| Entry |
|
|---|
| Gene name |
PLD2, PLD1C
|
|---|
| Definition |
(RefSeq) phospholipase D2
|
|---|
| KO |
|
|---|
| Organism |
|
|---|
| Pathway |
| Glycerophospholipid metabolism | | Ether lipid metabolism | | Metabolic pathways | | Ras signaling pathway | | cAMP signaling pathway | | Sphingolipid signaling pathway | | Phospholipase D signaling pathway | | Endocytosis | | Fc gamma R-mediated phagocytosis | | Glutamatergic synapse | | GnRH signaling pathway | | Choline metabolism in cancer |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:hsa00001]
Metabolism
Lipid metabolism
00564 Glycerophospholipid metabolism
5338 (PLD2)
00565 Ether lipid metabolism
5338 (PLD2)
Environmental Information Processing
Signal transduction
04014 Ras signaling pathway
5338 (PLD2)
04072 Phospholipase D signaling pathway
5338 (PLD2)
04071 Sphingolipid signaling pathway
5338 (PLD2)
04024 cAMP signaling pathway
5338 (PLD2)
Cellular Processes
Transport and catabolism
04144 Endocytosis
5338 (PLD2)
Organismal Systems
Immune system
04666 Fc gamma R-mediated phagocytosis
5338 (PLD2)
Endocrine system
04912 GnRH signaling pathway
5338 (PLD2)
Nervous system
04724 Glutamatergic synapse
5338 (PLD2)
Human Diseases
Cancers
05231 Choline metabolism in cancer
5338 (PLD2)
Enzymes [BR:hsa01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.4 phospholipase D
5338 (PLD2)
Membrane trafficking [BR:hsa04131]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
5338 (PLD2)
Endosome - Golgi transport
Others
Others
5338 (PLD2)
 |
|---|
| SSDB |
   |
|---|
| Motif |
 |
|---|
| Other DBs |
NCBI-GeneID: NCBI-ProteinID: OMIM: HGNC: Ensembl: Vega: Pharos: UniProt: |
|---|
| Position |
17p13.2
|
|---|
| AA seq |
933 aa  
MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFA
PGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVL
MSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYR
NYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVV
KDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQAR
WWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIF
ITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRAL
MLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSE
SAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPW
RDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQ
CTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDE
IVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHR
LKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLL
GKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICD
DFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQ
GHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT |
|---|
| NT seq |
2802 nt  +upstreamnt +downstreamnt
atgacggcgacccctgagagcctcttccccactggggacgaactggactccagccagctc
cagatggagtccgatgaggtggacaccctgaaggagggagaggacccagccgaccggatg
cacccgtttctggccatctatgagcttcagtctctgaaagtgcaccccttggtgttcgca
cctggggtccctgtcacagcccaggtggtgggcaccgaaagatataccagcggatccaag
gtgggaacctgcactctgtattctgtccgcttgactcacggcgacttttcctggacaacc
aagaagaaataccgtcattttcaggagctgcatcgggacctcctgagacacaaagtcttg
atgagtctgctccctctggctcgatttgccgttgcctattctccagcccgagatgcaggc
aacagagagatgccctctctaccccgggcaggtcctgagggctccaccagacatgcagcc
agcaaacagaaatacctggagaattacctcaaccgtctcttgaccatgtctttctatcgc
aactaccatgccatgacagagttcctggaagtcagtcagctgtcctttatcccggacttg
ggccgcaaaggactggaggggatgatccggaagcgctcaggtggccaccgtgttcctggc
ctcacctgctgtggccgagaccaagtttgttatcgctggtccaagaggtggctggtggtg
aaggactccttcctgctgtacatgtgcctcgagacaggtgccatctcatttgttcagctc
tttgaccctggctttgaggtgcaagtggggaaaaggagcacggaggcacggcacggcgtg
cggatcgatacctcccacaggtccttgattctcaagtgcagcagctaccggcaggcacgg
tggtgggcccaagagatcactgagctggcacagggcccaggcagagacttcctacagctg
caccggcatgacagctacgccccaccccggcctgggaccttggcccggtggtttgtgaat
ggggcaggttactttgctgctgtggcagatgccatccttcgagctcaagaggagattttc
atcacagactggtggttgagtcctgaggtttacctgaagcgtccggcccattcagatgac
tggagactggacattatgctcaagaggaaggcggaggagggtgtccgtgtgtctattctg
ctgtttaaagaagtggaattggccttgggcatcaacagtggctatagcaagagggcgctg
atgctgctgcaccccaacataaaggtgatgcgtcacccagaccaagtgacgttgtgggcc
catcatgagaagctcctggtggtggaccaagtggtagcattcctggggggactggacctt
gcctatggccgctgggatgacctgcactaccgactgactgaccttggagactcctctgaa
tcagctgcctcccagcctcccaccccgcgcccagactcaccagccaccccagacctctct
cacaaccaattcttctggctgggcaaggactacagcaatcttatcaccaaggactgggtg
cagctggaccggcctttcgaagatttcattgacagggagacgacccctcggatgccatgg
cgggacgttggggtggtcgtccatggcctaccggcccgggaccttgcccggcacttcatc
cagcgctggaacttcaccaagaccaccaaggccaagtacaagactcccacatacccctac
ctgcttcccaagtctaccagcacggccaatcagctccccttcacacttccaggagggcag
tgcaccaccgtacaggtcttgcgatcagtggaccgctggtcagcagggactctggagaac
tccatcctcaatgcctacctgcacaccatcagggagagccagcacttcctctacattgag
aatcagttcttcattagctgctcagatgggcggacggttctgaacaaggtgggcgatgag
attgtggacagaatcctgaaggcccacaaacaggggtggtgttaccgagtctacgtgctt
ttgcccttactccctggcttcgagggtgacatctccacgggcggtggcaactccatccag
gccattctgcactttacttacaggaccctgtgtcgtggggagtattcaatcctgcatcgc
cttaaagcagccatggggacagcatggcgggactatatttccatctgcgggcttcgtaca
cacggagagctgggcgggcaccccgtctcggagctcatctacatccacagcaaggtgctc
atcgcagatgaccggacagtcatcattggttctgcaaacatcaatgaccggagcttgctg
gggaagcgggacagtgagctggccgtgctgatcgaggacacagagacggaaccatccctc
atgaatggggcagagtatcaggcgggcaggtttgccttgagtctgcggaagcactgcttc
ggtgtgattcttggagcaaatacccggccagacttggatctccgagaccccatctgtgat
gacttcttccagttgtggcaagacatggctgagagcaacgccaatatctatgagcagatc
ttccgctgcctgccatccaatgccacgcgttccctgcggactctccgggagtacgtggcc
gtggagcccttggccacggtcagtccccccttggctcggtctgagctcacccaggtccag
ggccacctggtccacttccccctcaagttcctagaggatgagtctttgctgcccccgctg
ggtagcaaggagggcatgatccccctagaagtgtggacatag |
|---|
