KEGG   Homo sapiens (human): 5607Help
Entry
5607              CDS       T01001                                 

Gene name
MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5
Definition
mitogen-activated protein kinase kinase 5 (EC:2.7.12.2)
Orthology
K04463  
mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Gap junction
Neurotrophin signaling pathway
Oxytocin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    5607 (MAP2K5)
 Cellular Processes
  Cellular commiunity
   04540 Gap junction
    5607 (MAP2K5)
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    5607 (MAP2K5)
  Nervous system
   04722 Neurotrophin signaling pathway
    5607 (MAP2K5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     5607 (MAP2K5)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   5607 (MAP2K5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
15q23
AA seq 412 aa AA seqDB search
MMEGHFPQSDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNG
QLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKIL
ANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEIL
YKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWS
LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIH
SDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFI
TQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP
NT seq 1239 nt NT seq  +upstreamnt  +downstreamnt
atgatggagggtcactttccccagagcgatgtgataggccaggttctgcctgaagcaaca
actacagcatttgaatatgaagatgaagatggtgatcgaattacagtgagaagtgatgag
gaaatgaaggcaatgctgtcatattattattccacagtaatggaacagcaagtaaatgga
cagttaatagagcctctgcagatatttccaagagcctgcaagcctcctggggaacggaac
atacatggcctgaaggtgaatactcgggccggaccctctcaacacagcagcccagcagtc
tcagattcacttccaagcaatagcttaaagaagtcttctgctgaactgaaaaaaatacta
gccaatggccagatgaatgaacaagacatacgatatcgggacactcttggtcatggcaac
ggaggcacagtctacaaagcatatcatgtcccgagtgggaaaatattagctgtaaaggtc
atactactagatattacactggaacttcagaagcaaattatgtctgaattggaaattctt
tataagtgcgattcatcatatatcattggattttatggagcattttttgtagaaaacagg
atttcaatatgtacagaattcatggatgggggatctttggatgtatataggaaaatgcca
gaacatgtccttggaagaattgcagtagcagttgttaaaggccttacttatttgtggagt
ttaaagattttacatagagacgtgaagccctccaatatgctagtaaacacaagaggacag
gttaagctgtgtgattttggagttagcactcagctggtgaattctatagccaagacgtat
gttggaacaaatgcttatatggcgcctgaaaggatttcaggggagcagtatggaattcat
tctgatgtctggagcttaggaatctcttttatggagcttgctcttgggaggtttccatat
cctcagattcagaaaaaccagggatctttaatgcctctccagcttctgcagtgcattgtt
gatgaggattcgcccgtccttccagttggagagttctcggagccatttgtacatttcatc
actcagtgtatgcgaaaacagccaaaagaaaggccagcacctgaagaattgatgggccac
ccgttcatcgtgcagttcaatgatggaaatgccgccgtggtgtccatgtgggtgtgccgg
gcgctggaggagaggcggagccagcaggggcccccgtga

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