KEGG T01001: 65266

Homo sapiens (human): 65266

Entry

65266 CDS T01001

Gene name

WNK4, PHA2B, PRKWNK4

Definition

WNK lysine deficient protein kinase 4 (EC:2.7.11.1)

Orthology

K08867

WNK lysine deficient protein kinase [EC:2.7.11.1]

Organism

hsa Homo sapiens (human)

Disease

H00243

Hyperkalemic distal renal tubular acidosis (RTA type 4)

Class

SSDB

Motif

Pfam:

Pkinase Pkinase_Tyr OSR1_C PKK

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Position

17q21-q22

AA seq 1243 aa
MLASPATETTVLMSQTEADLALRPPPPLGTAGQPRLGPPPRRARRFSGKAEPRPRSSRLS
RRSSVDLGLLSSWSLPASPAPDPPDPPDSAGPGPARSPPPSSKEPPEGTWTEGAPVKAAE
DSARPELPDSAVGPGSREPLRVPEAVALERRREQEEKEDMETQAVATSPDGRYLKFDIEI
GRGSFKTVYRGLDTDTTVEVAWCELQTRKLSRAERQRFSEEVEMLKGLQHPNIVRFYDSW
KSVLRGQVCIVLVTELMTSGTLKTYLRRFREMKPRVLQRWSRQILRGLHFLHSRVPPILH
RDLKCDNVFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDEAVDVYA
FGMCMLEMATSEYPYSECQNAAQIYRKVTSGRKPNSFHKVKIPEVKEIIEGCIRTDKNER
FTIQDLLAHAFFREERGVHVELAEEDDGEKPGLKLWLRMEDARRGGRPRDNQAIEFLFQL
GRDAAEEVAQEMVALGLVCEADYQPVARAVRERVAAIQRKREKLRKARELEALPPEPGPP
PATVPMAPGPPSVFPPEPEEPEADQHQPFLFRHASYSSTTSDCETDGYLSSSGFLDASDP
ALQPPGGVPSSLAESHLCLPSAFALSIPRSGPGSDFSPGDSYASDAASGLSDVGEGMGQM
RRPPGRNLRRRPRSRLRVTSVSDQNDRVVECQLQTHNSKMVTFRFDLDGDSPEEIAAAMV
YNEFILPSERDGFLRRIREIIQRVETLLKRDTGPMEAAEDTLSPQEEPAPLPALPVPLPD
PSNEELQSSTSLEHRSWTAFSTSSSSPGTPLSPGNPFSPGTPISPGPIFPITSPPCHPSP
SPFSPISSQVSSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTSPPTFSPTCSQVT
LSSPFFPPCPSTSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSPL
PSLPLPPPVAPGGQESPSPHTAEVESEASPPPARPLPGEARLAPISEEGKPQLVGRFQVT
SSKEPAEPLPLQPTSPTLSGSPKPSTPQLTSESSDTEDSAGGGPETREALAESDRAAEGL
GAGVEEEGDDGKEPQVGGSPQPLSHPSPVWMNYSYSSLCLSSEESESSGEDEEFWAELQS
LRQKHLSEVETLQTLQKKEIEDLYSRLGKQPPPGIVAPAAMLSSRQRRLSKGSFPTSRRN
SLQRSEPPGPGIMRRNSLSGSSTGSQEQRASKGVTFAGDVGRM

NT seq 3732 nt +upstreamnt +downstreamnt
atgttggcatccccggccacggagaccaccgtcctcatgtcccagactgaggccgacctg
gccctgcggcccccgcctcctcttggcaccgcggggcagccccgcctcgggccccctcct
cgccgagcgcgccgcttctccgggaaggctgagccccggccgcgctcttctcgtctcagc
cgccgtagctcagtcgacttggggctgctgagctcttggtccctgccagcctcacccgct
ccggacccccccgatcctccggactccgctggtcctggccccgcgaggagcccaccgcct
agctccaaagaaccccccgagggcacgtggaccgagggagcccctgtgaaggctgcggaa
gactccgcgcgtcccgagctcccggactctgcagtgggcccggggtccagggagccgcta
agggtccctgaagctgtggccctagagcggcggcgggagcaggaagaaaaggaggacatg
gagacccaggctgtggcaacgtcccccgatggccgatacctcaagtttgacatcgagatt
ggacgtggctccttcaagacggtgtatcgagggctagacaccgacaccacagtggaggtg
gcctggtgtgagctgcagactcggaaactgtctagagctgagcggcagcgcttctcagag
gaggtggagatgctcaaggggctgcagcaccccaacatcgtccgcttctatgattcgtgg
aagtcggtgctgaggggccaggtttgcatcgtgctggtcaccgaactcatgacctcgggc
acgctcaagacgtacctgaggcggttccgggagatgaagccgcgggtccttcagcgctgg
agccgccaaatcctgcggggacttcatttcctacactcccgggttcctcccatcctgcac
cgggatctcaagtgcgacaatgtctttatcacgggacctactggctctgtcaaaatcggg
gacctgggcctggccacgctcaagcgcgcctcctttgccaagagtgtcatcgggaccccg
gaattcatggcccccgagatgtacgaggaaaagtacgatgaggccgtggacgtgtacgcg
ttcggcatgtgcatgctggagatggccacctctgagtacccgtactccgagtgccagaat
gccgcgcaaatctaccgcaaggtcacttcgggcagaaagccgaacagcttccacaaggtg
aagatacccgaggtgaaggagatcattgaaggctgcatccgcacggataagaacgagagg
ttcaccatccaggacctcctggcccacgccttcttccgcgaggagcgcggtgtgcacgtg
gaactagcggaggaggacgacggcgagaagccgggcctcaagctctggctgcgcatggag
gacgcgcggcgcggggggcgcccacgggacaaccaggccatcgagttcctgttccagctg
ggccgggacgcggccgaggaggtggcacaggagatggtggctctgggcttggtctgtgaa
gccgattaccagccagtggcccgtgcagtacgtgaacgggttgctgccatccagcgaaag
cgtgagaagctgcgtaaagcaagggaattggaggcactcccaccagagccaggacctcca
ccagcaactgtgcccatggcccccggtccccccagtgtcttcccccctgagcctgaggag
ccagaggcagaccagcaccagcccttccttttccgccacgccagctactcatctaccact
tcggattgcgagactgatggctacctcagctcctccggcttcctggatgcctcagaccct
gcccttcagccccctgggggggtgccatccagcctggctgagtcccatctctgcctgccc
tcggcttttgccctatccattccacgttctggccctggaagtgacttttcccccggggac
agctatgcctcagatgcagcttcaggccttagcgatgtgggagaagggatgggacaaatg
aggagacccccagggaggaatctccggcgcagaccccgatcccggctgcgggtcactagt
gtctcagaccagaatgacagagtggttgagtgccagctacagacccataacagcaagatg
gtgaccttccgatttgatctggatggggacagcccggaagagattgcagctgccatggta
tataacgagttcattctgccttcggagcgagatggatttctcagacggattcgggagatt
atccagcgagtggagaccctgttgaagagagacactggccccatggaggctgctgaagac
accctaagcccccaggaggagccagcaccattacctgccctgcccgtccccctcccagac
ccatccaatgaagagctccagagcagcacctccctggagcacaggagctggacagccttc
tccacctcctcatcttctcctggaactcctttgtctcctggaaacccattttcccctgga
acccccatttccccaggtcccatcttccccatcacttctcccccatgtcatcccagcccc
tccccattctcccccatttcttcccaggtctcctcaaatccctctccacaccccaccagc
tctccacttccattctcctccagcacacccgagtttccggtcccactctctcagtgtccc
tggagttctctccccacgacttctccacctacgttctctcccacttgttctcaggtcact
cttagttcccctttctttcctccgtgcccctccacttcttccttcccctccaccacagca
gcccctctcctttctctggctagtgccttctcactggctgtgatgactgtggcccagtcc
ctgctgtccccctcacctgggctcctttcccagtctcctccagcccctcctagtcccctc
cctagcctgccccttccccctcccgttgctcctggtggccaggaaagcccttcaccccac
acagctgaggtggagagtgaggcctcaccacctcctgctcggcccctcccaggggaagcc
aggctggcgcccatctctgaagagggaaagccgcagcttgttgggcgtttccaagtgact
tcatccaaggaaccggctgagcctcttcccttgcagccaacatcccccactctctctggt
tctccaaaaccttcaacccctcagctcacttcagagagctcagatacagaggacagtgct
ggaggcgggccagagaccagggaagctctggctgagagcgaccgtgcagctgagggtctg
ggggctggagttgaggaggaaggagatgatgggaaggaaccccaagttgggggcagcccc
caacccctgagccatcccagcccagtgtggatgaactactcctacagcagcctgtgtttg
agcagcgaggagtcagaaagcagtggggaagatgaggagttctgggctgagctgcagagt
cttcggcagaagcacttgtcagaggtggaaacactacagacactacagaaaaaagaaatt
gaagatttgtacagccggctggggaagcagcccccaccgggtattgtggccccagctgct
atgctgtccagccgccagcgccgcctctccaagggcagcttccccacctcccgccgcaac
agcctacagcgctctgagcccccaggccctggcatcatgcgaaggaactctctgagtggc
agcagcaccggctcccaggagcagcgggcaagcaagggggtgacattcgccggggatgtt
ggcaggatgtga

All links

Ontology (1)   
   KEGG BRITE (1)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (8)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (4)   
   Pfam (4)   
All databases (51)   

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