KEGG   Homo sapiens (human): 6470Help
Entry
6470              CDS       T01001                                 

Gene name
SHMT1, CSHMT, SHMT
Definition
serine hydroxymethyltransferase 1 (soluble) (EC:2.1.2.1)
Orthology
K00600  
glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
hsa  Homo sapiens (human)
Pathway
Glycine, serine and threonine metabolism
Cyanoamino acid metabolism
Glyoxylate and dicarboxylate metabolism
One carbon pool by folate
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
Module
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    6470 (SHMT1)
   01230 Biosynthesis of amino acids
    6470 (SHMT1)
  Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    6470 (SHMT1)
  Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    6470 (SHMT1)
  Metabolism of other amino acids
   00460 Cyanoamino acid metabolism
    6470 (SHMT1)
  Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    6470 (SHMT1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     6470 (SHMT1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
17p11.2
AA seq 345 aa AA seqDB search
MGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLI
IAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKT
LRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQ
AMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLE
ACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSD
TGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
NT seq 1038 nt NT seq  +upstreamnt  +downstreamnt
atgggcctggaccttccggatgggggccacctgacccatgggttcatgacagacaagaag
aaaatctctgccacgtccatcttctttgaatctatgccctacaaggtgaacccagatact
ggctacatcaactatgaccagctggaggagaacgcacgcctcttccacccgaagctgatc
atcgcaggaaccagctgctactcccgaaacctggaatatgcccggctacggaagattgca
gatgagaacggggcgtatctcatggcggacatggctcacatcagcgggctggtggcggct
ggcgtggtgccctccccatttgaacactgccatgtggtgaccaccaccactcacaagacc
ctgcgaggctgccgagctggcatgatcttctacaggaaaggagtgaaaagtgtggatccc
aagactggcaaagagattctgtacaacctggagtctcttatcaattctgctgtgttccct
ggcctgcagggaggtccccacaaccacgccattgctggggttgctgtggcactgaagcaa
gctatgactctggaatttaaagtttatcaacaccaggtggtggccaactgcagggctctg
tctgaggccctgacggagctgggctacaaaatagtcacaggtggttctgacaaccatttg
atccttgtggatctccgttccaaaggcacagatggtggaagggctgagaaggtgctagaa
gcctgttctattgcctgcaacaagaacacctgtccaggtgacagaagcgctctgcggccc
agtggactgcggctggggaccccagcactgacgtcccgtggacttttggaaaaagacttc
caaaaagtagcccactttattcacagagggatagagctgaccctgcagatccagagcgac
actggtgtcagagccaccctgaaagagttcaaggagagactggcaggggataagtaccag
gcggccgtgcaggctctccgggaggaggttgagagcttcgcctctctcttccctctgcct
ggcctgcctgacttctaa

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