KEGG   Homo sapiens (human): 59345Help
Entry
59345             CDS       T01001                                 

Gene name
GNB4, CMTD1F
Definition
(RefSeq) G protein subunit beta 4
  KO
K04538  guanine nucleotide-binding protein subunit beta-4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05167  Kaposi's sarcoma-associated herpesvirus infection
hsa05200  Pathways in cancer
Network
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CXCR-GNB/G-PI3K-JNK signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00206  KSHV vGPCR to host-cell-protein activation
Disease
H00264  Charcot-Marie-Tooth disease (CMT)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    59345 (GNB4)
   04371 Apelin signaling pathway
    59345 (GNB4)
   04151 PI3K-Akt signaling pathway
    59345 (GNB4)
 Organismal Systems
  Immune system
   04062 Chemokine signaling pathway
    59345 (GNB4)
  Endocrine system
   04926 Relaxin signaling pathway
    59345 (GNB4)
  Nervous system
   04724 Glutamatergic synapse
    59345 (GNB4)
   04727 GABAergic synapse
    59345 (GNB4)
   04725 Cholinergic synapse
    59345 (GNB4)
   04728 Dopaminergic synapse
    59345 (GNB4)
   04726 Serotonergic synapse
    59345 (GNB4)
   04723 Retrograde endocannabinoid signaling
    59345 (GNB4)
  Environmental adaptation
   04713 Circadian entrainment
    59345 (GNB4)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    59345 (GNB4)
  Substance dependence
   05032 Morphine addiction
    59345 (GNB4)
   05034 Alcoholism
    59345 (GNB4)
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    59345 (GNB4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   59345 (GNB4)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    59345 (GNB4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: WD40 ANAPC4_WD40 WD40_like eIF2A Spore_YhcN_YlaJ
Motif
Other DBs
NCBI-GeneID: 59345
NCBI-ProteinID: NP_067642
OMIM: 610863
HGNC: 20731
Ensembl: ENSG00000114450
Vega: OTTHUMG00000157440
Pharos: Q9HAV0(Tbio)
UniProt: Q9HAV0
Position
3q26.33
AA seq 340 aa AA seqDB search
MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYA
MHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTF
TGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYA
FATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL
KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN
NT seq 1023 nt NT seq  +upstreamnt  +downstreamnt
atgagcgaactggaacagttgaggcaagaagcagaacaactgcggaatcagattcaggat
gctcggaaagcatgtaatgatgcaacgcttgttcagattacatcaaatatggactctgtg
ggtcgaatacaaatgcgaacaagacgtacactgaggggccacctagctaaaatctatgct
atgcattggggatacgattccaggctgctagtcagtgcttctcaagatggaaaattaatt
atttgggatagctatacaacaaataagatgcatgctattcctttgaggtcctcctgggtg
atgacctgtgcttatgctccctctggtaattatgttgcctgtggaggcttggacaacatc
tgctctatatataacttaaagaccagagagggaaatgtgagagtaagccgagagttgcca
ggtcacacagggtacttgtcctgctgtcgttttttagatgacagccaaattgttacaagt
tcaggagatacaacttgtgctttatgggacatcgaaactgcccagcagaccaccacattc
actgggcattctggagatgtgatgagtctttctttgagtcctgacatgaggacttttgtt
tctggtgcttgtgatgcctcttccaaattatgggatattcgagatggaatgtgtagacag
tctttcacgggacatgtctcagatatcaatgctgtcagttttttcccaaatggatatgcc
ttcgccactggctctgatgatgccacttgccggctctttgaccttcgtgcagatcaagag
ttattattgtattctcatgacaatatcatctgtggaatcacttctgtagccttctcaaaa
agtgggcgtctcttgttggctggttacgatgactttaattgtaatgtatgggacacgcta
aaaggagatcgtgcaggtgtccttgctggtcatgacaaccgtgtgagctgcttaggtgta
actgatgatggcatggctgtggcaacaggctcttgggacagttttcttagaatctggaat
taa

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