KEGG T01001: 5298

Homo sapiens (human): 5298

Entry

5298 CDS T01001

Gene name

PI4KB, NPIK, PI4K-BETA, PI4K92, PI4KBETA, PI4KIIIBETA, PIK4CB

Definition

phosphatidylinositol 4-kinase, catalytic, beta (EC:2.7.1.67)

Orthology

K00888

phosphatidylinositol 4-kinase [EC:2.7.1.67]

Organism

hsa Homo sapiens (human)

Pathway

hsa00562	Inositol phosphate metabolism
hsa01100	Metabolic pathways
hsa04070	Phosphatidylinositol signaling system

Module

hsa_M00130

Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4

Class

Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:hsa00562]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:hsa04070]

SSDB

Motif

Pfam:

PI3_PI4_kinase DUF4135

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

1q21

AA seq 801 aa
MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVK
LLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAVASGTAKGARRRR
QNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLL
NMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLI
LSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVEN
EDEPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFD
HHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENRIRSTRSVENLPEC
GITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNISQFSVDSITSQES
KEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEKVRRIREGSPYGHLPN
WRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVN
AVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNG
NILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQ
GLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDG
SMRSITTKLYDGFQYLTNGIM

NT seq 2406 nt +upstreamnt +downstreamnt
atgggagatacagtagtggagcctgcccccttgaagccaacttctgagcccacttctggc
ccaccagggaataatggggggtccctgctaagtgtcatcacggagggggtcggggaacta
tcagtgattgaccctgaggtggcccagaaggcctgccaggaggtgttggagaaagtcaag
cttttgcatggaggcgtggcagtctctagcagaggcaccccactggagttggtcaatggg
gatggtgtggacagtgagatccgttgcctagatgatccacctgcccagatcagggaggag
gaagatgagatgggggccgctgtggcctcaggcacagccaaaggagcaagaagacggcgg
cagaacaactcagctaaacagtcttggctgctgaggctgtttgagtcaaaactgtttgac
atctccatggccatttcatacctgtataactccaaggagcctggagtacaagcctacatt
ggcaaccggctcttctgctttcgcaacgaggacgtggacttctatctgccccagttgctt
aacatgtacatccacatggatgaggacgtgggtgatgccattaagccctacatagtccac
cgttgccgccagagcattaacttttccctccagtgtgccctgttgcttggggcctattct
tcagacatgcacatttccactcaacgacactcccgtgggaccaagctacggaagctgatc
ctctcagatgagctaaagccagctcacaggaagagggagctgccctccttgagcccggcc
cctgacacagggctgtctccctccaaaaggactcaccagcgctctaagtcagatgccact
gccagcataagtctcagcagcaacctgaaacgaacagccagcaaccctaaagtggagaat
gaggatgagcctgttcgactggctcctgagagagaattcatcaagtccctgatggcgatc
ggcaagcggctggccacgctccccaccaaagagcagaaaacacagaggctgatctcagag
ctctccctgctcaaccataagctccctgcccgagtctggctgcccactgctggctttgac
caccacgtggtccgtgtaccccacacacaggctgttgtcctcaactccaaggacaaggct
ccctacctgatttatgtggaagtccttgaatgtgaaaactttgacaccaccagtgtccct
gcccggatccccgagaaccgaattcggagtacgaggtccgtagaaaacttgcccgaatgt
ggtattacccatgagcagcgagctggcagcttcagcactgtgcccaactatgacaacgat
gatgaggcctggtcggtggatgacataggcgagctgcaagtggagctccccgaagtgcat
accaacagctgtgacaacatctcccagttctctgtggacagcatcaccagccaggagagc
aaggagcctgtgttcattgcagcaggggacatccgccggcgcctttcggaacagctggct
cataccccgacagccttcaaacgagacccagaagatccttctgcagttgctctcaaagag
ccctggcaggagaaagtacggcggatcagagagggctccccctacggccatctccccaat
tggcggctcctgtcagtcattgtcaagtgtggggatgaccttcggcaagagcttctggcc
tttcaggtgttgaagcaactgcagtccatttgggaacaggagcgagtgcccctttggatc
aagccatacaagattcttgtgatttcggctgatagtggcatgattgaaccagtggtcaat
gctgtgtccatccatcaggtgaagaaacagtcacagctctccttgctcgattacttccta
caggagcacggcagttacaccactgaggcattcctcagtgcacagcgcaattttgtgcaa
agttgtgctgggtactgcttggtctgctacctgctgcaagtcaaggacagacacaatggg
aatatccttttggacgcagaaggccacatcatccacatcgactttggcttcatcctctcc
agctcaccccgaaatctgggctttgagacgtcagcctttaagctgaccacagagtttgtg
gatgtgatgggcggcctggatggcgacatgttcaactactataagatgctgatgctgcaa
gggctgattgccgctcggaaacacatggacaaggtggtgcagatcgtggagatcatgcag
caaggttctcagcttccttgcttccatggctccagcaccattcgaaacctcaaagagagg
ttccacatgagcatgactgaggagcagctgcagctgctggtggagcagatggtggatggc
agtatgcggtctatcaccaccaaactctatgacggcttccagtacctcaccaacggcatc
atgtga

All links

Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (7)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (26)   
   RefSeq(nuc) (4)   
   GenBank (11)   
   EMBL (11)   
Protein domain (2)   
   Pfam (2)   
All databases (60)   

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