KEGG   Homo sapiens (human): 54578Help
Entry
54578             CDS       T01001                                 

Gene name
UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F
Definition
UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)
Orthology
K00699  
glucuronosyltransferase [EC:2.4.1.17]
Organism
hsa  Homo sapiens (human)
Pathway
Pentose and glucuronate interconversions
Ascorbate and aldarate metabolism
Steroid hormone biosynthesis
Starch and sucrose metabolism
Retinol metabolism
Porphyrin and chlorophyll metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Metabolic pathways
Chemical carcinogenesis
Module
Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    54578 (UGT1A6)
   00053 Ascorbate and aldarate metabolism
    54578 (UGT1A6)
   00500 Starch and sucrose metabolism
    54578 (UGT1A6)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    54578 (UGT1A6)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    54578 (UGT1A6)
   00860 Porphyrin and chlorophyll metabolism
    54578 (UGT1A6)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    54578 (UGT1A6)
   00982 Drug metabolism - cytochrome P450
    54578 (UGT1A6)
   00983 Drug metabolism - other enzymes
    54578 (UGT1A6)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    54578 (UGT1A6)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     54578 (UGT1A6)
Glycosyltransferases [BR:hsa01003]
 Others
  Hydrophobic molecule
   54578 (UGT1A6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
2q37
AA seq 532 aa AA seqDB search
MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVV
PEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIG
LYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEH
TFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRD
VDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHG
IVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLL
GHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSE
DLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDL
TWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
NT seq 1599 nt NT seq  +upstreamnt  +downstreamnt
atggcctgcctccttcgctcatttcagagaatttctgcaggggttttcttcttagcactt
tggggcatggttgtaggtgacaagctgctggtggtccctcaggacggaagccactggctt
agtatgaaggatatagttgaggttctcagtgaccggggtcatgagattgtagtggtggtg
cctgaagttaatttgcttttgaaagaatccaaatactacacaagaaaaatctatccagtg
ccgtatgaccaagaagagctgaagaaccgttaccaatcatttggaaacaatcactttgct
gagcgatcattcctaactgctcctcagacagagtacaggaataacatgattgttattggc
ctgtacttcatcaactgccagagcctcctgcaggacagggacaccctgaacttctttaag
gagagcaagtttgatgctcttttcacagacccagccttaccctgtggggtgatcctggct
gagtatttgggcctaccatctgtgtacctcttcaggggttttccgtgttccctggagcat
acattcagcagaagcccagaccctgtgtcctacattcccaggtgctacacaaagttttca
gaccacatgactttttcccaacgagtggccaacttccttgttaatttgttggagccctat
ctattttattgtctgttttcaaagtatgaagaactcgcatcagctgtcctcaagagagat
gtggatataatcaccttatatcagaaggtctctgtttggctgttaagatatgactttgtg
cttgaatatcctaggccggtcatgcccaacatggtcttcattggaggtatcaactgtaag
aagaggaaagacttgtctcaggaatttgaagcctacattaatgcttctggagaacatgga
attgtggttttctctttgggatcaatggtctcagaaattccagagaagaaagctatggca
attgctgatgctttgggcaaaatccctcagacagtcctgtggcggtacactggaacccga
ccatcgaatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgatctgctt
ggtcacccgatgacccgtgcctttatcacccatgctggttcccatggtgtttatgaaagc
atatgcaatggcgttcccatggtgatgatgcccttgtttggtgatcagatggacaatgca
aagcgcatggagactaagggagctggagtgaccctgaatgttctggaaatgacttctgaa
gatttagaaaatgctctaaaagcagtcatcaatgacaaaagttacaaggagaacatcatg
cgcctctccagccttcacaaggaccgcccggtggagccgctggacctggccgtgttctgg
gtggagtttgtgatgaggcacaagggcgcgccacacctgcgccccgcagcccacgacctc
acctggtaccagtaccattccttggacgtgattggtttcctcttggccgtcgtgctgaca
gtggccttcatcacctttaaatgttgtgcttatggctaccggaaatgcttggggaaaaaa
gggcgagttaagaaagcccacaaatccaagacccattga

DBGET integrated database retrieval system