KEGG T01001: 6041

Homo sapiens (human): 6041

Entry

6041 CDS T01001

Gene name

RNASEL, PRCA1, RNS4

Definition

ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) (EC:3.1.26.- 3.1.27.-)

Orthology

K01165

ribonuclease L

Organism

hsa Homo sapiens (human)

Pathway

hsa05160	Hepatitis C
hsa05164	Influenza A
hsa05168	Herpes simplex infection

Class

Human Diseases; Infectious diseases; Influenza A [PATH:hsa05164]
Human Diseases; Infectious diseases; Hepatitis C [PATH:hsa05160]
Human Diseases; Infectious diseases; Herpes simplex infection [PATH:hsa05168]

SSDB

Motif

Pfam:

Ank_2 Ank Ank_4 Ribonuc_2-5A Ank_5 Ank_3 Pkinase Pkinase_Tyr Kdo Shigella_OspC RIO1 Choline_kinase RUN DUF1949

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1WDY 4G8K 4G8L

Position

1q25

AA seq 741 aa
MESRDHNNPQEGPTSSSGRRAAVEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGW
TPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNE
CDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGH
VEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGK
TPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTD
CGDLVMTARRNYDHSLVKVLLSHGAKEDFHPPAEDWKPQSSHWGAALKDLHRIYRPMIGK
LKFFIDEKYKIADTSEGGIYLGFYEKQEVAVKTFCEGSPRAQREVSCLQSSRENSHLVTF
YGSESHRGHLFVCVTLCEQTLEACLDVHRGEDVENEEDEFARNVLSSIFKAVQELHLSCG
YTHQDLQPQNILIDSKKAAHLADFDKSIKWAGDPQEVKRDLEDLGRLVLYVVKKGSISFE
DLKAQSNEEVVQLSPDEETKDLIHRLFHPGEHVRDCLSDLLGHPFFWTWESRYRTLRNVG
NESDIKTRKSESEILRLLQPGPSEHSKSFDKWTTKINECVMKKMNKFYEKRGNFYQNTVG
DLLKFIRNLGEHIDEEKHKKMKLKIGDPSLYFQKTFPDLVIYVYTKLQNTEYRKHFPQTH
SPNKPQCDGAGGASGLASPGC

NT seq 2226 nt +upstreamnt +downstreamnt
atggagagcagggatcataacaacccccaggagggacccacgtcctccagcggtagaagg
gctgcagtggaagacaatcacttgctgattaaagctgttcaaaacgaagatgttgacctg
gtccagcaattgctggaaggtggagccaatgttaatttccaggaagaggaagggggctgg
acacctctgcataacgcagtacaaatgagcagggaggacattgtggaacttctgcttcgt
catggtgctgaccctgttctgaggaagaagaatggggccacgccttttatcctcgcagcg
attgcggggagcgtgaagctgctgaaacttttcctttctaaaggagcagatgtcaatgag
tgtgatttttatggcttcacagccttcatggaagccgctgtgtatggtaaggtcaaagcc
ctaaaattcctttataagagaggagcaaatgtgaatttgaggcgaaagacaaaggaggat
caagagcggctgaggaaaggaggggccacagctctcatggacgctgctgaaaaaggacac
gtagaggtcttgaagattctccttgatgagatgggggcagatgtaaacgcctgtgacaat
atgggcagaaatgccttgatccatgctctcctgagctctgacgatagtgatgtggaggct
attacgcatctgctgctggaccatggggctgatgtcaatgtgaggggagaaagagggaag
actcccctgatcctggcagtggagaagaagcacttgggtttggtgcagaggcttctggag
caagagcacatagagattaatgacacagacagtgatggcaaaacagcactgctgcttgct
gttgaactcaaactgaagaaaatcgccgagttgctgtgcaaacgtggagccagtacagat
tgtggggatcttgttatgacagcgaggcggaattatgaccattcccttgtgaaggttctt
ctctctcatggagccaaagaagattttcaccctcctgctgaagactggaagcctcagagc
tcacactggggggcagccctgaaggatctccacagaatataccgccctatgattggcaaa
ctcaagttctttattgatgaaaaatacaaaattgctgatacttcagaaggaggcatctac
ctggggttctatgagaagcaagaagtagctgtgaagacgttctgtgagggcagcccacgt
gcacagcgggaagtctcttgtctgcaaagcagccgagagaacagtcacttggtgacattc
tatgggagtgagagccacaggggccacttgtttgtgtgtgtcaccctctgtgagcagact
ctggaagcgtgtttggatgtgcacagaggggaagatgtggaaaatgaggaagatgaattt
gcccgaaatgtcctgtcatctatatttaaggctgttcaagaactacacttgtcctgtgga
tacacccaccaggatctgcaaccacaaaacatcttaatagattctaagaaagctgctcac
ctggcagattttgataagagcatcaagtgggctggagatccacaggaagtcaagagagat
ctagaggaccttggacggctggtcctctatgtggtaaagaagggaagcatctcatttgag
gatctgaaagctcaaagtaatgaagaggtggttcaactttctccagatgaggaaactaag
gacctcattcatcgtctcttccatcctggggaacatgtgagggactgtctgagtgacctg
ctgggtcatcccttcttttggacttgggagagccgctataggacgcttcggaatgtggga
aatgaatccgacatcaaaacacgaaaatctgaaagtgagatcctcagactactgcaacct
gggccttctgaacattccaaaagttttgacaagtggacgactaagattaatgaatgtgtt
atgaaaaaaatgaataagttttatgaaaaaagaggcaatttctaccagaacactgtgggt
gatctgctaaagttcatccggaatttgggagaacacattgatgaagaaaagcataaaaag
atgaaattaaaaattggagacccttccctgtattttcagaagacatttccagatctggtg
atctatgtctacacaaaactacagaacacagaatatagaaagcatttcccccaaacccac
agtccaaacaagcctcagtgtgatggagctggtggggccagtgggttggccagccctggg
tgctga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (27)   
   RefSeq(nuc) (1)   
   GenBank (13)   
   EMBL (13)   
3D Structure (3)   
   PDB (3)   
Protein domain (14)   
   Pfam (14)   
All databases (66)   

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