KEGG   Homo sapiens (human): 5770Help
Entry
5770              CDS       T01001                                 

Gene name
PTPN1, PTP1B
Definition
(RefSeq) protein tyrosine phosphatase, non-receptor type 1 (EC:3.1.3.48)
  KO
K05696  
tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
Adherens junction
Insulin signaling pathway
Insulin resistance
Drug target
Other: 
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Cellular commiunity
   04520 Adherens junction
    5770 (PTPN1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    5770 (PTPN1)
 Human Diseases
  Endocrine and metabolic diseases
   04931 Insulin resistance
    5770 (PTPN1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     5770 (PTPN1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    5770 (PTPN1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
20q13.1-q13.2
AA seq 362 aa AA seqDB search
MEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEM
IFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLN
FLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEM
RKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPP
KRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSR
VVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFNS
NT
NT seq 1089 nt NT seq  +upstreamnt  +downstreamnt
atggaagaagcccaaaggagttacattcttacccagggccctttgcctaacacatgcggt
cacttttgggagatggtgtgggagcagaaaagcaggggtgtcgtcatgctcaacagagtg
atggagaaaggttcgttaaaatgcgcacaatactggccacaaaaagaagaaaaagagatg
atctttgaagacacaaatttgaaattaacattgatctctgaagatatcaagtcatattat
acagtgcgacagctagaattggaaaaccttacaacccaagaaactcgagagatcttacat
ttccactataccacatggcctgactttggagtccctgaatcaccagcctcattcttgaac
tttcttttcaaagtccgagagtcagggtcactcagcccggagcacgggcccgttgtggtg
cactgcagtgcaggcatcggcaggtctggaaccttctgtctggctgatacctgcctcttg
ctgatggacaagaggaaagacccttcttccgttgatatcaagaaagtgctgttagaaatg
aggaagtttcggatggggctgatccagacagccgaccagctgcgcttctcctacctggct
gtgatcgaaggtgccaaattcatcatgggggactcttccgtgcaggatcagtggaaggag
ctttcccacgaggacctggagcccccacccgagcatatccccccacctccccggccaccc
aaacgaatcctggagccacacaatgggaaatgcagggagttcttcccaaatcaccagtgg
gtgaaggaagagacccaggaggataaagactgccccatcaaggaagaaaaaggaagcccc
ttaaatgccgcaccctacggcatcgaaagcatgagtcaagacactgaagttagaagtcgg
gtcgtggggggaagtcttcgaggtgcccaggctgcctccccagccaaaggggagccgtca
ctgcccgagaaggacgaggaccatgcactgagttactggaagcccttcctggtcaacatg
tgcgtggctacggtcctcacggccggcgcttacctctgctacaggttcctgttcaacagc
aacacatag

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