KEGG   Homo sapiens (human): 5423Help
Entry
5423              CDS       T01001                                 

Gene name
POLB
Definition
polymerase (DNA directed), beta (EC:2.7.7.7)
Orthology
K02330  
DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
Organism
hsa  Homo sapiens (human)
Pathway
Base excision repair
HTLV-I infection
Viral carcinogenesis
Module
BER complex
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Genetic Information Processing
  Replication and repair
   03410 Base excision repair
    5423 (POLB)
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    5423 (POLB)
  Infectious diseases
   05166 HTLV-I infection
    5423 (POLB)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     5423 (POLB)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.-  
     5423 (POLB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 
4KLI 2FMP 4KLG 4KLM 4KLJ 4F5N 4KLL 4KLO 3OGU 4KLF 4F5P 4KLH 3JPQ 4KLD 3RH4 4GXI 4DOC 4KLE 4KLU 4KLS 4KLT 4LVS 4KLQ 4JWM 4GXK 4F5O 3TFR 3TFS 3RJG 3RJJ 3MBY 3JPO 3JPS 3ISB 3ISC 2FMS 1TV9 4M9G 4M9J 4DO9 4DOA 4DOB 3RH6 4M9L 3RJE 3RJK 3RH5 3JPP 3JPR 2PXI 2ISO 2I9G 1ZJM 3JPN 3JPT 3C2M 4GXJ 4F5R 3RJH 3GDX 2ISP 2FMQ 1BPY 4F5Q 4NLN 4M9N 4M2Y 3RJF 3RJI 4M47 4M9H 4JWN 3C2K 1BPX 4NM1 4NLK 3LK9 2P66 4NM2 3ISD 3C2L 1TVA 1BPZ 9ICX 9ICW 1ZJN 4NLZ 8ICK 1ZQI 9ICK 9ICV 8ICO 1MQ3 7ICV 7ICE 7ICI 7ICN 7ICS 7ICT 8ICC 8ICI 1ZQP 9ICL 8ICN 7ICH 7ICK 7ICQ 8ICF 1ZQF 8ICM 8ICR 9ICQ 9ICM 9ICO 9ICS 9ICU 8ICP 8ICS 9ICH 9ICY 7ICG 7ICM 7ICP 7ICR 1ZQN 8ICQ 9ICR 9ICN 9ICT 8ICA 8ICU 8ICX 9ICA 9ICF 9ICG 1MQ2 7ICF 7ICL 8ICB 1ZQG 1ZQH 8ICZ 9ICP 8ICL 8ICT 8ICY 9ICC 9ICI 9ICJ 8ICE 8ICJ 1ZQA 1ZQB 1ZQC 1ZQK 1ZQM 1ZQO 8ICV 9ICB 7ICO 7ICU 8ICG 8ICH 1ZQJ 1ZQL 1ZQQ 1ZQS 8ICW 9ICE 1ZQT 7ICJ 1ZQD 1ZQE 1ZQR
Thumbnails

Jmol
Position
8p11.2
AA seq 335 aa AA seqDB search
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
NT seq 1008 nt NT seq  +upstreamnt  +downstreamnt
atgagcaaacggaaggcgccgcaggagactctcaacgggggaatcaccgacatgctcaca
gaactcgcaaactttgagaagaacgtgagccaagctatccacaagtacaatgcttacaga
aaagcagcatctgttatagcaaaatacccacacaaaataaagagtggagctgaagctaag
aaattgcctggagtaggaacaaaaattgctgaaaagattgatgagtttttagcaactgga
aaattacgtaaactggaaaagattcggcaggatgatacgagttcatccatcaatttcctg
actcgagttagtggcattggtccatctgctgcaaggaagtttgtagatgaaggaattaaa
acactagaagatctcagaaaaaatgaagataaattgaaccatcatcagcgaattgggctg
aaatattttggggactttgaaaaaagaattcctcgtgaagagatgttacaaatgcaagat
attgtactaaatgaagttaaaaaagtggattctgaatacattgctacagtctgtggcagt
ttcagaagaggtgcagagtccagtggtgacatggatgttctcctgacccatcccagcttc
acttcagaatcaaccaaacagccaaaactgttacatcaggttgtggagcagttacaaaag
gttcattttatcacagataccctgtcaaagggtgagacaaagttcatgggtgtttgccag
cttcccagtaaaaatgatgaaaaagaatatccacacagaagaattgatatcaggttgata
cccaaagatcagtattactgtggtgttctctatttcactgggagtgatattttcaataag
aatatgagggctcatgccctagaaaagggtttcacaatcaatgagtacaccatccgtccc
ttgggagtcactggagttgcaggagaacccctgccagtggatagtgaaaaagacatcttt
gattacatccagtggaaataccgggaacccaaggaccggagcgaatga

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