KEGG   Homo sapiens (human): 54659Help
Entry
54659             CDS       T01001                                 

Gene name
UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1A3S, UGT1C
Definition
(RefSeq) UDP glucuronosyltransferase family 1 member A3
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00040  Pentose and glucuronate interconversions
hsa00053  Ascorbate and aldarate metabolism
hsa00140  Steroid hormone biosynthesis
hsa00830  Retinol metabolism
hsa00860  Porphyrin and chlorophyll metabolism
hsa00980  Metabolism of xenobiotics by cytochrome P450
hsa00982  Drug metabolism - cytochrome P450
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa05204  Chemical carcinogenesis
Module
hsa_M00014  Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    54659 (UGT1A3)
   00053 Ascorbate and aldarate metabolism
    54659 (UGT1A3)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    54659 (UGT1A3)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    54659 (UGT1A3)
   00860 Porphyrin and chlorophyll metabolism
    54659 (UGT1A3)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    54659 (UGT1A3)
   00982 Drug metabolism - cytochrome P450
    54659 (UGT1A3)
   00983 Drug metabolism - other enzymes
    54659 (UGT1A3)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    54659 (UGT1A3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     54659 (UGT1A3)
Glycosyltransferases [BR:hsa01003]
 Others
  Hydrophobic molecule
   54659 (UGT1A3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: UDPGT Glyco_tran_28_C Glyco_transf_4
Motif
Other DBs
NCBI-GeneID: 54659
NCBI-ProteinID: NP_061966
OMIM: 606428
HGNC: 12535
Ensembl: ENSG00000243135
Vega: OTTHUMG00000059118
Pharos: P35503(Tbio)
UniProt: P35503 Q5DT01
Position
2q37.1
AA seq 534 aa AA seqDB search
MATGLQVPLPWLATGLLLLLSVQPWAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVV
LTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNM
SLVYHRSCVELLHNEALIRHLNATSFDVVLTDPVNLCAAVLAKYLSIPTVFFLRNIPCDL
DFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYASLASELFQ
REVSVVDILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGE
HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
NT seq 1605 nt NT seq  +upstreamnt  +downstreamnt
atggccacaggactccaggttcccctgccgtggctggccacaggactgctgcttctcctc
agtgtccagccctgggctgagagtggaaaggtgttggtggtgcccattgatggcagccac
tggctcagcatgcgggaggtcttgcgggagctccatgccagaggccaccaggcagtggtc
ctcaccccagaggtgaatatgcacatcaaagaagagaactttttcaccctgacaacctat
gccatttcgtggacccaggatgaatttgatcgccatgtgctgggccacactcaactgtac
tttgaaacagaacattttctgaagaaatttttcagaagtatggcaatgttgaacaatatg
tctttggtctatcataggtcttgtgtggagctactacataatgaggccctgatcaggcac
ctgaatgctacttcctttgatgtggttttaacagaccccgttaacctctgcgcggcagtg
ctggctaagtacctgtcgattcctactgtgttttttttgaggaacattccatgtgattta
gactttaagggcacacagtgtccaaacccttcctcctatattcctagattactaacaacc
aattcagaccacatgacattcatgcaaagggtcaagaacatgctctaccctctggccctg
tcctacatttgccatgctttttctgctccttatgcaagccttgcctctgagctttttcag
agagaggtgtcagtggtggatattctcagtcatgcatctgtgtggctgttccgaggggac
tttgtgatggactaccccaggccaatcatgcccaacatggtcttcattgggggcatcaac
tgtgccaacaggaagccactatctcaggaatttgaagcctacattaatgcttctggagaa
catggaattgtggttttctctttgggatcaatggtctcagaaattccagagaagaaagct
atggcaattgctgatgctttgggcaaaatccctcagacagtcctgtggcggtacactgga
acccgaccatcgaatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgat
ctgcttggtcacccgatgacccgtgcctttatcacccatgctggttcccatggtgtttat
gaaagcatatgcaatggcgttcccatggtgatgatgcccttgtttggtgatcagatggac
aatgcaaagcgcatggagactaagggagctggagtgaccctgaatgttctggaaatgact
tctgaagatttagaaaatgctctaaaagcagtcatcaatgacaaaagttacaaggagaac
atcatgcgcctctccagccttcacaaggaccgcccggtggagccgctggacctggccgtg
ttctgggtggagtttgtgatgaggcacaagggcgcgccacacctgcgccccgcagcccac
gacctcacctggtaccagtaccattccttggacgtgattggtttcctcttggccgtcgtg
ctgacagtggccttcatcacctttaaatgttgtgcttatggctaccggaaatgcttgggg
aaaaaagggcgagttaagaaagcccacaaatccaagacccattga

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