KEGG   Homo sapiens (human): 6530Help
Entry
6530              CDS       T01001                                 

Gene name
SLC6A2, NAT1, NET, NET1, SLC6A5
Definition
(RefSeq) solute carrier family 6 member 2
  KO
K05035  
solute carrier family 6 (neurotransmitter transporter, noradrenalin) member 2
Organism
hsa  Homo sapiens (human)
Disease
H01031  
Orthostatic intolerance (OI)
Drug target
Amezinium metilsulfate: 
Amfetamine (DG00966): 
Amitifadine (DG01386): 
Amitriptyline (DG00934): 
Amitriptylinoxide: 
Amoxapine: 
Atomoxetine (DG00970): 
Centanafadine (DG01858): 
Clomipramine (DG00929): 
Cocaine (DG00808): 
Dasotraline: 
Desipramine (DG00927): 
Desvenlafaxine (DG00963): 
Dexamfetamine (DG00967): 
Dosulepin (DG00940): 
Doxepin (DG00937): 
Duloxetine (DG00962): 
Edivoxetine (DG01310): 
Esreboxetine (DG01309): 
Imipramine (DG00928): 
Imipraminoxide (DG01542): 
Levomilnacipran (DG01387): 
Liafensine: 
Lisdexamfetamine (DG00973): 
Lofepramine (DG00932): 
Maprotiline (DG00941): 
Mazindol: 
Metamfetamine (DG00968): 
Milnacipran (DG00960): 
Nisoxetine: 
Nomifensine: 
Nortriptyline (DG00935): 
Pyrovalerone hydrochloride: 
Reboxetine (DG00961): 
Sibutramine (DG00108): 
Talopram hydrochloride: 
Trimipramine (DG00931): 
Venlafaxine (DG00959): 
Viloxazine (DG00956): 
Brite
Transporters [BR:hsa02000]
 Solute Carrier Family (SLC)
  SLC6: Sodium- and chloride-dependent neurotransmitter transporter
   6530 (SLC6A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
16q12.2
AA seq 617 aa AA seqDB search
MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWG
KKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYN
REGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTW
NSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLC
LMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFY
RLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFA
IFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSS
MGGMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTS
ILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINF
KPLTYDDYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHL
VAQRDIRQFQLQHWLAI
NT seq 1854 nt NT seq  +upstreamnt  +downstreamnt
atgcttctggcgcggatgaacccgcaggtgcagcccgagaacaacggggcggacacgggt
ccagagcagccccttcgggcgcgcaaaactgcggagctgctggtggtgaaggagcgcaac
ggcgtccagtgcctgctggcgccccgcgacggcgacgcgcagccccgggagacctggggc
aagaagatcgacttcctgctgtccgtagtcggcttcgcagtggacctggccaacgtgtgg
cgcttcccctacctctgctacaagaacggcggcggtgccttcttgatcccgtacacactg
ttccttatcatcgcggggatgcccctgttctacatggagctggctctgggacagtacaac
cgggagggggctgccaccgtttggaaaatctgcccattcttcaaaggcgttggctatgct
gtcatcctgatcgccctgtacgttggcttctactacaacgtcatcatcgcctggtcactc
tactacctcttctcctccttcaccctcaacctgccctggaccgactgtggccacacctgg
aacagccccaactgtaccgaccccaagctcctcaatggctccgtgcttggcaaccacacc
aagtactccaagtacaagttcacgccggcagccgagttttatgagcgtggtgtcctgcac
cttcacgagagcagcgggattcatgacatcggcctgccccagtggcagctcttgctctgt
ctgatggtcgtcgtcatcgtcttgtattttagcctctggaaaggggtgaagacatcagga
aaggtggtgtggatcacagccacgctgccttacttcgtgctgttcgtgctcctggtccat
ggcgtcacgctgcccggagcctccaatggcatcaatgcctacctgcacatcgacttctac
cgcttgaaagaggccacggtatggattgatgccgcaactcagatatttttttccttgggg
gctggatttggagtattgattgcatttgccagttacaacaaatttgacaacaactgttac
agggatgccctgctgaccagcagcatcaactgtatcaccagcttcgtctctgggttcgcc
atcttctccatccttggttacatggcccatgaacacaaggtcaacattgaggatgtggcc
acagaaggagctggcctagtgttcatcctgtatccagaggccatttctaccctgtctgga
tctacattctgggctgttgtgtttttcgtcatgctcctggcgctgggccttgacagctca
atgggaggcatggaggctgtcatcacgggcctggcagatgacttccaggtcctgaagcga
caccggaaactcttcacatttggcgtcaccttcagcactttccttctcgccctgttctgc
ataaccaagggtggaatttacgtcttgaccctcctggacacctttgctgcgggcacctcc
atcctttttgctgtcctcatggaagccatcggagtttcctggttttatggagtggacagg
ttcagcaacgacatccagcagatgatggggttcaggccgggtctatactggagactgtgc
tggaagttcgtcagtcctgccttcctcctgttcgtggttgtggtcagcatcatcaacttc
aagccactcacctacgacgactacatcttcccgccctgggccaactgggtggggtggggc
atcgccctgtcctccatggtcctggtgcccatctacgtcatctataagttcctcagcacg
cagggctctctttgggagagactggcctatggcatcacgccagagaacgagcaccacctg
gtggctcagagggacatcagacagttccagttgcaacactggctggccatctga

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