KEGG T01001: 590

Homo sapiens (human): 590

Entry

590 CDS T01001

Gene name

BCHE, CHE1, E1

Definition

butyrylcholinesterase (EC:3.1.1.8)

Orthology

K01050

cholinesterase [EC:3.1.1.8]

Organism

hsa Homo sapiens (human)

Drug target

Rivastigmine:

D03822

Fluostigmine:

D00043

Other:

D02729 D08094

Class

SSDB

Motif

Pfam:

COesterase AChE_tetra Abhydrolase_3

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2WSL 1P0I 2XQF 2XMB 2WIJ 2WIK 3DJY 1XLW 2WIG 1XLU 2WIF 1XLV 2XQG 2XMD 2WID 1P0P 3DKK 4B0O 1P0M 4AXB 2XQJ 2XQK 2XMC 1P0Q 4B0P 4AQD 2Y1K 2XQI 4BBZ 2XMG 2J4C 2PM8 3O9M 2WIL

Position

3q26.1-q26.2

AA seq 602 aa
MHSKVTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIP
YAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDC
LYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALG
FLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPG
SHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEI
LLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVY
GAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDV
VGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLER
RDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMT
KLRAQQCRFWTSFFPKVLEMTGNIDEAEWEWKAGFHRWNNYMMDWKNQFNDYTSKKESCV
GL

NT seq 1809 nt +upstreamnt +downstreamnt
atgcatagcaaagtcacaatcatatgcatcagatttctcttttggtttcttttgctctgc
atgcttattgggaagtcacatactgaagatgacatcataattgcaacaaagaatggaaaa
gtcagagggatgaacttgacagtttttggtggcacggtaacagcctttcttggaattccc
tatgcacagccacctcttggtagacttcgattcaaaaagccacagtctctgaccaagtgg
tctgatatttggaatgccacaaaatatgcaaattcttgctgtcagaacatagatcaaagt
tttccaggcttccatggatcagagatgtggaacccaaacactgacctcagtgaagactgt
ttatatctaaatgtatggattccagcacctaaaccaaaaaatgccactgtattgatatgg
atttatggtggtggttttcaaactggaacatcatctttacatgtttatgatggcaagttt
ctggctcgggttgaaagagttattgtagtgtcaatgaactatagggtgggtgccctagga
ttcttagctttgccaggaaatcctgaggctccagggaacatgggtttatttgatcaacag
ttggctcttcagtgggttcaaaaaaatatagcagcctttggtggaaatcctaaaagtgta
actctctttggagaaagtgcaggagcagcttcagttagcctgcatttgctttctcctgga
agccattcattgttcaccagagccattctgcaaagtggatcctttaatgctccttgggcg
gtaacatctctttatgaagctaggaacagaacgttgaacttagctaaattgactggttgc
tctagagagaatgagactgaaataatcaagtgtcttagaaataaagatccccaagaaatt
cttctgaatgaagcatttgttgtcccctatgggactcctttgtcagtaaactttggtccg
accgtggatggtgattttctcactgacatgccagacatattacttgaacttggacaattt
aaaaaaacccagattttggtgggtgttaataaagatgaagggacagcttttttagtctat
ggtgctcctggcttcagcaaagataacaatagtatcataactagaaaagaatttcaggaa
ggtttaaaaatattttttccaggagtgagtgagtttggaaaggaatccatcctttttcat
tacacagactgggtagatgatcagagacctgaaaactaccgtgaggccttgggtgatgtt
gttggggattataatttcatatgccctgccttggagttcaccaagaagttctcagaatgg
ggaaataatgcctttttctactattttgaacaccgatcctccaaacttccgtggccagaa
tggatgggagtgatgcatggctatgaaattgaatttgtctttggtttacctctggaaaga
agagataattacacaaaagccgaggaaattttgagtagatccatagtgaaacggtgggca
aattttgcaaaatatgggaatccaaatgagactcagaacaatagcacaagctggcctgtc
ttcaaaagcactgaacaaaaatatctaaccttgaatacagagtcaacaagaataatgacg
aaactacgtgctcaacaatgtcgattctggacatcattttttccaaaagtcttggaaatg
acaggaaatattgatgaagcagaatgggagtggaaagcaggattccatcgctggaacaat
tacatgatggactggaaaaatcaatttaacgattacactagcaagaaagaaagttgtgtg
ggtctctaa

All links

Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Drug (5)   
   KEGG DRUG (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (34)   
   PDB (34)   
Protein domain (3)   
   Pfam (3)   
All databases (86)   

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