KEGG   Homo sapiens (human): 6195Help
Entry
6195              CDS       T01001                                 

Gene name
RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1
Definition
ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)
Orthology
K04373  
p90 ribosomal S6 kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
MAPK signaling pathway
Oocyte meiosis
mTOR signaling pathway
Long-term potentiation
Neurotrophin signaling pathway
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    6195 (RPS6KA1)
   04150 mTOR signaling pathway
    6195 (RPS6KA1)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    6195 (RPS6KA1)
 Organismal Systems
  Endocrine system
   04914 Progesterone-mediated oocyte maturation
    6195 (RPS6KA1)
  Nervous system
   04720 Long-term potentiation
    6195 (RPS6KA1)
   04722 Neurotrophin signaling pathway
    6195 (RPS6KA1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     6195 (RPS6KA1)
Protein kinases [BR:hsa01001]
 Serine/threonine protein kinases: AGC group
  RSK family [Table]
   6195 (RPS6KA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
1p
AA seq 744 aa AA seqDB search
MEQDPKPPRLRLWALIPWLPRKQRPRISQTSLPVPGPGSGPQRDSDEGVLKEISITHHVK
AGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKM
ERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL
ALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAP
EVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQS
LLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYF
DTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQAPLHSVVQQLHGKN
LVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPN
IITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGV
VHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY
DEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDL
VSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYSALNSSKPT
PQLKPIESSILAQRRVRKLPSTTL
NT seq 2235 nt NT seq  +upstreamnt  +downstreamnt
atggagcaggatcccaagccgccccgtctgcggctctgggccctgatcccctggcttccc
aggaagcagcggcccaggatcagccagacctctctgcctgtccctggccctggctctggc
ccccagcgggactcggatgagggcgtcctcaaggagatctccatcacgcaccacgtcaag
gctggctctgagaaggctgatccatcccatttcgagctcctcaaggttctgggccaggga
tcctttggcaaagtcttcctggtgcggaaagtcacccggcctgacagtgggcacctgtat
gctatgaaggtgctgaagaaggcaacgctgaaagtacgtgaccgcgtccggaccaagatg
gagagagacatcctggctgatgtaaatcacccattcgtggtgaagctgcactatgccttc
cagaccgagggcaagctctatctcattctggacttcctgcgtggtggggacctcttcacc
cggctctcaaaagaggtgatgttcacggaggaggatgtgaagttttacctggccgagctg
gctctgggcctggatcacctgcacagcctgggtatcatttacagagacctcaagcctgag
aacatccttctggatgaggagggccacatcaaactcactgactttggcctgagcaaagag
gccattgaccacgagaagaaggcctattctttctgcgggacagtggagtacatggcccct
gaggtcgtcaaccgccagggccactcccatagtgcggactggtggtcctatggggtgttg
atgtttgagatgctgacgggctccctgcccttccaggggaaggaccggaaggagaccatg
acactgattctgaaggcgaagctaggcatgccccagtttctgagcactgaagcccagagc
ctcttgcgggccctgttcaagcggaatcctgccaaccggctcggctccggccctgatggg
gcagaggaaatcaagcggcatgtcttctactccaccattgactggaataagctataccgt
cgtgagatcaagccacccttcaagccagcagtggctcagcctgatgacaccttctacttt
gacaccgagttcacgtcccgcacacccaaggattccccaggcatcccccccagcgctggg
gcccatcagctgttccggggcttcagcttcgtggccaccggcctgatggaagacgacggc
aagcctcgtgccccgcaggcacccctgcactcggtggtacagcaactccatgggaagaac
ctggtttttagtgacggctacgtggtaaaggagacaattggtgtgggctcctactctgag
tgcaagcgctgtgtccacaaggccaccaacatggagtatgctgtcaaggtcattgataag
agcaagcgggatccttcagaagagattgagattcttctgcggtatggccagcaccccaac
atcatcactctgaaagatgtgtatgatgatggcaaacacgtgtacctggtgacagagctg
atgcggggtggggagctgctggacaagatcctgcggcagaagttcttctcagagcgggag
gccagctttgtcctgcacaccattggcaaaactgtggagtatctgcactcacagggggtt
gtgcacagggacctgaagcccagcaacatcctgtatgtggacgagtccgggaatcccgag
tgcctgcgcatctgtgactttggttttgccaaacagctgcgggctgagaatgggctcctc
atgacaccttgctacacagccaactttgtggcgcctgaggtgctgaagcgccagggctac
gatgaaggctgcgacatctggagcctgggcattctgctgtacaccatgctggcaggatat
actccatttgccaacggtcccagtgacacaccagaggaaatcctaacccggatcggcagt
gggaagtttaccctcagtgggggaaattggaacacagtttcagagacagccaaggacctg
gtgtccaagatgctacacgtggatccccaccagcgcctcacagctaagcaggttctgcag
catccatgggtcacccagaaagacaagcttccccaaagccagctgtcccaccaggaccta
cagcttgtgaagggagccatggctgccacgtactccgcactcaacagctccaagcccacc
ccccagctgaagcccatcgagtcatccatcctggcccagcggcgagtgaggaagttgcca
tccaccaccctgtga

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