KEGG T01001: 5607

Homo sapiens (human): 5607

Entry

5607 CDS T01001

Gene name

MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5

Definition

mitogen-activated protein kinase kinase 5 (EC:2.7.12.2)

Orthology

K04463

mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]

Organism

hsa Homo sapiens (human)

Pathway

hsa04010	MAPK signaling pathway
hsa04540	Gap junction
hsa04722	Neurotrophin signaling pathway

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:hsa04010]
Cellular Processes; Cell communication; Gap junction [PATH:hsa04540]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:hsa04722]

SSDB

Motif

Pfam:

Pkinase Pkinase_Tyr PB1 Kinase-like Seadorna_VP7 APH

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2NPT 2O2V 4IC7

Position

15q23

AA seq 412 aa
MMEGHFPQSDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNG
QLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKIL
ANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEIL
YKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWS
LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIH
SDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFI
TQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP

NT seq 1239 nt +upstreamnt +downstreamnt
atgatggagggtcactttccccagagcgatgtgataggccaggttctgcctgaagcaaca
actacagcatttgaatatgaagatgaagatggtgatcgaattacagtgagaagtgatgag
gaaatgaaggcaatgctgtcatattattattccacagtaatggaacagcaagtaaatgga
cagttaatagagcctctgcagatatttccaagagcctgcaagcctcctggggaacggaac
atacatggcctgaaggtgaatactcgggccggaccctctcaacacagcagcccagcagtc
tcagattcacttccaagcaatagcttaaagaagtcttctgctgaactgaaaaaaatacta
gccaatggccagatgaatgaacaagacatacgatatcgggacactcttggtcatggcaac
ggaggcacagtctacaaagcatatcatgtcccgagtgggaaaatattagctgtaaaggtc
atactactagatattacactggaacttcagaagcaaattatgtctgaattggaaattctt
tataagtgcgattcatcatatatcattggattttatggagcattttttgtagaaaacagg
atttcaatatgtacagaattcatggatgggggatctttggatgtatataggaaaatgcca
gaacatgtccttggaagaattgcagtagcagttgttaaaggccttacttatttgtggagt
ttaaagattttacatagagacgtgaagccctccaatatgctagtaaacacaagaggacag
gttaagctgtgtgattttggagttagcactcagctggtgaattctatagccaagacgtat
gttggaacaaatgcttatatggcgcctgaaaggatttcaggggagcagtatggaattcat
tctgatgtctggagcttaggaatctcttttatggagcttgctcttgggaggtttccatat
cctcagattcagaaaaaccagggatctttaatgcctctccagcttctgcagtgcattgtt
gatgaggattcgcccgtccttccagttggagagttctcggagccatttgtacatttcatc
actcagtgtatgcgaaaacagccaaaagaaaggccagcacctgaagaattgatgggccac
ccgttcatcgtgcagttcaatgatggaaatgccgccgtggtgtccatgtgggtgtgccgg
gcgctggaggagaggcggagccagcaggggcccccgtga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (10)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (31)   
   RefSeq(nuc) (5)   
   GenBank (13)   
   EMBL (13)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (68)   

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