KEGG T01001: 64326

Homo sapiens (human): 64326

Entry

64326 CDS T01001

Gene name

RFWD2, COP1, RNF200

Definition

ring finger and WD repeat domain 2, E3 ubiquitin protein ligase

Orthology

K10143

E3 ubiquitin-protein ligase RFWD2 [EC:6.3.2.19]

Organism

hsa Homo sapiens (human)

Pathway

hsa04115	p53 signaling pathway
hsa04120	Ubiquitin mediated proteolysis

Class

Genetic Information Processing; Folding, sorting and degradation; Ubiquitin mediated proteolysis [PATH:hsa04120]
Cellular Processes; Cell growth and death; p53 signaling pathway [PATH:hsa04115]

SSDB

Motif

Pfam:

WD40 zf-C3HC4 zf-C3HC4_2 zf-C3HC4_3 zf-RING_2 zf-RING_5 zf-C3HC4_4 zf-RING_UBOX zf-RING_4 zf-rbx1

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

1q25.1-q25.2

AA seq 707 aa
MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
DHLYPNFLVNELILKQKQRFEEKRFKLDHSNGHRWQIFQDWLGTDQDNLDLANVNLMLEL
LVQKKKQLEAESHAAQLQILMEFLKVARRNKREEMSGLYSPVSEDSTVPQFEAPSPSHSS
IIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSR
TASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKK
IKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQ
RSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFS
PSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKL
WNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVK
SVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKVLELV

NT seq 2124 nt +upstreamnt +downstreamnt
atgtctggtagccgccaggccgggtcgggctccgctgggacaagccccgggtcctcggcg
gcctcctcggtgacttccgcctcctcgtctttatcctcttccccgtcgccgccttccgtg
gcggtttcggcggcagcgctggtgtccggcggggtggcccaggccgccggctcgggcggc
ctcgggggcccggtgcggcctgtgttggtggcgcccgccgtatcgggtagcggcggcggg
gcggtgtccacgggcctgtcccggcacagctgcgcggccaggcccagcgccggcgtagga
ggcagcagctccagcctaggcagcggcagcaggaagcgacctctcctcgcccccctctgc
aacgggctcatcaactcctacgaggacaaaagcaacgacttcgtatgccccatctgcttt
gatatgattgaagaagcatacatgacaaaatgtggccacagcttttgctacaagtgtatt
catcagagtttggaggacaataatagatgtcccaagtgtaactatgttgtggacaatatt
gaccatctgtatcctaatttcttggtgaatgaactcattcttaaacagaagcaaagattt
gaggaaaagaggttcaaattggaccactcaaatggccacaggtggcagatatttcaagat
tggttgggaactgaccaagataaccttgatttggccaatgtcaatcttatgttggagtta
ctagtgcagaagaagaaacaactggaagcagaatcacatgcagcccaactacagattctt
atggaattcctcaaggttgcaagaagaaataagagagaggaaatgagtggcttatactct
cctgtcagtgaggatagcacagtgcctcaatttgaagctccttctccatcacacagtagt
attattgattccacagaatacagccaacctccaggtttcagtggcagttctcagacaaag
aaacagccttggtataatagcacgttagcatcaagacgaaaacgacttactgctcatttt
gaagacttggagcagtgttacttttctacaaggatgtctcgtatctcagatgacagtcga
actgcaagccagttggatgaatttcaggaatgcttgtccaagtttactcgatataattca
gtacgacctttagccacattgtcatatgctagtgatctctataatggttccagtatagtc
tctagtattgaatttgaccgggattgtgactattttgcgattgctggagttacaaagaag
attaaagtctatgaatatgacactgtcatccaggatgcagtggatattcattaccctgag
aatgaaatgacctgcaattcgaaaatcagctgtatcagttggagtagttaccataagaac
ctgttagctagcagtgattatgaaggcactgttattttatgggatggattcacaggacag
aggtcaaaggtctatcaggagcatgagaagaggtgttggagtgttgactttaatttgatg
gatcctaaactcttggcttcaggttctgatgatgcaaaagtgaagctgtggtctaccaat
ctagacaactcagtggcaagcattgaggcaaaggctaatgtgtgctgtgttaaattcagc
ccctcttccagataccatttggctttcggctgtgcagatcactgtgtccactactatgat
cttcgtaacactaaacagccaatcatggtattcaaaggacaccgtaaagcagtctcttat
gcaaagtttgtgagtggtgaggaaattgtctctgcctcaacagacagtcagctaaaactg
tggaatgtagggaaaccatactgcctacgttccttcaagggtcatatcaatgaaaaaaac
tttgtaggcctggcttccaatggagattatatagcttgtggaagtgaaaataactctctc
tacctgtactataaaggactttctaagactttgctaacttttaagtttgatacagtcaaa
agtgttctcgacaaagaccgaaaagaagatgatacaaatgaatttgttagtgctgtgtgc
tggagggcactaccagatggggagtccaatgtgctgattgctgctaacagtcagggtaca
attaaggtgctagaattggtatga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (22)   
   RefSeq(nuc) (2)   
   GenBank (10)   
   EMBL (10)   
Protein domain (10)   
   Pfam (10)   
All databases (57)   

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