KEGG T01001: 5292

Homo sapiens (human): 5292

Entry

5292 CDS T01001

Gene name

PIM1, PIM

Definition

pim-1 oncogene (EC:2.7.11.1)

Orthology

K04702

proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa04630	Jak-STAT signaling pathway
hsa05221	Acute myeloid leukemia

Class

Environmental Information Processing; Signal transduction; Jak-STAT signaling pathway [PATH:hsa04630]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:hsa05221]

SSDB

Motif

Pfam:

Pkinase Pkinase_Tyr Kinase-like Kdo APH Seadorna_VP7 Choline_kinase

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

3A99 3R04 1XWS 3VBQ 4DTK 3F2A 2C3I 2BZH 2BZI 4ALW 3R02 3C4E 4GW8 3BGQ 2O63 1YXT 1YXV 1YXX 1YWV 3CY2 3VBX 2BZJ 3VBV 3UMW 3R00 3JYA 3CXW 1XQZ 1XR1 2XJ1 3CY3 1YHS 3UIX 3QF9 2XIY 2XJ2 2OI4 1YXS 2XIZ 3VC4 3VBT 2O3P 1YXU 3VBY 4AS0 4A7C 3MA3 3JPV 3BWF 2XIX 3JY0 3BGZ 1YI4 2O64 2BZK 3VBW 2OBJ 1YI3 3UMX 2BIL 4ALV 4ALU 3T9I 3R01 3DCV 4ENX 4ENY 3JXW 3BGP 2O65 2XJ0 2J2I 2BIK

Position

6p21.2

AA seq 404 aa
MPHEPHEPLTPPFSALPDPAGAPSRRQSRQRPQLSSDSPSAFRASRSHSRNATRSHSHSH
SPRHSLRHSPGSGSCGSSSGHRPCADILEVGMLLSKINSLAHLRAAPCNDLHATKLAPGK
EKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPME
VVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFW
QVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSP
PEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRW
CLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPSK

NT seq 1215 nt +upstreamnt +downstreamnt
ctgccgcacgagccccacgagccgctcaccccgccgttctcagcgctgcccgaccccgct
ggcgcgccctcccgccgccagtcccggcagcgccctcagttgtcctccgactcgccctcg
gccttccgcgccagccgcagccacagccgcaacgccacccgcagccacagccacagccac
agccccaggcatagccttcggcacagccccggctccggctcctgcggcagctcctctggg
caccgtccctgcgccgacatcctggaggttgggatgctcttgtccaaaatcaactcgctt
gcccacctgcgcgccgcgccctgcaacgacctgcacgccaccaagctggcgcccggcaag
gagaaggagcccctggagtcgcagtaccaggtgggcccgctactgggcagcggcggcttc
ggctcggtctactcaggcatccgcgtctccgacaacttgccggtggccatcaaacacgtg
gagaaggaccggatttccgactggggagagctgcctaatggcactcgagtgcccatggaa
gtggtcctgctgaagaaggtgagctcgggtttctccggcgtcattaggctcctggactgg
ttcgagaggcccgacagtttcgtcctgatcctggagaggcccgagccggtgcaagatctc
ttcgacttcatcacggaaaggggagccctgcaagaggagctggcccgcagcttcttctgg
caggtgctggaggccgtgcggcactgccacaactgcggggtgctccaccgcgacatcaag
gacgaaaacatccttatcgacctcaatcgcggcgagctcaagctcatcgacttcgggtcg
ggggcgctgctcaaggacaccgtctacacggacttcgatgggacccgagtgtatagccct
ccagagtggatccgctaccatcgctaccatggcaggtcggcggcagtctggtccctgggg
atcctgctgtatgatatggtgtgtggagatattcctttcgagcatgacgaagagatcatc
aggggccaggttttcttcaggcagagggtctcttcagaatgtcagcatctcattagatgg
tgcttggccctgagaccatcagataggccaaccttcgaagaaatccagaaccatccatgg
atgcaagatgttctcctgccccaggaaactgctgagatccacctccacagcctgtcgccg
gggcccagcaaatag

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
3D Structure (73)   
   PDB (73)   
Protein domain (7)   
   Pfam (7)   
All databases (128)   

Download RDF

DBGET integrated database retrieval system