KEGG   Homo sapiens (human): 55879Help
Entry
55879             CDS       T01001                                 

Gene name
GABRQ, THETA
Definition
gamma-aminobutyric acid (GABA) A receptor, theta
Orthology
K05192  
gamma-aminobutyric acid receptor subunit theta
Organism
hsa  Homo sapiens (human)
Pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Drug target
Hexobarbital: 
Thiopental: 
Propofol: 
Methylphenobarbital: 
Phenobarbital: 
Clonazepam: 
Aminobutyric acid: 
Diazepam: 
Chlordiazepoxide: 
Medazepam: 
Oxazepam: 
Potassium clorazepate: 
Lorazepam: 
Adinazolam: 
Bromazepam: 
Clobazam: 
Prazepam: 
Alprazolam: 
Nordazepam: 
Fludiazepam: 
Ethyl loflazepate: 
Etizolam: 
Clotiazepam: 
Cloxazolam: 
Tofisopam: 
Meprobamate: 
Pentobarbital: 
Amobarbital: 
Barbital: 
Secobarbital: 
Flurazepam: 
Nitrazepam: 
Flunitrazepam: 
Estazolam: 
Triazolam: 
Lormetazepam: 
Temazepam: 
Midazolam: 
Brotizolam: 
Quazepam: 
Loprazolam: 
Glutethimide: 
Zopiclone: 
Zolpidem: 
Eszopiclone: 
Methaqualone: 
Pentetrazol: 
Flumazenil: 
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    55879 (GABRQ)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    55879 (GABRQ)
   04723 Retrograde endocannabinoid signaling
    55879 (GABRQ)
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    55879 (GABRQ)
   05033 Nicotine addiction
    55879 (GABRQ)
Ion channels [BR:hsa04040]
 Cys-loop superfamily
  GABA-A
   55879 (GABRQ)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
UniProt: 
Position
Xq28
AA seq 632 aa AA seqDB search
MGIRGMLRAAVILLLIRTWLAEGNYPSPIPKFHFEFSSAVPEVVLNLFNCKNCANEAVVQ
KILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLA
YYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTT
AACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTI
TSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTI
GLTSMLILTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRR
QPRRHRRPRRVIARYRYQQVVVGNVQDGLINVEDGVSSLPITPAQAPLASPESLGSLTST
SEQAQLATSESLSPLTSLSGQAPLATGESLSDLPSTSEQARHSYGVRFNGFQADDSIIPT
EIRNRVEAHGHGVTHDHEDSNESLSSDERHGHGPSGKPMLHHGEKGVQEAGWDLDDNNDK
SDCLAIKEQFKCDTNSTWGLNDDELMAHGQEKDSSSESEDSCPPSPGCSFTEGFSFDLFN
PDYVPKVDKWSRFLFPLAFGLFNIVYWVYHMY
NT seq 1899 nt NT seq  +upstreamnt  +downstreamnt
atgggcatccgaggcatgctgcgagccgcagtgatcctgctgctcatcaggacctggctc
gcggagggcaactaccccagtcccatcccgaaattccacttcgagttctcctctgctgtg
cccgaagtcgtcctgaacctcttcaactgcaaaaattgtgcaaatgaagctgtggttcaa
aagattttggacagggtgctgtcaagatacgatgtccgcctgagaccgaattttggaggt
gcccctgtgcctgtgagaatatctatttatgtcacgagcattgaacagatctcagaaatg
aatatggactacacgatcacgatgttttttcatcagacttggaaagattcacgcttagca
tactatgagaccaccctgaacttgaccctggactatcggatgcatgagaagttgtgggtc
cctgactgctactttctgaacagcaaggatgctttcgtgcatgatgtgactgtggagaat
cgcgtgtttcagcttcacccagatggaacggtgcggtacggcatccgactcaccactaca
gcagcttgttccctggatctgcataaattccctatggacaagcaggcctgcaacctggtg
gtagagagctatggttacacggttgaagacatcatattattctgggatgacaatgggaac
gccatccacatgactgaggagctgcatatccctcagttcactttcctgggaaggacgatt
actagcaaggaggtgtatttctacacaggttcctacatacgcctgatactgaagttccag
gttcagagggaagttaacagctaccttgtgcaagtctactggcctactgtcctcaccact
attacctcttggatatcgttttggatgaactatgattcctctgcagccagggtgacaatt
ggcttaacttcaatgctcatcctgaccaccatcgactcacatctgcgggataagctcccc
aacatttcctgtatcaaggccattgatatctatatcctcgtgtgcttgttctttgtgttc
ctgtccttgctggagtatgtctacatcaactatcttttctacagtcgaggacctcggcgc
cagcctaggcgacacaggagaccccgaagagtcattgcccgctaccgctaccagcaagtg
gtggtaggaaacgtgcaggatggcctgattaacgtggaagacggagtcagctctctcccc
atcaccccagcgcaggcccccctggcaagcccggaaagcctcggttctttgacgtccacc
tccgagcaggcccagctggccacctcggaaagcctcagcccactcacttctctctcaggc
caggcccccctggccactggagaaagcctgagcgatctcccctccacctcagagcaggcc
cggcacagctatggtgttcgctttaatggtttccaggctgatgacagtattattcctacc
gaaatccgcaaccgtgtcgaagcccatggccatggtgttacccatgaccatgaagattcc
aatgagagcttgagctcggatgagcgccatggccatggccccagtgggaagcccatgctt
caccatggcgagaagggtgtgcaagaagcaggctgggaccttgatgacaacaatgacaag
agcgactgccttgccattaaggagcaattcaagtgtgatactaacagtacctggggcctt
aatgatgatgagctcatggcccatggccaagagaaggacagtagctcagagtctgaggat
agttgccccccaagccctgggtgctccttcactgaagggttctccttcgatctctttaat
cctgactacgtcccaaaggtcgacaagtggtcccggttcctcttccctctggcctttggg
ttgttcaacattgtttactgggtataccatatgtattag

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