KEGG T01001: 5792

Homo sapiens (human): 5792

Entry

5792 CDS T01001

Gene name

PTPRF, LAR

Definition

protein tyrosine phosphatase, receptor type, F (EC:3.1.3.48)

Orthology

K05695

receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]

Organism

hsa Homo sapiens (human)

Pathway

hsa04514	Cell adhesion molecules (CAMs)
hsa04520	Adherens junction
hsa04910	Insulin signaling pathway

Class

Environmental Information Processing; Signaling molecules and interaction; Cell adhesion molecules (CAMs) [PATH:hsa04514]
Cellular Processes; Cell communication; Adherens junction [PATH:hsa04520]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:hsa04910]

SSDB

Motif

Pfam:

Y_phosphatase fn3 I-set Ig_2 Ig_3 Interfer-bind ig DSPc C2-set_2 V-set Y_phosphatase3 PTPlike_phytase TMEM154 ICAM_N

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1LAR 2YD8 2YD5 2EDX 2EDY 2DN7 2DJU

Position

1p34

AA seq 1907 aa
MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP
KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA
KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS
NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS
QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA
ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE
GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV
QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP
GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI
IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR
TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD
GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL
NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDY
ETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQW
HPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGL
GEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS
QQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRV
AAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNR
GSSAGGLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPID
RVGGSMLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTL
GDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPE
MLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLN
YQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNR
YANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWE
QRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGS
SEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIV
IDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNL
YAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTR
VCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTK
LREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQF
TDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMR
YEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT

NT seq 5724 nt +upstreamnt +downstreamnt
atggcccctgagccagccccagggaggacgatggtgccccttgtgcctgcactggtgatg
cttggtttggtggcaggcgcccatggtgacagcaaacctgtcttcattaaagtccctgag
gaccagactgggctgtcaggaggggtagcctccttcgtgtgccaagctacaggagaaccc
aagccgcgcatcacatggatgaagaaggggaagaaagtcagctcccagcgcttcgaggtc
attgagtttgatgatggggcagggtcagtgcttcggatccagccattgcgggtgcagcga
gatgaagccatctatgagtgtacagctactaacagcctgggtgagatcaacactagtgcc
aagctctcagtgctcgaagaggaacagctgccccctgggttcccttccatcgacatgggg
cctcagctgaaggtggtggagaaggcacgcacagccaccatgctatgtgccgcaggcgga
aatccagaccctgagatttcttggttcaaggacttccttcctgtagaccctgccacgagc
aacggccgcatcaagcagctgcgttcaggtgccttgcagatagagagcagtgaggaatcc
gaccaaggcaagtacgagtgtgtggcgaccaactcggcaggcacacgttactcagcccct
gcgaacctgtatgtgcgagtgcgccgcgtggctcctcgtttctccatccctcccagcagc
caggaggtgatgccaggcggcagcgtgaacctgacatgcgtggcagtgggtgcacccatg
ccctacgtgaagtggatgatgggggccgaggagctcaccaaggaggatgagatgccagtt
ggccgcaacgtcctggagctcagcaatgtcgtacgctctgccaactacacctgtgtggcc
atctcctcgctgggcatgatcgaggccacagcccaggtcacagtgaaagctcttccaaag
cctccgattgatcttgtggtgacagagacaactgccaccagtgtcaccctcacctgggac
tctgggaactcggagcctgtaacctactatggcatccagtaccgcgcagcgggcacggag
ggcccctttcaggaggtggatggtgtggccaccacccgctacagcattggcggcctcagc
cctttctcggaatatgccttccgcgtgctggcggtgaacagcatcgggcgagggccgccc
agcgaggcagtgcgggcacgcacgggagaacaggcgccctccagcccaccgcgccgcgtg
caggcacgcatgctgagcgccagcaccatgctggtgcagtgggagcctcccgaggagccc
aacggcctggtgcggggataccgcgtctactatactccggactcccgccgccccccgaac
gcctggcacaagcacaacaccgacgcggggctcctcacgaccgtgggcagcctgctgcct
ggcatcacctacagcctgcgcgtgcttgccttcaccgccgtgggcgatggccctcccagc
cccaccatccaggtcaagacgcagcagggagtgcctgcccagcccgcggacttccaggcc
gaggtggagtcggacaccaggatccagctctcgtggctgctgccccctcaggagcggatc
atcatgtatgaactggtgtactgggcggcagaggacgaagaccaacagcacaaggtgacc
ttcgacccaacctcctcctacacactagaggacctgaagcctgacacactctaccgcttc
cagctggctgcacgctcggatatgggggtgggcgtcttcacccccaccattgaggcccgc
acagcccagtccaccccctccgcccctccccagaaggtgatgtgtgtgagcatgggctcc
accacggtccgggtaagttgggtcccgccgcctgccgacagccgcaacggcgttatcacc
cagtactccgtggcctacgaggcggtggacggcgaggaccgcgggcggcatgtggtggat
ggcatcagccgtgagcactccagctgggacctggtgggcctggagaagtggacggagtac
cgggtgtgggtgcgggcacacacagacgtgggccccggccccgagagcagcccggtgctg
gtgcgcaccgatgaggacgtgcccagcgggcctccgcggaaggtggaggtggagccactg
aactccactgctgtgcatgtctactggaagctgcctgtccccagcaagcagcatggccag
atccgcggctaccaggtcacctacgtgcggctggagaatggcgagccccgtggactcccc
atcatccaagacgtcatgctagccgaggcccagtggcggccagaggagtccgaggactat
gaaaccactatcagcggcctgaccccggagaccacctactccgttactgttgctgcctat
accaccaagggggatggtgcccgcagcaagcccaaaattgtcactacaacaggtgcagtc
ccaggccggcccaccatgatgatcagcaccacggccatgaacactgcgctgctccagtgg
cacccacccaaggaactgcctggcgagctgctgggctaccggctgcagtactgccgggcc
gacgaggcgcggcccaacaccatagatttcggcaaggatgaccagcacttcacagtcacc
ggcctgcacaaggggaccacctacatcttccggcttgctgccaagaaccgggctggcttg
ggtgaggagttcgagaaggagatcaggacccccgaggacctgcccagcggcttcccccaa
aacctgcatgtgacaggactgaccacgtctaccacagaactggcctgggacccgccagtg
ctggcggagaggaacgggcgcatcatcagctacaccgtggtgttccgagacatcaacagc
caacaggagctgcagaacatcacgacagacacccgctttacccttactggcctcaagcca
gacaccacttacgacatcaaggtccgcgcatggaccagcaaaggctctggcccactcagc
cccagcatccagtcccggaccatgccggtggagcaagtgtttgccaagaacttccgggtg
gcggctgcaatgaagacgtctgtgctgctcagctgggaggttcccgactcctataagtca
gctgtgccctttaagattctgtacaatgggcagagtgtggaggtggacgggcactcgatg
cggaagctgatcgcagacctgcagcccaacacagagtactcgtttgtgctgatgaaccgt
ggcagcagcgcagggggcctgcagcacctggtgtccatccgcacagcccccgacctcctg
cctcacaagccgctgcctgcctctgcctacatagaggacggccgcttcgatctctccatg
ccccatgtgcaagacccctcgcttgtcaggtggttctacattgttgtggtgcccattgac
cgtgtgggcgggagcatgctgacgccaaggtggagcacacccgaggaactggagctggac
gagcttctagaagccatcgagcaaggcggagaggagcagcggcggcggcggcggcaggca
gaacgtctgaagccatatgtggctgctcaactggatgtgctcccggagacctttaccttg
ggggacaagaagaactaccggggcttctacaaccggcccctgtctccggacttgagctac
cagtgctttgtgcttgcctccttgaaggaacccatggaccagaagcgctatgcctccagc
ccctactcggatgagatcgtggtccaggtgacaccagcccagcagcaggaggagccggag
atgctgtgggtgacgggtcccgtgctggcagtcatcctcatcatcctcattgtcatcgcc
atcctcttgttcaaaaggaaaaggacccactctccgtcctctaaggatgagcagtcgatc
ggactgaaggactccttgctggcccactcctctgaccctgtggagatgcggaggctcaac
taccagaccccaggtatgcgagaccacccacccatccccatcaccgacctggcggacaac
atcgagcgcctcaaagccaacgatggcctcaagttctcccaggagtatgagtccatcgac
cctggacagcagttcacgtgggagaattcaaacctggaggtgaacaagcccaagaaccgc
tatgcgaatgtcatcgcctacgaccactctcgagtcatccttacctctatcgatggcgtc
cccgggagtgactacatcaatgccaactacatcgatggctaccgcaagcagaatgcctac
atcgccacgcagggccccctgcccgagaccatgggtgatttctggaggatggtgtgggaa
cagcgcacggccactgtggtcatgatgacacggctggaggagaagtcccgggtaaaatgt
gatcagtactggccagcccgtggcaccgagacctgtggccttattcaggtgaccctgttg
gacacagtggagctggccacatacactgtgcgcaccttcgcactccacaagagtggctcc
agtgagaagcgcgagctgcgtcagtttcagttcatggcctggccagaccatggagttcct
gagtacccaactcccatcctggccttcctacgacgggtcaaggcctgcaaccccctagac
gcagggcccatggtggtgcactgcagcgcgggcgtgggccgcaccggctgcttcatcgtg
attgatgccatgttggagcggatgaagcacgagaagacggtggacatctatggccacgtg
acctgcatgcgatcacagaggaactacatggtgcagacggaggaccagtacgtgttcatc
catgaggcgctgctggaggctgccacgtgcggccacacagaggtgcctgcccgcaacctg
tatgcccacatccagaagctgggccaagtgcctccaggggagagtgtgaccgccatggag
ctcgagttcaagttgctggccagctccaaggcccacacgtcccgcttcatcagcgccaac
ctgccctgcaacaagttcaagaaccggctggtgaacatcatgccctacgaattgacccgt
gtgtgtctgcagcccatccgtggtgtggagggctctgactacatcaatgccagcttcctg
gatggttatagacagcagaaggcctacatagctacacaggggcctctggcagagagcacc
gaggacttctggcgcatgctatgggagcacaattccaccatcatcgtcatgctgaccaag
cttcgggagatgggcagggagaaatgccaccagtactggccagcagagcgctctgctcgc
taccagtactttgttgttgacccgatggctgagtacaacatgccccagtatatcctgcgt
gagttcaaggtcacggatgcccgggatgggcagtcaaggacaatccggcagttccagttc
acagactggccagagcagggcgtgcccaagacaggcgagggattcattgacttcatcggg
caggtgcataagaccaaggagcagtttggacaggatgggcctatcacggtgcactgcagt
gctggcgtgggccgcaccggggtgttcatcactctgagcatcgtcctggagcgcatgcgc
tacgagggcgtggtcgacatgtttcagaccgtgaagaccctgcgtacacagcgtcctgcc
atggtgcagacagaggaccagtatcagctgtgctaccgtgcggccctggagtacctcggc
agctttgaccactatgcaacgtaa

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (13)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (36)   
   RefSeq(nuc) (2)   
   GenBank (17)   
   EMBL (17)   
3D Structure (7)   
   PDB (7)   
Protein domain (14)   
   Pfam (14)   
All databases (87)   

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