KEGG T01001: 701

Homo sapiens (human): 701

Entry

701 CDS T01001

Gene name

BUB1B, BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1

Definition

BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1)

Orthology

K06637

mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa04110	Cell cycle
hsa05166	HTLV-I infection

Disease

H01288

Mosaic variegated aneuploidy (MVA) syndrome

Class

Cellular Processes; Cell growth and death; Cell cycle [PATH:hsa04110]
Human Diseases; Infectious diseases; HTLV-I infection [PATH:hsa05166]

SSDB

Motif

Pfam:

Mad3_BUB1_I Pkinase

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2WVI 3SI5 4GGD

Position

15q15

AA seq 1050 aa
MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKR
AFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPR
FLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQ
QKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARA
PIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPM
PRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEP
SINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVF
RKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKL
QIASESQKIPGMTLSSSVCQVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKK
NKSPPADPPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVT
ICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIY
SQTLSIKKLSPIIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQS
PWCSQYRRQLLKSLPELSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKL
FWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYIN
CFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDC
NKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLA
HLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMN
GVFDTTFQSHLNKALWKVGKLTSPGALLFQ

NT seq 3153 nt +upstreamnt +downstreamnt
atggcggcggtgaagaaggaagggggtgctctgagtgaagccatgtccctggagggagat
gaatgggaactgagtaaagaaaatgtacaacctttaaggcaagggcggatcatgtccacg
cttcagggagcactggcacaagaatctgcctgtaacaatactcttcagcagcagaaacgg
gcatttgaatatgaaattcgattttacactggaaatgaccctctggatgtttgggatagg
tatatcagctggacagagcagaactatcctcaaggtgggaaggagagtaatatgtcaacg
ttattagaaagagctgtagaagcactacaaggagaaaaacgatattatagtgatcctcga
tttctcaatctctggcttaaattagggcgtttatgcaatgagcctttggatatgtacagt
tacttgcacaaccaagggattggtgtttcacttgctcagttctatatctcatgggcagaa
gaatatgaagctagagaaaactttaggaaagcagatgcgatatttcaggaagggattcaa
cagaaggctgaaccactagaaagactacagtcccagcaccgacaattccaagctcgagtg
tctcggcaaactctgttggcacttgagaaagaagaagaggaggaagtttttgagtcttct
gtaccacaacgaagcacactagctgaactaaagagcaaagggaaaaagacagcaagagct
ccaatcatccgtgtaggaggtgctctcaaggctccaagccagaacagaggactccaaaat
ccatttcctcaacagatgcaaaataatagtagaattactgtttttgatgaaaatgctgat
gaggcttctacagcagagttgtctaagcctacagtccagccatggatagcaccccccatg
cccagggccaaagagaatgagctgcaagcaggcccttggaacacaggcaggtccttggaa
cacaggcctcgtggcaatacagcttcactgatagctgtacccgctgtgcttcccagtttc
actccatatgtggaagagactgcacaacagccagttatgacaccatgtaaaattgaacct
agtataaaccacatcctaagcaccagaaagcctggaaaggaagaaggagatcctctacaa
agggttcagagccatcagcaagcgtctgaggagaagaaagagaagatgatgtattgtaag
gagaagatttatgcaggagtaggggaattctcctttgaagaaattcgggctgaagttttc
cggaagaaattaaaagagcaaagggaagccgagctattgaccagtgcagagaagagagca
gaaatgcagaaacagattgaagagatggagaagaagctaaaagaaatccaaactactcag
caagaaagaacaggtgatcagcaagaagagacgatgcctacaaaggagacaactaaactg
caaattgcttccgagtctcagaaaataccaggaatgactctatccagttctgtttgtcaa
gtaaactgttgtgccagagaaacttcacttgcggagaacatttggcaggaacaacctcat
tctaaaggtcccagtgtacctttctccatttttgatgagtttcttctttcagaaaagaag
aataaaagtcctcctgcagatcccccacgagttttagctcaacgaagaccccttgcagtt
ctcaaaacctcagaaagcatcacctcaaatgaagatgtgtctccagatgtttgtgatgaa
tttacaggaattgaacccttgagcgaggatgccattatcacaggcttcagaaatgtaaca
atttgtcctaacccagaagacacttgtgactttgccagagcagctcgttttgtatccact
ccttttcatgagataatgtccttgaaggatctcccttctgatcctgagagactgttaccg
gaagaagatctagatgtaaagacctctgaggaccagcagacagcttgtggcactatctac
agtcagactctcagcatcaagaagctgagcccaattattgaagacagtcgtgaagccaca
cactcctctggcttctctggttcttctgcctcggttgcaagcacctcctccatcaaatgt
cttcaaattcctgagaaactagaacttactaatgagacttcagaaaaccctactcagtca
ccatggtgttcacagtatcgcagacagctactgaagtccctaccagagttaagtgcctct
gcagagttgtgtatagaagacagaccaatgcctaagttggaaattgagaaggaaattgaa
ttaggtaatgaggattactgcattaaacgagaatacctaatatgtgaagattacaagtta
ttctgggtggcgccaagaaactctgcagaattaacagtaataaaggtatcttctcaacct
gtcccatgggacttttatatcaacctcaagttaaaggaacgtttaaatgaagattttgat
catttttgcagctgttatcaatatcaagatggctgtattgtttggcaccaatatataaac
tgcttcacccttcaggatcttctccaacacagtgaatatattacccatgaaataacagtg
ttgattatttataaccttttgacaatagtggagatgctacacaaagcagaaatagtccat
ggtgacttgagtccaaggtgtctgattctcagaaacagaatccacgatccctatgattgt
aacaagaacaatcaagctttgaagatagtggacttttcctacagtgttgaccttagggtg
cagctggatgtttttaccctcagcggctttcggactgtacagatcctggaaggacaaaag
atcctggctaactgttcttctccctaccaggtagacctgtttggtatagcagatttagca
catttactattgttcaaggaacacctacaggtcttctgggatgggtccttctggaaactt
agccaaaatatttctgagctaaaagatggtgaattgtggaataaattctttgtgcggatt
ctgaatgccaatgatgaggccacagtgtctgttcttggggagcttgcagcagaaatgaat
ggggtttttgacactacattccaaagtcacctgaacaaagccttatggaaggtagggaag
ttaactagtcctggggctttgctctttcagtga

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (5)   
   KEGG DISEASE (1)   
   OMIM (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (13)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (29)   
   RefSeq(nuc) (1)   
   GenBank (14)   
   EMBL (14)   
3D Structure (3)   
   PDB (3)   
Protein domain (2)   
   Pfam (2)   
All databases (67)   

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