KEGG   Homo sapiens (human): 6688Help
Entry
6688              CDS       T01001                                 

Gene name
SPI1, OF, PU.1, SFPI1, SPI-1, SPI-A
Definition
(RefSeq) Spi-1 proto-oncogene
  KO
K09438  
transcription factor PU.1
Organism
hsa  Homo sapiens (human)
Pathway
Osteoclast differentiation
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Transcriptional misregulation in cancer
Acute myeloid leukemia
Disease
H00003  
Acute myeloid leukemia (AML)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Development
   04380 Osteoclast differentiation
    6688 (SPI1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    6688 (SPI1)
   05202 Transcriptional misregulation in cancers
    6688 (SPI1)
   05221 Acute myeloid leukemia
    6688 (SPI1)
  Infectious diseases
   05166 HTLV-I infection
    6688 (SPI1)
   05169 Epstein-Barr virus infection
    6688 (SPI1)
Transcription factors [BR:hsa03000]
 Eukaryotic Type
  Helix-turn-helix
   Tryptophan clusters Ets-type
    6688 (SPI1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
Position
11p11.2
AA seq 270 aa AA seqDB search
MLQACKMEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHS
EFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQ
YPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLL
RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE
VKKVKKKLTYQFSGEVLGRGGLAERRHPPH
NT seq 813 nt NT seq  +upstreamnt  +downstreamnt
atgttacaggcgtgcaaaatggaagggtttcccctcgtcccccctccatcagaagacctg
gtgccctatgacacggatctataccaacgccaaacgcacgagtattacccctatctcagc
agtgatggggagagccatagcgaccattactgggacttccacccccaccacgtgcacagc
gagttcgagagcttcgccgagaacaacttcacggagctccagagcgtgcagcccccgcag
ctgcagcagctctaccgccacatggagctggagcagatgcacgtcctcgatacccccatg
gtgccaccccatcccagtcttggccaccaggtctcctacctgccccggatgtgcctccag
tacccatccctgtccccagcccagcccagctcagatgaggaggagggcgagcggcagagc
cccccactggaggtgtctgacggcgaggcggatggcctggagcccgggcctgggctcctg
cctggggagacaggcagcaagaagaagatccgcctgtaccagttcctgttggacctgctc
cgcagcggcgacatgaaggacagcatctggtgggtggacaaggacaagggcaccttccag
ttctcgtccaagcacaaggaggcgctggcgcaccgctggggcatccagaagggcaaccgc
aagaagatgacctaccagaagatggcgcgcgcgctgcgcaactacggcaagacgggcgag
gtcaagaaggtgaagaagaagctcacctaccagttcagcggcgaagtgctgggccgcggg
ggcctggccgagcggcgccacccgccccactga

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