KEGG T01001: 60495

Homo sapiens (human): 60495

Entry

60495 CDS T01001

Gene name

HPSE2, HPA2, HPR2, UFS, UFS1

Definition

heparanase 2

Orthology

K07965

heparanase 2 [EC:3.2.1.-]

Organism

hsa Homo sapiens (human)

Pathway

hsa00531	Glycosaminoglycan degradation
hsa01100	Metabolic pathways
hsa05205	Proteoglycans in cancer

Module

hsa_M00078

Heparan sulfate degradation

Disease

H00753

Urofacial syndrome

Class

Metabolism; Glycan biosynthesis and metabolism; Glycosaminoglycan degradation [PATH:hsa00531]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:hsa05205]

SSDB

Motif

Pfam:

Glyco_hydro_79n

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

UniProt:

Position

10q23-q24

AA seq 534 aa
MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTL
ILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRT
DFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREK
AAQMHLVLLKEQFSNTYSNLILTEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSR
ASLYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLS
DQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVV
IRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKL
RIYAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSK
SVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR

NT seq 1605 nt +upstreamnt +downstreamnt
atgagggtgctttgtgccttccctgaagccatgccctccagcaactcccgcccccccgcg
tgcctagccccgggggctctctacttggctctgttgctccatctctccctttcctcccag
gctggagacaggagacccttgcctgtagacagagctgcaggtttgaaggaaaagaccctg
attctacttgatgtgagcaccaagaacccagtcaggacagtcaatgagaacttcctctct
ctgcagctggatccgtccatcattcatgatggctggctcgatttcctaagctccaagcgc
ttggtgaccctggcccggggactttcgcccgcctttctgcgcttcgggggcaaaaggacc
gacttcctgcagttccagaacctgaggaacccggcgaaaagccgcgggggcccgggcccg
gattactatctcaaaaactatgaggatgacattgttcgaagtgatgttgccttagataaa
cagaaaggctgcaagattgcccagcaccctgatgttatgctggagctccaaagggagaag
gcagctcagatgcatctggttcttctaaaggagcaattctccaatacttacagtaatctc
atattaacagagccaaataactatcggaccatgcatggccgggcagtaaatggcagccag
ttgggaaaggattacatccagctgaagagcctgttgcagcccatccggatttattccaga
gccagcttatatggccctaatattgggcggccgaggaagaatgtcatcgccctcctagat
ggattcatgaaggtggcaggaagtacagtagatgcagttacctggcaacattgctacatt
gatggccgggtggtcaaggtgatggacttcctgaaaactcgcctgttagacacactctct
gaccagattaggaaaattcagaaagtggttaatacatacactccaggaaagaagatttgg
cttgaaggtgtggtgaccacctcagctggaggcacaaacaatctatccgattcctatgct
gcaggattcttatggttgaacactttaggaatgctggccaatcagggcattgatgtcgtg
atacggcactcattttttgaccatggatacaatcacctcgtggaccagaattttaaccca
ttaccagactactggctctctctcctctacaagcgcctgatcggccccaaagtcttggct
gtgcatgtggctgggctccagcggaagccacggcctggccgagtgatccgggacaaacta
aggatttatgctcactgcacaaaccaccacaaccacaactacgttcgtgggtccattaca
ctttttatcatcaacttgcatcgatcaagaaagaaaatcaagctggctgggactctcaga
gacaagctggttcaccagtacctgctgcagccctatgggcaggagggcctaaagtccaag
tcagtgcaactgaatggccagcccttagtgatggtggacgacgggaccctcccagaattg
aagccccgcccccttcgggccggccggacattggtcatccctccagtcaccatgggcttt
tatgtggtcaagaatgtcaatgctttggcctgccgctaccgataa

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (3)   
   HGNC (1)   
   HPRD (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   RefSeq(pep) (4)   
DNA sequence (24)   
   RefSeq(nuc) (4)   
   GenBank (10)   
   EMBL (10)   
Protein domain (1)   
   Pfam (1)   
All databases (60)   

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