KEGG T01001: 6011

Homo sapiens (human): 6011

Entry

6011 CDS T01001

Gene name

GRK1, GPRK1, RHOK, RK

Definition

G protein-coupled receptor kinase 1 (EC:2.7.11.14)

Orthology

K00909

rhodopsin kinase [EC:2.7.11.14]

Organism

hsa Homo sapiens (human)

Pathway

hsa04062	Chemokine signaling pathway
hsa04144	Endocytosis
hsa04744	Phototransduction

Disease

H00787

Congenital stationary night blindness (CSNB)

Class

Cellular Processes; Transport and catabolism; Endocytosis [PATH:hsa04144]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:hsa04062]
Organismal Systems; Sensory system; Phototransduction [PATH:hsa04744]

SSDB

Motif

Pfam:

Pkinase Pkinase_Tyr RGS Kinase-like

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

UniProt:

Position

13q34

AA seq 563 aa
MDFGSLETVVANSAFIAARGSFDGSSSQPSRDKKYLAKLKLPPLSKCESLRDSLSLEFES
VCLEQPIGKKLFQQFLQSAEKHLPALELWKDIEDYDTADNDLQPQKAQTILAQYLDPQAK
LFCSFLDEGIVAKFKEGPVEIQDGLFQPLLQATLAHLGQAPFQEYLGSLYFLRFLQWKWL
EAQPMGEDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKK
ILMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQ
IICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMA
PELLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFS
QASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIPDSKTVY
AKDIQDVGAFSTVKGVAFDKTDTEFFQEFATGNCPIPWQEEMIETGIFGELNVWRSDGQM
PDDMKGISGGSSSSSKSGMCLVS

NT seq 1692 nt +upstreamnt +downstreamnt
atggatttcgggtctttggagaccgtggtggccaactctgccttcatcgccgcccgaggc
agctttgacggcagcagctcccaaccctcccgggacaagaagtacctggccaagctcaag
ctgcccccgctgtccaagtgtgagtccctccgcgacagcctcagcctggagtttgagagt
gtgtgcttggagcagcccatcggcaagaagctctttcagcagttcctacaatcggcagag
aagcacctgccggccctggagctctggaaagacatcgaggactatgacacggcagacaat
gacctccagccacagaaggcccagaccatcctggcccagtacctggacccccaggccaaa
ctcttctgcagcttcctggatgaggggatagtggcgaagtttaaggaggggcctgtggag
atccaggacgggctcttccagcccctgctgcaggccaccctggcacacctgggccaagcc
cccttccaggagtacctgggcagcctgtacttcctgaggttcctgcagtggaagtggctg
gaagcccagcccatgggggaggactggttcctggacttcagggtcctggggaaagggggc
ttcggggaggtgtcggcctgccagatgaaggcgaccggcaagctgtatgcctgcaagaag
ctgaacaagaagcggctgaagaagaggaagggctaccagggtgctatggtggagaagaag
attctgatgaaagtacacagcaggttcatcgtgtctctggcctatgcgtttgaaaccaaa
gccgacctctgtctggtgatgaccatcatgaacggaggtgacatcaggtaccacatctac
aacgtgaatgaggagaaccctggcttcccggagccgcgcgccctcttctacacggcgcag
atcatctgcggcctggagcacctgcaccagaggcggatcgtctaccgcgacctcaagccc
gagaacgtgctgctggacaatgacggcaatgtccggatctctgaccttgggctggccgtg
gagctgctggacggacagagcaagaccaagggctacgcagggaccccaggtttcatggcc
cccgagctcctgcagggcgaggagtacgacttctccgtggactactttgccctgggggtc
accctgtatgagatgattgcggccagaggacccttccgagcccgtggagagaaggtggag
aacaaggagctgaagcaccggatcatctcagagcccgtgaagtaccctgataagttcagc
caggccagcaaggacttctgcgaggcgctgctggagaaggacccggagaagcgcctgggg
ttcagagatgagacctgcgacaagctccgtgcccaccccctcttcaaggaccttaactgg
aggcagctggaggctgggatgctgatgccccctttcatcccagactccaaaactgtctac
gcaaaggatattcaggacgtgggtgccttttccaccgtcaaaggtgtggcctttgacaaa
acagacacagaattctttcaggaatttgccactggcaactgccccatcccctggcaggag
gagatgatcgagacgggcatctttggcgagctgaacgtgtggcgctcggacggtcagatg
ccggacgacatgaagggcatctccgggggctccagctcctcgtccaagtcagggatgtgt
ctggtttcctag

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UniGene (2)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
Protein domain (4)   
   Pfam (4)   
All databases (42)   

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