KEGG T01001: 7064

Homo sapiens (human): 7064

Entry

7064 CDS T01001

Gene name

THOP1, EP24.15, MEPD_HUMAN, MP78, TOP

Definition

thimet oligopeptidase 1 (EC:3.4.24.15)

Orthology

K01392

thimet oligopeptidase [EC:3.4.24.15]

Organism

hsa Homo sapiens (human)

Pathway

hsa04614	Renin-angiotensin system
hsa05143	African trypanosomiasis

Class

Organismal Systems; Endocrine system; Renin-angiotensin system [PATH:hsa04614]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:hsa05143]

SSDB

Motif

Pfam:

Peptidase_M3

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

Structure

PDB:

2O36 1S4B

Position

19p13.3

AA seq 689 aa
MKPPAACAGDMADAASPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVS
YESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQ
RIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNK
NLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKV
EEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQ
KLKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYF
PVQVVTHGLLGIYQELLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREG
KYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMH
QLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLI
ESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGH
LAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRR
FLGRDPKQDAFLLSKGLQVGGCEPEPQVC

NT seq 2070 nt +upstreamnt +downstreamnt
atgaagccccccgcagcctgtgcaggagacatggcggacgcagcatctccgtgctctgtg
gtaaacgacctgcggtgggacctgagtgcccagcagatagaggagcgcaccagggagctc
atcgagcagaccaagcgcgtgtatgaccaggttggcacccaggagtttgaggacgtgtcc
tacgagagcacgctcaaggcgctggccgatgtggaggtcacctacacagttcagaggaat
atccttgacttcccccagcatgtttccccctccaaggacatccggacagccagcacagag
gccgacaagaagctctctgagttcgacgtggagatgagcatgagggaggacgtgtaccag
aggatcgtgtggctccaggagaaagttcagaaggactcactgaggcccgaggctgcgcgg
tacctggagcggctaatcaagctgggccggagaaatgggcttcacctccccagagagact
caggaaaacatcaaacgcatcaagaagaagctgagccttctgtgcatcgacttcaacaag
aacctgaacgaggacacgaccttcctgcccttcacgctccaggagctaggagggctcccc
gaggactttctgaactccctggagaagatggaggacggcaagttgaaggtcaccctcaag
tacccccattacttccccctcctgaagaaatgccacgtgcctgagaccaggaggaaagtg
gaggaggccttcaactgccggtgcaaggaggagaactgcgctatcctcaaggagctggtg
acgctgcgggcccagaagtcccgcctgctggggttccacacgcacgccgactatgtcctg
gagatgaacatggccaagaccagccagaccgtggccaccttcctagatgagctggcgcag
aagctgaagcccctgggggagcaggagcgtgcggtgattctggagctgaagcgtgcggag
tgcgagcgccggggcctgcccttcgacggccgcatccgtgcctgggacatgcgctactac
atgaaccaggtggaggagacgcgctactgcgtggaccagaacctgctcaaggagtacttc
cccgtgcaggtggtcacgcacgggctgctgggcatctaccaggagctcctggggctggcc
ttccaccacgaggagggcgccagtgcctggcatgaggacgtgcggctctacaccgcgagg
gacgcggcctcgggggaggtggtcggcaagttctacctggacctgtacccgcgggaagga
aagtacgggcacgcggcctgctttggcctgcagcccggctgcctgcggcaggatgggagc
cgccagatcgccatcgcggccatggtggccaacttcaccaagcccacagccgacgcgccc
tcgctgctgcagcatgacgaggtggagacctacttccatgagtttggccacgtgatgcac
cagctctgctcccaggcggagttcgccatgttcagcgggacccacgtggagcgggacttt
gtggaggcgccgtcgcagatgctggagaactgggtgtgggagcaggagccgctgctgcgg
atgtcgcggcactaccgcacaggcagcgccgtgccccgggagctcctggagaagctcatt
gagtcccggcaggccaacacaggcctcttcaacctgcgccagatcgtcctcgccaaggtg
gaccaggccctgcacacgcagacggacgcagaccccgccgaggagtatgcgcggctctgc
caggagatcctcggggtcccggccacgccaggaaccaacatgcctgcaaccttcggccat
ctggcaggtggctacgacgcccagtactacgggtacctgtggagcgaggtgtattccatg
gacatgttccacacgcgcttcaagcaggagggtgtcctgaacagcaaggttggcatggat
tacagaagctgcatcctgagacccggcggttccgaggatgccagcgccatgctgaggcgc
ttcctgggccgtgaccccaagcaggacgccttcctcctgagcaaggggctgcaggtcggg
ggctgcgagcccgagccgcaggtctgctga

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (10)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   Pfam (1)   
All databases (49)   

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