KEGG   Homo sapiens (human): 56848Help
Entry
56848             CDS       T01001                                 

Gene name
SPHK2, SK_2, SK-2, SPK_2, SPK-2
Definition
sphingosine kinase 2 (EC:2.7.1.91)
Orthology
K04718  
sphingosine kinase [EC:2.7.1.91]
Organism
hsa  Homo sapiens (human)
Pathway
Sphingolipid metabolism
Metabolic pathways
Calcium signaling pathway
VEGF signaling pathway
Fc gamma R-mediated phagocytosis
Tuberculosis
Module
Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    56848 (SPHK2)
 Environmental Information Processing
  Signal transduction
   04370 VEGF signaling pathway
    56848 (SPHK2)
   04020 Calcium signaling pathway
    56848 (SPHK2)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    56848 (SPHK2)
 Human Diseases
  Infectious diseases
   05152 Tuberculosis
    56848 (SPHK2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphinganine kinase
     56848 (SPHK2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
19q13.2
AA seq 595 aa AA seqDB search
MNGHLEAEEQQDQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYT
YPRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPR
PPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWD
GIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLD
LLLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFT
LGTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRS
VSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPK
AALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPPDWVTLEGDFV
LMLAISPSHLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQ
LGYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGIGTLLTGPPGCPGREP
NT seq 1788 nt NT seq  +upstreamnt  +downstreamnt
atgaatggacaccttgaagcagaggagcagcaggaccaggccctgcacatacagcggctg
cgccccaaacctgaagccaggccccggggtggcctggtcccgttggccgaggtctcaggc
tgctgcaccctgcgaagccgcagcccctcagactcagcggcctacttctgcatctacacc
taccctcggggccggcgcggggcccggcgcagagccactcgcaccttccgggcagatggg
gccgccacctacgaagagaaccgtgccgaggcccagcgctgggccactgccctcacctgt
ctgctccgaggactgccactgcccggggatggggagatcacccctgacctgctacctcgg
ccgccccggttgcttctattggtcaatccctttgggggtcggggcctggcctggcagtgg
tgtaagaaccacgtgcttcccatgatctctgaagctgggctgtccttcaacctcatccag
acagaacgacagaaccacgcccgggagctggtccaggggctgagcctgagtgagtgggat
ggcatcgtcacggtctcgggagacgggctgctccatgaggtgctgaacgggctcctagat
cgccctgactgggaggaagctgtgaagatgcctgtgggcatcctcccctgcggctcgggc
aacgcgctggccggagcagtgaaccagcacgggggatttgagccagccctgggcctcgac
ctgttgctcaactgctcactgttgctgtgccggggtggtggccacccactggacctgctc
tccgtgacgctggcctcgggctcccgctgtttctccttcctgtctgtggcctggggcttc
gtgtcagatgtggatatccagagcgagcgcttcagggccttgggcagtgcccgcttcaca
ctgggcacggtgctgggcctcgccacactgcacacctaccgcggacgcctctcctacctc
cccgccactgtggaacctgcctcgcccacccctgcccatagcctgcctcgtgccaagtcg
gagctgaccctaaccccagacccagccccgcccatggcccactcacccctgcatcgttct
gtgtctgacctgcctcttcccctgccccagcctgccctggcctctcctggctcgccagaa
cccctgcccatcctgtccctcaacggtgggggcccagagctggctggggactggggtggg
gctggggatgctccgctgtccccggacccactgctgtcttcacctcctggctctcccaag
gcagctctacactcacccgtctccgaaggggcccccgtaattcccccatcctctgggctc
ccacttcccacccctgatgcccgggtaggggcctccacctgcggcccgcccgaccacctg
ctgcctccgctgggcaccccgctgcccccagactgggtgacgctggagggggactttgtg
ctcatgttggccatctcgcccagccacctaggcgctgacctggtggcagctccgcatgcg
cgcttcgacgacggcctggtgcacctgtgctgggtgcgtagcggcatctcgcgggctgcg
ctgctgcgccttttcttggccatggagcgtggtagccacttcagcctgggctgtccgcag
ctgggctacgccgcggcccgtgccttccgcctagagccgctcacaccacgcggcgtgctc
acagtggacggggagcaggtggagtatgggccgctacaggcacagatgcaccctggcatc
ggtacactgctcactgggcctcctggctgcccggggcgggagccctga

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