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG
HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL
KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA
SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL
MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM
PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS
YNA

NT seq 1452 nt +upstreamnt +downstreamnt
atggcccaagctgacatcgcgctgatcggattggccgtcatgggccagaacttaattctg
aacatgaatgaccacggctttgtggtctgtgcttttaataggactgtctccaaagttgat
gatttcttggccaatgaggcaaagggaaccaaagtggtgggtgcccagtccctgaaagag
atggtctccaagctgaagaagccccggcggatcatcctcctggtgaaggctgggcaagct
gtggatgatttcatcgagaaattggtaccattgttggatactggtgacatcatcattgac
ggaggaaattctgaatatagggacaccacaagacggtgccgagacctcaaggccaaggga
attttatttgtggggagcggagtcagtggtggagaggaaggggcccggtatggcccatcg
ctcatgccaggagggaacaaagaagcgtggccccacatcaagaccatcttccaaggcatt
gctgcaaaagtgggaactggagaaccctgctgtgactgggtgggagatgagggagcaggc
cacttcgtgaagatggtgcacaacgggatagagtatggggacatgcagctgatctgtgag
gcataccacctgatgaaagacgtgctgggcatggcgcaggacgagatggcccaggccttt
gaggattggaataagacagagctagactcattcctgattgaaatcacagccaatattctc
aagttccaagacaccgatggcaaacacctgctgccaaagatcagggacagcgcggggcag
aagggcacagggaagtggaccgccatctccgccctggaatacggcgtacccgtcaccctc
attggagaagctgtctttgctcggtgcttatcatctctgaaggatgagagaattcaagct
agcaaaaagctgaagggtccccagaagttccagtttgatggtgataagaaatcattcctg
gaggacattcggaaggcactctacgcttccaagatcatctcttacgctcaaggctttatg
ctgctaaggcaggcagccaccgagtttggctggactctcaattatggtggcatcgccctg
atgtggagagggggctgcatcattagaagtgtattcctaggaaagataaaggatgcattt
gatcgaaacccggaacttcagaacctcctactggacgacttctttaagtcagctgttgaa
aactgccaggactcctggcggcgggcagtcagcactggggtccaggctggcattcccatg
ccctgttttaccactgccctctccttctatgacgggtacagacatgagatgcttccagcc
agcctcatccaggctcagcgggattacttcggggctcacacctatgaactcttggccaaa
ccagggcagtttatccacaccaactggacaggccatggtggcaccgtgtcatcctcgtca
tacaatgcctga

All links

Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (3)   
   PDB (3)   
Protein domain (5)   
   Pfam (5)   
All databases (61)   

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