KEGG   Homo sapiens (human): 54579Help
Entry
54579             CDS       T01001                                 

Gene name
UGT1A5, UDPGT, UDPGT_1-5, UGT1E
Definition
UDP glucuronosyltransferase 1 family, polypeptide A5 (EC:2.4.1.17)
Orthology
K00699  
glucuronosyltransferase [EC:2.4.1.17]
Organism
hsa  Homo sapiens (human)
Pathway
Pentose and glucuronate interconversions
Ascorbate and aldarate metabolism
Steroid hormone biosynthesis
Starch and sucrose metabolism
Retinol metabolism
Porphyrin and chlorophyll metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Metabolic pathways
Chemical carcinogenesis
Module
Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    54579 (UGT1A5)
   00053 Ascorbate and aldarate metabolism
    54579 (UGT1A5)
   00500 Starch and sucrose metabolism
    54579 (UGT1A5)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    54579 (UGT1A5)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    54579 (UGT1A5)
   00860 Porphyrin and chlorophyll metabolism
    54579 (UGT1A5)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    54579 (UGT1A5)
   00982 Drug metabolism - cytochrome P450
    54579 (UGT1A5)
   00983 Drug metabolism - other enzymes
    54579 (UGT1A5)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    54579 (UGT1A5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     54579 (UGT1A5)
Glycosyltransferases [BR:hsa01003]
 Others
  Hydrophobic molecule
   54579 (UGT1A5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
2q37
AA seq 534 aa AA seqDB search
MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV
LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM
SLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDL
DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
NT seq 1605 nt NT seq  +upstreamnt  +downstreamnt
atggccacaggactccaggttcccctgccgcagctggccacaggactgctgcttctcctc
agtgtccagccctgggctgagagtgggaaggtgctggtggtgcccactgatggcagccac
tggctcagcatgcgggaggccttgcgggacctccatgcgagaggccaccaggtggtggtc
ctcaccctggaggtgaatatgtacatcaaagaagagaactttttcaccctgacaacgtat
gccatttcatggacccaggacgaatttgatcgccttttgctgggtcacactcaatcgttc
tttgaaacagaacatcttctgatgaaattttctagaagaatggcaattatgaacaatatg
tctttgatcatacataggtcttgtgtggagctactgcataatgaggccctgatcaggcac
ctgcatgctacttcctttgatgtggttctaacagacccctttcacctctgcgcggcggtg
ctggctaagtacctgtcgattcctgctgtgtttttcttgaggaacattccatgtgattta
gactttaagggcacacagtgtccaaacccttcctcctatattcctagattactaacgacc
aattcagaccacatgacattcctgcaaagggtcaagaacatgctctaccctctggccctg
tcctacctttgccatgctgtttctgctccttatgcaagccttgcctctgagctttttcag
agagaggtgtcagtggtggatcttgtcagccatgcatctgtgtggctgttccgaggggac
tttgtgatggattaccccaggccgatcatgcccaacatggtcttcattgggggcatcaac
tgtgccaacgggaagccactatctcaggaatttgaagcctacattaatgcttctggagaa
catggaattgtggttttctctttgggatcaatggtctcagaaattccagagaagaaagct
atggcaattgctgatgctttgggcaaaatccctcagacagtcctgtggcggtacactgga
acccgaccatcgaatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgat
ctgcttggtcacccgatgacccgtgcctttatcacccatgctggttcccatggtgtttat
gaaagcatatgcaatggcgttcccatggtgatgatgcccttgtttggtgatcagatggac
aatgcaaagcgcatggagactaagggagctggagtgaccctgaatgttctggaaatgact
tctgaagatttagaaaatgctctaaaagcagtcatcaatgacaaaagttacaaggagaac
atcatgcgcctctccagccttcacaaggaccgcccggtggagccgctggacctggccgtg
ttctgggtggagtttgtgatgaggcacaagggcgcgccacacctgcgccccgcagcccac
gacctcacctggtaccagtaccattccttggacgtgattggtttcctcttggccgtcgtg
ctgacagtggccttcatcacctttaaatgttgtgcttatggctaccggaaatgcttgggg
aaaaaagggcgagttaagaaagcccacaaatccaagacccattga

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